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List of works by Will Roeffen

A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

scientific article published on 26 February 2015

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

research work

A novel plant-produced Pfs25 fusion subunit vaccine induces long-lasting transmission blocking antibody responses

scientific article published in November 2014

A plant-produced Pfs230 vaccine candidate blocks transmission of Plasmodium falciparum

scientific article

A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice

scientific article

Adherence to Chemoprophylaxis and Plasmodium falciparum Anti-Circumsporozoite Seroconversion in a Prospective Cohort Study of Dutch Short-Term Travelers ⬇️

scientific article published on February 25, 2013

Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity ⬇️

scientific article published on January 1, 2011

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

scientific article

Carbohydrate fatty acid monosulphate esters are safe and effective adjuvants for humoral responses

scientific article published on 4 May 2017

Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

scientific article

Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice

scholarly article

Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies.

scientific article published on 9 April 2007

Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

scientific article published on 23 June 2017

Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings.

scientific article

Mosquito feeding assays to determine the infectiousness of naturally infected Plasmodium falciparum gametocyte carriers

scientific article

Naturally acquired antibody responses to recombinant Pfs230 and Pfs48/45 transmission blocking vaccine candidates

scientific article published on 11 April 2015

Naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs48/45 and Pfs230 in an area of seasonal transmission

scientific article published on 3 October 2011

Plant-produced transmission blocking Plasmodium falciparum Pfs25 subunit and VLP based vaccine candidates.

scientific article published on 15 October 2012

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte

scientific article

Protection against a malaria challenge by sporozoite inoculation

scientific article published on July 2009

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

scientific article published on 18 April 2013

Publisher Correction: Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

scientific article published on 11 April 2018

Rapid onset of transmission-reducing antibodies in javanese migrants exposed to malaria in papua, indonesia

scientific article

Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02.

scientific article

Substantial contribution of submicroscopical Plasmodium falciparum gametocyte carriage to the infectious reservoir in an area of seasonal transmission

scientific article

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

scientific article published on 16 March 2016

The dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in Tanzania

scientific article (publication date: 29 November 2010)

The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria

scientific article

Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants

scientific article

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

scientific article published on 8 February 2018

Variation in susceptibility of African Plasmodium falciparum malaria parasites to TEP1 mediated killing in Anopheles gambiae mosquitoes

scientific article published on 10 February 2016

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