List of works - Luiz Zerbini

A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.

scientific article published on December 2006

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation

scientific article published on 02 September 2005

Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke.

scientific article published on 17 June 2014

Adenosine uptake is the major effector of extracellular ATP toxicity in human cervical cancer cells.

scientific article

Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle

scientific article published on 05 September 2007

Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.

scientific article

COL1A2 is a TBX3 target that mediates its impact on fibrosarcoma and chondrosarcoma cell migration

scientific article published on 13 June 2019

Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer

scientific article

Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer

scientific article published on 26 January 2021

Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy

scientific article

Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.

scientific article published in October 2002

Computational repositioning and preclinical validation of pentamidine for renal cell cancer.

scientific article

Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.

scientific article published in May 2003

Correction: Genomic Counter-Stress Changes Induced by the Relaxation Response

scientific article published on 21 February 2017

Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.

scientific article published on 29 July 2015

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

scientific article

Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites

scientific article published in February 2010

Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl

scientific article published on 19 February 2019

Discovery of novel candidate urinary protein biomarkers for prostate cancer in a multiethnic cohort of South African patients via label-free mass spectrometry.

scientific article published on 3 May 2015

Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer

scientific article published on 29 April 2013

E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings

scientific article

Ectonucleotidase expression profile and activity in human cervical cancer cell lines.

scientific article published on 8 January 2014

Emerging proteomics biomarkers and prostate cancer burden in Africa.

scientific article

Exisulind induces apoptosis in advanced myelodysplastic syndrome (MDS) and acute myeloid leukaemia/MDS

scientific article published on 15 September 2006

Expression and purification of a recombinant adenovirus fiber knob in a baculovirus system.

scientific article

GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets

scientific article published on September 2005

GADD45 proteins: central players in tumorigenesis

scientific article

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes

scientific article

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

scientific article published on 12 February 2016

GC-MS based comparative metabolomic analysis of MCF-7 and MDA-MB-231 cancer cells treated with Tamoxifen and/or Paclitaxel

scientific article published on 10 June 2020

Genes coding for Shiga-like toxins in bovine verotoxin-producing Escherichia coli (VTEC) strains belonging to different O:K:H serotypes

article

Genomic counter-stress changes induced by the relaxation response

scientific article

Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells

scientific article

In silico verification and parallel reaction monitoring prevalidation of potential prostate cancer biomarkers.

scientific article

Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma.

scientific article

Insertion of an exogenous domain in the adenovirus type 2 fiber globular region.

scientific article published on August 2002

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

scientific article

Life and death in cancer. GADD45 alpha and gamma are critical regulators of NF-kappaB mediated escape from programmed cell death

scientific article published on 11 January 2005

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

scientific article

NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo.

scientific article published on 11 May 2012

NTPDase and 5' ecto-nucleotidase expression profiles and the pattern of extracellular ATP metabolism in the Walker 256 tumor.

scientific article

Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

scientific article published on 12 February 2016

Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes

scientific journal article

P2Y2 receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway

scientific article published on 29 October 2020

Potential role of P2X7R in esophageal squamous cell carcinoma proliferation

scientific article

Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations.

scientific article published on July 2004

Proteomic analysis of a PDEF Ets transcription factor-interacting protein complex

scientific article

Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.

scientific article published on May 2007

Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.

scientific article

SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1

scientific article

Structural Transformation to Attain Responsible BIOSciences (STARBIOS2): Protocol for a Horizon 2020 Funded European Multicenter Project to Promote Responsible Research and Innovation

article

Structural analysis of human respiratory syncytial virus p protein: identification of intrinsically disordered domains.

scientific article published on January 2011

Targeting neddylation in cancer therapy

scientific article

Targeting transcription factors for cancer gene therapy.

scientific article

The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An Overview

scientific article published on 12 October 2018

The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes

scientific article published on 01 April 2005

The Prospect and Challenges to the Flow of Liquid Biopsy in Africa

scientific article published on 09 August 2019

The crossroads of breast cancer progression: insights into the modulation of major signaling pathways

scientific article published on 20 November 2017

The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence

scientific article published on 22 January 2009

The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.

scientific article

The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome

scientific article published on 8 June 2005

The novel compound OSI-461 induces apoptosis and growth arrest in human acute myeloid leukemia cells ⬇️

scientific article published on June 30, 2011

The oncogenic TBX3 is a downstream target and mediator of the TGF-β1 signaling pathway

scientific article published on 11 September 2013

The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.

scientific article published on 04 June 2013

The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target.

scientific article

List of works by Luiz Zerbini

A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation

Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke.

Adenosine uptake is the major effector of extracellular ATP toxicity in human cervical cancer cells.

Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle

Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.

COL1A2 is a TBX3 target that mediates its impact on fibrosarcoma and chondrosarcoma cell migration

Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer

Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer

Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy

Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.

Computational repositioning and preclinical validation of pentamidine for renal cell cancer.

Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.

Correction: Genomic Counter-Stress Changes Induced by the Relaxation Response

Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites

Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl

Discovery of novel candidate urinary protein biomarkers for prostate cancer in a multiethnic cohort of South African patients via label-free mass spectrometry.

Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer

E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings

Ectonucleotidase expression profile and activity in human cervical cancer cell lines.

Emerging proteomics biomarkers and prostate cancer burden in Africa.

Exisulind induces apoptosis in advanced myelodysplastic syndrome (MDS) and acute myeloid leukaemia/MDS

Expression and purification of a recombinant adenovirus fiber knob in a baculovirus system.

GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets

GADD45 proteins: central players in tumorigenesis

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

GC-MS based comparative metabolomic analysis of MCF-7 and MDA-MB-231 cancer cells treated with Tamoxifen and/or Paclitaxel

Genes coding for Shiga-like toxins in bovine verotoxin-producing Escherichia coli (VTEC) strains belonging to different O:K:H serotypes

Genomic counter-stress changes induced by the relaxation response

Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells

In silico verification and parallel reaction monitoring prevalidation of potential prostate cancer biomarkers.

Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma.

Insertion of an exogenous domain in the adenovirus type 2 fiber globular region.

Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene

Life and death in cancer. GADD45 alpha and gamma are critical regulators of NF-kappaB mediated escape from programmed cell death

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo.

NTPDase and 5' ecto-nucleotidase expression profiles and the pattern of extracellular ATP metabolism in the Walker 256 tumor.

Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes

P2Y2 receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway

Potential role of P2X7R in esophageal squamous cell carcinoma proliferation

Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations.

Proteomic analysis of a PDEF Ets transcription factor-interacting protein complex

Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.

Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.

SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1

Structural Transformation to Attain Responsible BIOSciences (STARBIOS2): Protocol for a Horizon 2020 Funded European Multicenter Project to Promote Responsible Research and Innovation

Structural analysis of human respiratory syncytial virus p protein: identification of intrinsically disordered domains.

Targeting neddylation in cancer therapy

Targeting transcription factors for cancer gene therapy.

The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An Overview

The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes

The Prospect and Challenges to the Flow of Liquid Biopsy in Africa

The crossroads of breast cancer progression: insights into the modulation of major signaling pathways

The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence

The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.

The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome

The novel compound OSI-461 induces apoptosis and growth arrest in human acute myeloid leukemia cells ⬇️

The oncogenic TBX3 is a downstream target and mediator of the TGF-β1 signaling pathway

The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.

The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target.