List of works - Christof Geldmacher

A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes

scientific article published on 22 February 2017

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens

scientific article

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

scientific article

Ascaris lumbricoides infection and its relation to environmental factors in the Mbeya region of Tanzania, a cross-sectional, population-based study

scientific article published in 2014

Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study

scientific article

Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

scientific article

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial

scientific article

CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo

scientific article published on 06 July 2016

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

scientific article published on 20 December 2006

Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-γ and Granzyme B and inter- individual variation

scientific article

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

scientific article

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection

scientific article

Early Identification of Progressive TB Disease Using Host Biomarkers

scientific article

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

scientific article published on December 2008

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

scientific article published on 2 August 2016

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

article

Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort

scientific article published on 18 December 2017

First-in-human trial of a live-attenuated Mycobacterium tuberculosis vaccine

scientific article published on 16 November 2015

Helicobacter pylori Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana

scientific article

Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment

scientific article

Hookworm infection and environmental factors in mbeya region, Tanzania: a cross-sectional, population-based study

scientific article

Immune system modulation by helminth infections: potential impact on HIV transmission and disease progression

scientific article published on January 2014

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

scientific article

Interaction between HIV and Mycobacterium tuberculosis

scientific article (publication date: April 2012)

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania

scientific article

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

scientific article published on 14 May 2015

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

scientific article published on 19 June 2009

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

scientific article

Pathogen-specific T cell depletion and reactivation of opportunistic pathogens in HIV infection ⬇️

scientific article published on March 5, 2012

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

scholarly article by Mohamed I M Ahmed et al published 2018 in Frontiers in Immunology

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

scientific article

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

scientific article

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial

scientific article

Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses

article

Reply to Wallis

scientific article published in 2009

Risk factors for HIV-1 infection in a longitudinal, prospective cohort of adults from the Mbeya Region, Tanzania

scientific article

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

scientific article published on 17 April 2007

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol

The TAM-TB Assay-A Promising TB Immune-Diagnostic Test With a Potential for Treatment Monitoring

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study

scientific article

Use of Occult Blood Detection Cards for Real-Time PCR-Based Diagnosis of Schistosoma Mansoni Infection

scientific article published on 11 September 2015

Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania

scientific article

List of works by Christof Geldmacher

A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

Ascaris lumbricoides infection and its relation to environmental factors in the Mbeya region of Tanzania, a cross-sectional, population-based study

Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study

Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial

CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-γ and Granzyme B and inter- individual variation

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection

Early Identification of Progressive TB Disease Using Host Biomarkers

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort

First-in-human trial of a live-attenuated Mycobacterium tuberculosis vaccine

Helicobacter pylori Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana

Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment

Hookworm infection and environmental factors in mbeya region, Tanzania: a cross-sectional, population-based study

Immune system modulation by helminth infections: potential impact on HIV transmission and disease progression

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

Interaction between HIV and Mycobacterium tuberculosis

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

Pathogen-specific T cell depletion and reactivation of opportunistic pathogens in HIV infection ⬇️

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial

Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses

Reply to Wallis

Risk factors for HIV-1 infection in a longitudinal, prospective cohort of adults from the Mbeya Region, Tanzania

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol

The TAM-TB Assay-A Promising TB Immune-Diagnostic Test With a Potential for Treatment Monitoring

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study

Use of Occult Blood Detection Cards for Real-Time PCR-Based Diagnosis of Schistosoma Mansoni Infection

Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania