List of works - Leonard Maboko

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

scientific article

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

scientific article

Ascaris lumbricoides infection and its relation to environmental factors in the Mbeya region of Tanzania, a cross-sectional, population-based study

scientific article published in 2014

Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

scientific article

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial

scientific article

CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo

scientific article published on 06 July 2016

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

scientific article published on 20 December 2006

Class I HLA-A*7401 is associated with protection from HIV-1 acquisition and disease progression in Mbeya, Tanzania

scientific article

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

scientific article published on 13 May 2015

Contraceptive use in women enrolled into preventive HIV vaccine trials: experience from a phase I/II trial in East Africa

scientific article

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article published on 25 September 2017

Correction: Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

scientific article published on 26 August 2016

Decline in sexually transmitted infection prevalence and HIV incidence in female barworkers attending prevention and care services in Mbeya Region, Tanzania

scientific article published on February 2006

Defining the human immunodeficiency virus type 1 transmission genetic bottleneck in a region with multiple circulating subtypes and recombinant forms

scientific article

Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa

scientific article published on 14 November 2014

Differential glycosylation of envelope gp120 affects reactivity with HIV-1 specific antibodies

article

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

scientific article

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

scientific article published on December 2008

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

scientific article published on 2 August 2016

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania

scientific article

Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis

scientific article

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

article

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article

Frequency of HIV type 1 dual infection and HIV diversity: analysis of low- and high-risk populations in Mbeya Region, Tanzania

scientific article published on July 2006

HIV type 1 subtypes among blood donors in the Mbeya region of southwest Tanzania

scientific article

HIV-1 Genetic Diversity Among Incident Infections in Mbeya, Tanzania

scientific article

HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania

scientific article published on September 2005

Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment

scientific article

High seroprevalence for spotted fever group rickettsiae, is associated with higher temperatures and rural environment in Mbeya region, Southwestern Tanzania

scientific article

High seroprevalence for typhus group rickettsiae, southwestern Tanzania

scientific article published on February 2013

High seroprevalence of Rift Valley FEVER AND EVIDENCE FOR ENDEMIC circulation in Mbeya region, Tanzania, in a cross-sectional study

scientific article

High-throughput high-resolution class I HLA genotyping in East Africa

scientific article

Hookworm infection and environmental factors in mbeya region, Tanzania: a cross-sectional, population-based study

scientific article

Implications of storing urinary DNA from different populations for molecular analyses

scientific article

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

scientific article

Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study

scientific article published on 03 April 2012

Laboratory reference values for healthy adults from southern Tanzania

scientific article published on 6 March 2008

Linkage into care among newly diagnosed HIV-positive individuals tested through outreach and facility-based HIV testing models in Mbeya, Tanzania: a prospective mixed-method cohort study

scientific article

Low sensitivity of a urine LAM-ELISA in the diagnosis of pulmonary tuberculosis

scientific article published on 28 August 2009

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania

scientific article

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

scientific article published on 19 June 2009

Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania

scientific article published on 15 January 2007

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

scientific article

Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa

scientific article published on 06 August 2013

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

scientific article

Performance of urine lipoarabinomannan assays for paediatric tuberculosis in Tanzania

scientific article published on 25 June 2015

Possible reasons for an increase in the proportion of genital ulcers due to herpes simplex virus from a cohort of female bar workers in Tanzania

scientific article published on 13 September 2006

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

scientific article

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

scientific article

Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

scientific article

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial

scientific article

Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population

scientific article published on 25 November 2013

Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.

scientific article published on 26 June 2018

Risk factors for HIV-1 infection in a longitudinal, prospective cohort of adults from the Mbeya Region, Tanzania

scientific article

Safety and Immunogenicity of PENNVAX®-G DNA Prime Administered by Biojector® 2000 or CELLECTRA® Electroporation Device with Modified Vaccinia Ankara-CMDR Boost

scientific article published on 2 September 2017

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women

scientific article

Seroprevalence of alphavirus antibodies in a cross-sectional study in southwestern Tanzania suggests endemic circulation of chikungunya

scientific article

Single-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis

scientific article published on September 2005

Thirteen years HIV-1 sentinel surveillance and indicators for behavioural change suggest impact of programme activities in south-west Tanzania

scientific article published on January 2004

Towards host-directed therapies for tuberculosis

scientific article

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study

scientific article

Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania

scientific article

List of works by Leonard Maboko

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

Ascaris lumbricoides infection and its relation to environmental factors in the Mbeya region of Tanzania, a cross-sectional, population-based study

Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial

CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

Class I HLA-A*7401 is associated with protection from HIV-1 acquisition and disease progression in Mbeya, Tanzania

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

Contraceptive use in women enrolled into preventive HIV vaccine trials: experience from a phase I/II trial in East Africa

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

Correction: Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

Decline in sexually transmitted infection prevalence and HIV incidence in female barworkers attending prevention and care services in Mbeya Region, Tanzania

Defining the human immunodeficiency virus type 1 transmission genetic bottleneck in a region with multiple circulating subtypes and recombinant forms

Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa

Differential glycosylation of envelope gp120 affects reactivity with HIV-1 specific antibodies

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania

Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

Frequency of HIV type 1 dual infection and HIV diversity: analysis of low- and high-risk populations in Mbeya Region, Tanzania

HIV type 1 subtypes among blood donors in the Mbeya region of southwest Tanzania

HIV-1 Genetic Diversity Among Incident Infections in Mbeya, Tanzania

HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania

Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment

High seroprevalence for spotted fever group rickettsiae, is associated with higher temperatures and rural environment in Mbeya region, Southwestern Tanzania

High seroprevalence for typhus group rickettsiae, southwestern Tanzania

High seroprevalence of Rift Valley FEVER AND EVIDENCE FOR ENDEMIC circulation in Mbeya region, Tanzania, in a cross-sectional study

High-throughput high-resolution class I HLA genotyping in East Africa

Hookworm infection and environmental factors in mbeya region, Tanzania: a cross-sectional, population-based study

Implications of storing urinary DNA from different populations for molecular analyses

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study

Laboratory reference values for healthy adults from southern Tanzania

Linkage into care among newly diagnosed HIV-positive individuals tested through outreach and facility-based HIV testing models in Mbeya, Tanzania: a prospective mixed-method cohort study

Low sensitivity of a urine LAM-ELISA in the diagnosis of pulmonary tuberculosis

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

Performance of urine lipoarabinomannan assays for paediatric tuberculosis in Tanzania

Possible reasons for an increase in the proportion of genital ulcers due to herpes simplex virus from a cohort of female bar workers in Tanzania

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial

Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population

Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.

Risk factors for HIV-1 infection in a longitudinal, prospective cohort of adults from the Mbeya Region, Tanzania

Safety and Immunogenicity of PENNVAX®-G DNA Prime Administered by Biojector® 2000 or CELLECTRA® Electroporation Device with Modified Vaccinia Ankara-CMDR Boost

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women

Seroprevalence of alphavirus antibodies in a cross-sectional study in southwestern Tanzania suggests endemic circulation of chikungunya

Single-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis

Thirteen years HIV-1 sentinel surveillance and indicators for behavioural change suggest impact of programme activities in south-west Tanzania

Towards host-directed therapies for tuberculosis

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study

Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania