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List of works by Ole Petter Rekvig

A central role of nucleosomes in lupus nephritis

scientific article published on June 2007

A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS).

scientific article published on 24 November 2016

A longitudinal study of human cytomegalovirus serology and viruria fails to detect active viral infection in 20 systemic lupus erythematosus patients

scientific article published in January 2000

Acquired Loss of Renal Nuclease Activity Is Restricted to DNaseI and Is an Organ-Selective Feature in Murine Lupus Nephritis

scientific article published on June 30, 2011

Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis

scientific article published on January 2006

Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development

scientific article published on February 1, 2011

Anti-DNA antibodies induced by BK virus inoculations. Demonstration of the specificities for eukaryotic dsDNA and synthetic polynucleotides

scientific article published in August 1990

Anti-DNA antibody subpopulations and lupus nephritis

scientific article published on February 2004

Anti-double-stranded DNA antibodies, nucleosomes, and systemic lupus erythematosus: a time for new paradigms?

scientific article

Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: critical remarks

scientific article

Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice

scientific article

Antibodies to dsDNA are produced during primary BK virus infection in man, indicating that anti-dsDNA antibodies may be related to virus replication in vivo

scientific article published in October 1993

Antibodies to eukaryotic, including autologous, native DNA are produced during BK virus infection, but not after immunization with non-infectious BK DNA.

scientific article published in September 1992

Antibodies to viral and mammalian native DNA in response to BK virus inoculation and subsequent immunization with calf thymus DNA.

scientific article published in July 1991

Autoantibodies in lupus: culprits or passive bystanders?

scientific article published on 25 October 2011

BK and JC viruses in patients with systemic lupus erythematosus: prevalent and persistent BK viruria, sequence stability of the viral regulatory regions, and nondetectable viremia

scientific article published in July 1999

BK virus terminates tolerance to dsDNA and histone antigens in vivo

scientific article published in April 1990

Chromatin as a target antigen in human and murine lupus nephritis

scientific article published on April 18, 2011

Circulating levels of chromatin fragments are inversely correlated with anti-dsDNA antibody levels in human and murine systemic lupus erythematosus

scientific article published on April 17, 2011

Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study

scientific article published on April 2014

Cross-reacting rheumatoid factors and lupus erythematosus (LE)-factors

scientific article published on 01 January 1981

Development of lupus nephritis is associated with qualitative changes in the glomerular collagen IV matrix composition

scientific article published in April 2009

Differences in the reactivity of CD4+ T-cell lines generated against free versus nucleosome-bound SV40 large T antigen

scientific article published on April 2001

European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies

scientific article published on 5 November 2009

Experimental expression in mice and spontaneous expression in human SLE of polyomavirus T-antigen. A molecular basis for induction of antibodies to DNA and eukaryotic transcription factors

scientific article published on April 1997

Future Perspectives on Pathogenesis of Lupus Nephritis: Facts, Problems, and Potential Causal Therapy Modalities

scientific article published on 21 September 2016

Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis

scientific article published on December 2008

Glomerular targets for autoantibodies in lupus nephritis--an apoptotic origin

scientific article published on June 2007

Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus

scientific article published on July 2008

Heparin exerts a dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes

scientific article published on April 1, 2011

Human polyomavirus BK and immunogenicity of mammalian DNA: a conceptual framework

scientific article published on 01 January 1997

IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene

scientific article published on 6 February 2018

Identification of antihistone antibodies in subsets of juvenile chronic arthritis.

scientific article

Immunity and autoimmunity to dsDNA and chromatin--the role of immunogenic DNA-binding proteins and nuclease deficiencies

scientific article published on 26 September 2012

Impact of the tumor necrosis factor receptor-associated protein 1 (Trap1) on renal DNaseI shutdown and on progression of murine and human lupus nephritis

scientific article

In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

scientific article

Inoculation with BK virus may break immunological tolerance to histone and DNA antigens

scientific article

Interleukin-2, but not interleukin-15, is required to terminate experimentally induced clonal T-cell anergy

scientific article published in July 2004

Is closer linkage between systemic lupus erythematosus and anti-double-stranded DNA antibodies a desirable and attainable goal?

scientific article

Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up Scandinavian multicentre study

scientific article published on March 16, 2013

Lupus Erythematosus (LE) Factors Recognize both Nucleosomes and Viable Human Leucocytes

scientific article published on 01 January 1981

Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept

scientific article published on July 24, 2013

Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease

scientific article

Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression.

scientific article

Lupus nephritis: the central role of nucleosomes revealed

scientific article

Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens

scientific article published on January 1997

Meningococcal septicaemia treated with combined plasmapheresis and leucapheresis or with blood exchange.

scientific article

Molecular analyses of anti-DNA antibodies induced by polyomavirus BK in BALB/c mice

scientific article

Molecular analyses of anti-DNA antibodies induced by polyomavirus BK in BALB/c mice

scientific article published on 01 August 1995

Murine and Human Lupus Nephritis: Pathogenic Mechanisms and Theoretical Strategies for Therapy

scientific article published on September 2015

Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells

scientific article published on June 2006

Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes

scientific article published on April 2009

Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB × NZW) F1 mice

scientific article published on 15 June 2010

Nucleosomes possess a high affinity for glomerular laminin and collagen IV and bind nephritogenic antibodies in murine lupus-like nephritis

scientific article published on 15 May 2007

On the biological origin of anti-double-stranded (ds) DNA antibodies: systemic lupus erythematosus-related anti-dsDNA antibodies are induced by polyomavirus BK in lupus-prone (NZBxNZW) F1 hybrids, but not in normal mice

Progression of murine lupus nephritis is linked to acquired renal Dnase1 deficiency and not to up-regulated apoptosis

scientific article published on 15 June 2009

Reduced fragmentation of apoptotic chromatin is associated with nephritis in lupus-prone (NZB x NZW)F(1) mice

scientific article published in March 2008

Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis

scientific article published on August 10, 2010

Review: antinucleosome antibodies: a critical reflection on their specificities and diagnostic impact

scientific article

Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e

scientific article

Simian virus 40 large T-antigen, but not small T-antigen, trans-activates the human cytomegalovirus major immediate early promoter

scientific article published on January 1, 2001

Stimulation of clones specific for dsDNA or idiotypes of anti-dsDNA as a consequence of BK virus inoculation

scientific article published in June 1989

Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas

scientific article published in March 2018

T cell lines specific for polyomavirus T-antigen recognize T-antigen complexed with nucleosomes: a molecular basis for anti-DNA antibody production

scientific article published on September 1999

TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form

scientific article published on 11 June 2015

The dsDNA, Anti-dsDNA Antibody, and Lupus Nephritis: What We Agree on, What Must Be Done, and What the Best Strategy Forward Could Be.

scientific article published on 15 May 2019

The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved

scientific article published on 25 April 2014