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List of works by Francoise Lenfant

Absence of imprinting of HLA class Ia genes leads to co-expression of biparental alleles on term human trophoblast cells upon IFN-gamma induction.

scientific article published in March 1998

Amino acid composition of alpha1/alpha2 domains and cytoplasmic tail of MHC class I molecules determine their susceptibility to human cytomegalovirus US11-mediated down-regulation.

scientific article published on June 2003

Beta-lactamase TEM1 of E. coli. Crystal structure determination at 2.5 A resolution

scientific article

Cardiovascular benefits and risks of testosterone replacement: another warning?

scientific article published in September 2017

Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment

scientific article

Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms.

scientific article

Crystallization and preliminary crystallographic data on Escherichia coli TEM1 beta-lactamase

scientific article

Cutting edge: soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8

scientific article published on 01 June 2000

Determinants of flow-mediated outward remodeling in female rodents: respective roles of age, estrogens, and timing

scientific article

Differential down-modulation of HLA-G and HLA-A2 or -A3 cell surface expression following human cytomegalovirus infection.

scientific article published on June 2004

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

scientific article published on 27 December 2019

Down-regulation of HLA-G1 cell surface expression in human cytomegalovirus infected cells.

scientific article published on October 2003

Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis

scientific article published on 19 June 2018

Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G

scientific article published on 01 December 1997

Endothelial estrogen receptor-alpha plays a crucial role in the atheroprotective action of 17beta-estradiol in low-density lipoprotein receptor-deficient mice.

scientific article published on 7 December 2009

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.

scientific article

Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor α Activation.

scientific article published on 18 August 2017

Estradiol accelerates endothelial healing through the retrograde commitment of uninjured endothelium.

scientific article published on 25 April 2008

Estrogen receptor alpha expression in both endothelium and hematopoietic cells is required for the accelerative effect of estradiol on reendothelialization.

scientific article published on 16 July 2009

Estrogen receptor subcellular localization and cardiometabolism

scientific article published on 16 May 2018

Estrogen receptors and endothelium.

scientific article published on August 2010

Estrogens are needed for the improvement in endothelium-mediated dilation induced by a chronic increase in blood flow in rat mesenteric arteries.

scientific article published on 12 October 2015

FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha.

scientific article

From in vivo gene targeting of oestrogen receptors to optimization of their modulation in menopause.

scientific article published on January 2012

Induction of HLA-G-restricted human cytomegalovirus pp65 (UL83)-specific cytotoxic T lymphocytes in HLA-G transgenic mice.

scientific article published on February 2003

Interferon-gamma rescues HLA class Ia cell surface expression in term villous trophoblast cells by inducing synthesis of TAP proteins

scientific article published on 01 January 1997

Key role of estrogens and endothelial estrogen receptor α in blood flow-mediated remodeling of resistance arteries.

scientific article published on 3 January 2013

Lymph/angiogenesis contributes to sex differences in lung cancer through oestrogen receptor alpha signalling

scientific article published on 01 February 2019

Lymphatic Vasculature Requires ER (Estrogen Receptor)-α Signaling to Protect From Lymphedema.

scientific article published on 12 April 2018

Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice

scientific article published on 01 March 2001

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.

scientific article

Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium

scientific article published on 11 March 2020

Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.

scientific article

Nuclear and Membrane Actions of Estrogen Receptor Alpha: Contribution to the Regulation of Energy and Glucose Homeostasis.

scientific article published in January 2017

Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety

scientific article published on 29 June 2018

Prevention of skin flap necrosis by estradiol involves reperfusion of a protected vascular network.

scientific article

Primary cultured human thymic epithelial cells express both membrane-bound and soluble HLA-G translated products

scientific article published on 01 July 1999

Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α

scientific article

Role for the membrane estrogen receptor alpha in the sexual differentiation of the brain

scientific article published on 13 December 2019

Role of ERαMISS in the Effect of Estradiol on Cancellous and Cortical Femoral Bone in Growing Female Mice

scientific article published on 22 April 2016

Role of estrogens and age in flow-mediated outward remodeling of rat mesenteric resistance arteries

scientific article published in August 2014

Role of inflammatory cytokines in the effect of estradiol on atheroma.

scientific article

SUN-LB001 Estetrol (E4) Is a Unique Estrogen with Selective Actions in Tissues Which Are Distinctly Different from the Actions of SERMs

Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice ⬇️

scientific article published on 29 April 2019

Sex differences in metabolic regulation and diabetes susceptibility

scientific article published on 21 November 2019

Site-directed mutagenesis of beta-lactamase TEM-1. Investigating the potential role of specific residues on the activity of Pseudomonas-specific enzymes

scientific article published on 01 November 1993

Site-directed mutagenesis on TEM-1 ß-lactamase: role of Glul66 in catalysis and substrate binding ⬇️

scientific article published on October 1, 1991

Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells

scientific article published on 29 June 2006

Soluble HLA-G: purification from eukaryotic transfected cells and detection by a specific ELISA.

scientific article published on July 1999

Stromal estrogen receptor-α promotes tumor growth by normalizing an increased angiogenesis.

scientific article

Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions.

scientific article published on 30 March 2017

The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors

scientific article published on 07 December 2016

The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.

scientific article

The full length HLA-G1 and no other alternative form of HLA-G is expressed at the cell surface of transfected cells

scientific article published on 01 March 2000

The interchain disulfide bond between TCR alpha beta heterodimers on human T cells is not required for TCR-CD3 membrane expression and signal transduction

scientific article published on 01 April 1997

The short cytoplasmic tail of HLA-G determines its resistance to HIV-1 Nef-mediated cell surface downregulation.

scientific article

The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol

scientific article

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

scientific article

Therapeutic Benefits and Adverse Effects of Combined Proangiogenic Gene Therapy in Mouse Critical Leg Ischemia

scientific article

Timing of the vascular actions of estrogens in experimental and human studies: why protective early, and not when delayed?

scientific article published on 16 December 2010

Towards optimization of estrogen receptor modulation in medicine

scientific article published on 03 May 2018

Understanding the oestrogen action in experimental and clinical atherosclerosis.

scientific article published on December 2006

[Tissue-specific membrane effects of estrogen receptor alpha]

scientific article published on 16 December 2015

[Towards an optimization of the modulation of the estrogen receptor during menopausal hormonal therapy]

scientific article published on 01 December 2018

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