List of works - William R. Roush - Paulina

List of works by William R. Roush

4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection

scientific article published on 27 December 2017

An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation

scientific article published on 23 March 2021

Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer

scientific article published on 15 December 2017

Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

scientific article published on 11 November 2020

Enantio- and Diastereoselective Synthesis of 1,5-syn-(Z)-Amino Alcohols via Imine Double Allylboration: Synthesis of trans-1,2,3,6-Tetrahydropyridines and Total Synthesis of Andrachcine.

scientific article published on 04 May 2017

Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma-Induced Osteolysis and Reduces Overall Survival

scientific article published on 01 February 2021

In Silico HTS and Structure Based Optimization of Indazole-Derived ULK1 Inhibitors.

scientific article published on 22 November 2017

Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases.

scientific article published on 10 April 2017

Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation

scientific article published on 17 April 2017

Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors.

scientific article published on 27 June 2017

Targeting casein kinase 1 delta sensitizes pancreatic and bladder cancer cells to gemcitabine treatment by upregulating deoxycytidine kinase

scientific article published on 19 May 2020

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