List of works - Luciana Giardino

A single prenatal exposure to the endocrine disruptor 2,3,7,8-tetrachlorodibenzo-p-dioxin alters developmental myelination and remyelination potential in the rat brain.

scientific article published on 28 September 2010

Age-Related Changes of the Neurovascular Unit in the Cerebral Cortex of Alzheimer Disease Mouse Models: A Neuroanatomical and Molecular Study

scientific article published on 01 February 2019

Age-dependent impairment of hippocampal neurogenesis in chronic cerebral hypoperfusion

scientific journal article

Autoradiographic Detection of Substance P Receptors in Normal and Psoriatic Skin ⬇️

scientific article published on 01 September 1993

CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice.

scientific article

CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice

scientific article

CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study.

scientific article published on September 2013

CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice.

scientific article published on 28 January 2013

Cellular approaches to central nervous system remyelination stimulation: thyroid hormone to promote myelin repair via endogenous stem and precursor cells.

scientific article published on 03 July 2009

Cytokine and chemokine alterations in tissue, CSF, and plasma in early presymptomatic phase of experimental allergic encephalomyelitis (EAE), in a rat model of multiple sclerosis

scientific article

Deficit of galanin-like immunostaining in the median eminence of adult hypothyroid rats

scientific article published on March 1, 1992

Dopamine receptors in the striatum of rats exposed to repeated restraint stress and alprazolam treatment.

scientific article

Effect of chronic clozapine administration on [3H]MK801-binding sites in the rat brain: a side-preference action in cortical areas.

scientific article published in July 1997

Effect of radiofrequency electromagnetic field exposure on in vitro models of neurodegenerative disease.

scientific article

Effect of sertraline treatment on benzodiazepine receptors in the rat brain

scientific article published on 01 January 1993

Endogenous stem and precursor cells for demyelinating diseases: an alternative for transplantation?

scientific article published on July 2006

Expression analysis and protein localization of the human HPC-1/syntaxin 1A, a gene deleted in Williams syndrome.

scientific article published in December 1999

From the multifactorial nature of Alzheimer`s disease to multitarget therapy: the contribution of the translational approach.

scientific article published on January 2013

Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis.

scientific article published in August 2012

Further evidence for a role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine treatment modifies its clinical evolution

scientific article published on 01 February 2000

Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.

scientific article published on 9 September 2009

Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis

scientific article

Growth and Neurotrophic Factors in Embryonic Stem Cells

scientific article published in January 2018

Hormonal influences on brain ageing quality: focus on corticotropin releasing hormone-, vasopressin- and oxytocin-immunoreactive neurones in the human brain

scientific article published on 01 January 1997

Human mesenchymal stem cells produce bioactive neurotrophic factors: source, individual variability and differentiation issues

scientific article published in July 2014

In Vitro Testing of Biomaterials for Neural Repair: Focus on Cellular Systems and High-Content Analysis

scientific article

In vitro exposure to very low-level laser modifies expression level of extracellular matrix protein RNAs and mitochondria dynamics in mouse embryonic fibroblasts.

scientific article published on 24 March 2015

In vivo regulation of precursor cells in the subventricular zone of adult rat brain by thyroid hormone and retinoids

scientific article published on 01 December 2000

Inflammation severely alters thyroid hormone signaling in the central nervous system during experimental allergic encephalomyelitis in rat: Direct impact on OPCs differentiation failure.

scientific article published on 12 July 2016

Inhibin and activin in human fetal membranes: evidence for a local effect on prostaglandin release.

scientific article published on August 1993

Intravitreal NGF administration counteracts retina degeneration after permanent carotid artery occlusion in rat.

scientific article

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

scientific article

Multiple neurochemical action of clozapine: A quantitative autoradiographic study of DA 2, opiate and benzodiazepine receptors in the rat brain after long-term treatment ⬇️

scientific article published on 01 January 1991

Muscarinic and gamma-aminobutyric acid-ergic receptor changes during vestibular compensation. A quantitative autoradiographic study of the vestibular nuclei complex in the rat

scientific article published on January 1, 1992

NGF content and expression in the rat pituitary gland and regulation by thyroid hormone ⬇️

scientific article published on November 1, 1997

Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors.

scholarly article

Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.

scientific article

Neuroprotection and aging of the cholinergic system: a role for the ergoline derivative nicergoline (Sermion).

