List of works - Ming-Feng Hou

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Association analysis identifies 65 new breast cancer risk loci

scientific article published on 23 October 2017

Serum adiponectin and leptin levels in Taiwanese breast cancer patients.

scientific article published on 12 July 2005

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium

scientific article

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis

scientific article

Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties

scientific article published on 3 June 2013

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway.

scientific article

MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle

scientific article published on 10 May 2012

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

scientific article published on 27 March 2013

Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK.

scientific article published on 16 January 2013

Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells.

scientific article

Long noncoding RNAs-related diseases, cancers, and drugs

scientific article

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis.

scientific article published on 22 September 2017

Distant metastasis in triple-negative breast cancer

scientific article published on January 1, 2013

Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

scientific article

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

scientific article

Resistin expression in breast cancer tissue as a marker of prognosis and hormone therapy stratification.

scientific article published on 24 February 2012

Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells.

scientific article published on 6 September 2011

STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression.

scientific article published on 10 November 2014

Combination of multiple mRNA markers (PTTG1, Survivin, UbcH10 and TK1) in the diagnosis of Taiwanese patients with breast cancer by membrane array.

scientific article published in January 2006

High visfatin expression in breast cancer tissue is associated with poor survival.

scientific article

Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells.

scientific article published on 13 September 2011

MMP13 is potentially a new tumor marker for breast cancer diagnosis.

scientific article

Association of vitamin D receptor gene polymorphism with sporadic breast cancer in Taiwanese patients.

scientific article published in July 2002

Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy.

scientific article

11q13 is a susceptibility locus for hormone receptor positive breast cancer

scientific article

Molecular characterization of germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in Taiwan

scientific article published on 01 March 1999

A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis

scientific article published on September 5, 2013

Orai1/CRACM1 overexpression suppresses cell proliferation via attenuation of the store-operated calcium influx-mediated signalling pathway in A549 lung cancer cells

scientific article published on July 14, 2011

Role of MRE11 in Cell Proliferation, Tumor Invasion, and DNA Repair in Breast Cancer

scientific article published on August 22, 2012

The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse.

scientific article

Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer

scientific article published on March 1, 2010

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis

scientific article

miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis.

scientific article

Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway.

scientific article published on February 2011

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

scientific article

Evaluating the performance of fibronectin 1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC).

scientific article published on 2 November 2012

The synthetic β-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway

scientific article published on 9 December 2015

Expression of CXCR4 is associated with axillary lymph node status in patients with early breast cancer

scientific article published on 18 October 2005

Cyclooxygenase-2 up-regulates CCR7 expression via AKT-mediated phosphorylation and activation of Sp1 in breast cancer cells.

scientific article published in February 2013

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

scientific article published on 03 September 2016

DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers.

scientific article

Comparison of local recurrence and distant metastases between breast cancer patients after postmastectomy radiotherapy with and without immediate TRAM flap reconstruction.

scientific article published in October 2006

List of works by Ming-Feng Hou

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

Association analysis identifies 65 new breast cancer risk loci

Serum adiponectin and leptin levels in Taiwanese breast cancer patients.

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis

Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway.

MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK.

Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells.

Long noncoding RNAs-related diseases, cancers, and drugs

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis.

Distant metastasis in triple-negative breast cancer

Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

Resistin expression in breast cancer tissue as a marker of prognosis and hormone therapy stratification.

Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells.

STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression.

Combination of multiple mRNA markers (PTTG1, Survivin, UbcH10 and TK1) in the diagnosis of Taiwanese patients with breast cancer by membrane array.

High visfatin expression in breast cancer tissue is associated with poor survival.

Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells.

MMP13 is potentially a new tumor marker for breast cancer diagnosis.

Association of vitamin D receptor gene polymorphism with sporadic breast cancer in Taiwanese patients.

Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy.

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Molecular characterization of germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in Taiwan

A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis

Orai1/CRACM1 overexpression suppresses cell proliferation via attenuation of the store-operated calcium influx-mediated signalling pathway in A549 lung cancer cells

Role of MRE11 in Cell Proliferation, Tumor Invasion, and DNA Repair in Breast Cancer

The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse.

Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis

miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis.

Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway.

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

Evaluating the performance of fibronectin 1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC).

The synthetic β-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway

Expression of CXCR4 is associated with axillary lymph node status in patients with early breast cancer

Cyclooxygenase-2 up-regulates CCR7 expression via AKT-mediated phosphorylation and activation of Sp1 in breast cancer cells.

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers.

Comparison of local recurrence and distant metastases between breast cancer patients after postmastectomy radiotherapy with and without immediate TRAM flap reconstruction.