Search filters

List of works by Motoaki Ohtsubo

A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons ⬇️

scientific article published on September 1, 1998

A new protein containing an SH2 domain that inhibits JAK kinases

scientific article

A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients.

scientific article published in July 2007

CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo.

scientific article published on 11 April 2013

Cloning and Characterization of a Novel Class II Phosphoinositide 3-Kinase Containing C2 Domain ⬇️

scientific article published on March 17, 1998

Cloning and characterization of novel CIS family genes

scientific article

Complete nucleotide sequence of the human RCC1 gene involved in coupling between DNA replication and mitosis ⬇️

scientific article published on October 1, 1991

Cyclin E overexpression responsible for growth of human hepatic tumors with p21WAF1/CIP1/SDI1

scientific article published on 01 January 1998

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

scientific article published on March 1993

Decreased expression in nuclear factor-κB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immunodeficiency.

scientific article

Hoxa9 Transduction Induces Hematopoietic Stem and Progenitor Cell Activity through Direct Down-Regulation of Geminin Protein ⬇️

scientific article published on January 11, 2013

Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.

scientific article published on April 2004

Inhibition of proteasome-dependent degradation of Wee1 in G2-arrested Hep3B cells by TGF beta 1.

scientific article published on April 2003

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis ⬇️

scientific article published on June 1, 1991

Loss of p53 induces M-phase retardation following G2 DNA damage checkpoint abrogation.

scientific article published in April 2003

MDM2 interacts with MDMX through their RING finger domains

scientific article (publication date: 19 March 1999)

Manipulation of Cell Cycle and Chromatin Configuration by Means of Cell-Penetrating Geminin

scientific article

Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency.

scientific article published on 08 April 2010

Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase

scientific article published on 9 February 2018

Neurodevelopmental abnormalities associated with severe congenital neutropenia due to the R86X mutation in the HAX1 gene.

scientific article published on 8 July 2008

Nuclear export signal in CDC25B.

scientific article published in March 2004

Overexpression of BMI-1 correlates with drug resistance in B-cell lymphoma cells through the stabilization of survivin expression.

scientific article

Passive carriage of rabies virus by dendritic cells

scientific article published on 29 August 2013

Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity.

scholarly article

Role of Geminin in cell fate determination of hematopoietic stem cells (HSCs).

scientific article published on 15 July 2016

Role of cyclin E and cyclin E‐dependent kinase in mitogenic stimulation by cementum‐derived growth factor in human fibroblasts ⬇️

scientific article published on September 1, 1998

Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53

scientific article published on 01 October 1999

STAT5 activation correlates with erythropoietin receptor-mediated erythroid differentiation of an erythroleukemia cell line.

scientific article published on March 1997

Significance of ACADM mutations identified through newborn screening of MCAD deficiency in Japan

scientific article published on 29 December 2015

The yeast SRM1 protein and human RCC1 protein share analogous functions ⬇️

scientific article published on October 1, 1991

Transcription of the Geminin gene is regulated by a negative-feedback loop.

scientific article published on 19 February 2014

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells ⬇️

scientific article published on May 1, 2003

Paulina is supported by:

About Paulina

Help