scientific article

Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture.

scientific article

Opiate receptor modifications in the rat brain after chronic treatment with haloperidol and suipiride.

scientific article published in January 1990

PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation

scientific article

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects.

scientific article published in July 2013

Plasticity of GABA(a) system during ageing: focus on vestibular compensation and possible pharmacological intervention.

scientific article published in March 2002

Prenatal glucocorticoid exposure affects learning and vulnerability of cholinergic neurons.

scientific article published on 6 January 2006

Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: In vivo evidence of a role for nerve growth factor ⬇️

scientific article published on March 17, 1998

Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer's and other neurodegenerative diseases

scientific article

Regulation of VIP mRNA expression by thyroid hormone in different brain areas of adult rat

scientific article published on 01 November 1994

Response of hypothalamic peptide mRNAs to thyroidectomy

scientific article published on November 1, 1992

Role of the Thyroid System in Myelination and Neural Connectivity.

scientific article published on July 2015

Sexual impotence is associated with a reduced production of oxytocin and with an increased production of opioid peptides in the paraventricular nucleus of male rats.

scientific article published in September 1997

Spinal motoneurone distress during experimental allergic encephalomyelitis.

scientific article

Stress promotes major changes in dopamine receptor densities within the mesoaccumbens and nigrostriatal systems.

scientific article published in May 1998

The effect of oxytocin on feeding, drinking, and male copulatory behavior is not diminished by neonatal monosodium glutamate

scientific article published on 01 December 1993

The role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cells

scientific article published on 17 April 2019

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

scientific article published in January 2011

Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair

scientific article

Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis

scientific article

Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease

scientific journal article

Thyroid hormone and remyelination in adult central nervous system: a lesson from an inflammatory-demyelinating disease

scientific article published on 26 January 2005

Thyroid hormone and retinoids affect motoneuron phenotype and reaction after axotomy in the spinal cord of adult rats.

scientific article published in January 2002

Thyroid hormone participates in the regulation of neural stem cells and oligodendrocyte precursor cells in the central nervous system of adult rat.

scientific article published in October 2004

Thyroid hormone regulates NGF content and p75LNGFR expression in the basal forebrain of adult rats

scientific article published on 01 February 1997

Thyroid hormone-induced plasticity in the adult rat brain.

scientific article published on January 1997

Time-course changes of nerve growth factor, corticotropin-releasing hormone, and nitric oxide synthase isoforms and their possible role in the development of inflammatory response in experimental allergic encephalomyelitis.

scientific article

Triiodothyronine administration ameliorates the demyelination/remyelination ratio in a non-human primate model of multiple sclerosis by correcting tissue hypothyroidism.

scientific article

Ultra-low-level laser therapy.

scientific article

Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.

scientific article published on 24 February 2017

[1-13C]Glucose entry in neuronal and astrocytic intermediary metabolism of aged rats. A study of the effects of nicergoline treatment by 13C NMR spectroscopy.

scientific article published in March 2003

p75(NTR)-immunoreactivity in the subventricular zone of adult male rats: expression by cycling cells.

scientific article published in November 2004

List of works by Luciana Giardino

A single prenatal exposure to the endocrine disruptor 2,3,7,8-tetrachlorodibenzo-p-dioxin alters developmental myelination and remyelination potential in the rat brain.

Age-Related Changes of the Neurovascular Unit in the Cerebral Cortex of Alzheimer Disease Mouse Models: A Neuroanatomical and Molecular Study

Age-dependent impairment of hippocampal neurogenesis in chronic cerebral hypoperfusion

Autoradiographic Detection of Substance P Receptors in Normal and Psoriatic Skin ⬇️

CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice.

CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice

CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study.

CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice.

Cellular approaches to central nervous system remyelination stimulation: thyroid hormone to promote myelin repair via endogenous stem and precursor cells.

Cytokine and chemokine alterations in tissue, CSF, and plasma in early presymptomatic phase of experimental allergic encephalomyelitis (EAE), in a rat model of multiple sclerosis

Deficit of galanin-like immunostaining in the median eminence of adult hypothyroid rats

Dopamine receptors in the striatum of rats exposed to repeated restraint stress and alprazolam treatment.

Effect of chronic clozapine administration on [3H]MK801-binding sites in the rat brain: a side-preference action in cortical areas.

Effect of radiofrequency electromagnetic field exposure on in vitro models of neurodegenerative disease.

Effect of sertraline treatment on benzodiazepine receptors in the rat brain

Endogenous stem and precursor cells for demyelinating diseases: an alternative for transplantation?

Expression analysis and protein localization of the human HPC-1/syntaxin 1A, a gene deleted in Williams syndrome.

From the multifactorial nature of Alzheimer`s disease to multitarget therapy: the contribution of the translational approach.

Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis.

Further evidence for a role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine treatment modifies its clinical evolution

Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.

Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis

Growth and Neurotrophic Factors in Embryonic Stem Cells

Hormonal influences on brain ageing quality: focus on corticotropin releasing hormone-, vasopressin- and oxytocin-immunoreactive neurones in the human brain

Human mesenchymal stem cells produce bioactive neurotrophic factors: source, individual variability and differentiation issues

In Vitro Testing of Biomaterials for Neural Repair: Focus on Cellular Systems and High-Content Analysis

In vitro exposure to very low-level laser modifies expression level of extracellular matrix protein RNAs and mitochondria dynamics in mouse embryonic fibroblasts.

In vivo regulation of precursor cells in the subventricular zone of adult rat brain by thyroid hormone and retinoids

Inflammation severely alters thyroid hormone signaling in the central nervous system during experimental allergic encephalomyelitis in rat: Direct impact on OPCs differentiation failure.

Inhibin and activin in human fetal membranes: evidence for a local effect on prostaglandin release.

Intravitreal NGF administration counteracts retina degeneration after permanent carotid artery occlusion in rat.

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

Multiple neurochemical action of clozapine: A quantitative autoradiographic study of DA 2, opiate and benzodiazepine receptors in the rat brain after long-term treatment ⬇️

Muscarinic and gamma-aminobutyric acid-ergic receptor changes during vestibular compensation. A quantitative autoradiographic study of the vestibular nuclei complex in the rat

NGF content and expression in the rat pituitary gland and regulation by thyroid hormone ⬇️

Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors.

Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.

Neuroprotection and aging of the cholinergic system: a role for the ergoline derivative nicergoline (Sermion).

Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture.

Opiate receptor modifications in the rat brain after chronic treatment with haloperidol and suipiride.

PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects.

Plasticity of GABA(a) system during ageing: focus on vestibular compensation and possible pharmacological intervention.

Prenatal glucocorticoid exposure affects learning and vulnerability of cholinergic neurons.

Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: In vivo evidence of a role for nerve growth factor ⬇️

Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer's and other neurodegenerative diseases

Regulation of VIP mRNA expression by thyroid hormone in different brain areas of adult rat

Response of hypothalamic peptide mRNAs to thyroidectomy

Role of the Thyroid System in Myelination and Neural Connectivity.

Sexual impotence is associated with a reduced production of oxytocin and with an increased production of opioid peptides in the paraventricular nucleus of male rats.

Spinal motoneurone distress during experimental allergic encephalomyelitis.

Stress promotes major changes in dopamine receptor densities within the mesoaccumbens and nigrostriatal systems.

The effect of oxytocin on feeding, drinking, and male copulatory behavior is not diminished by neonatal monosodium glutamate

The role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cells

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair

Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis

Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease

Thyroid hormone and remyelination in adult central nervous system: a lesson from an inflammatory-demyelinating disease

Thyroid hormone and retinoids affect motoneuron phenotype and reaction after axotomy in the spinal cord of adult rats.

Thyroid hormone participates in the regulation of neural stem cells and oligodendrocyte precursor cells in the central nervous system of adult rat.

Thyroid hormone regulates NGF content and p75LNGFR expression in the basal forebrain of adult rats

Thyroid hormone-induced plasticity in the adult rat brain.

Time-course changes of nerve growth factor, corticotropin-releasing hormone, and nitric oxide synthase isoforms and their possible role in the development of inflammatory response in experimental allergic encephalomyelitis.

Triiodothyronine administration ameliorates the demyelination/remyelination ratio in a non-human primate model of multiple sclerosis by correcting tissue hypothyroidism.

Ultra-low-level laser therapy.

Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.

[1-13C]Glucose entry in neuronal and astrocytic intermediary metabolism of aged rats. A study of the effects of nicergoline treatment by 13C NMR spectroscopy.

p75(NTR)-immunoreactivity in the subventricular zone of adult male rats: expression by cycling cells.