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List of works by Michael Hoelscher

A Phenomenological Account of HIV Disclosure Experiences of Children and Adolescents from Northern and Southern Ghana

article

A Step toward an Optimized Rifampin Dose Completed.

scientific article

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis

scientific article published on May 2015

A high viral burden predicts the loss of CD8 T-cell responses specific for subdominant gag epitopes during chronic human immunodeficiency virus infection

scientific article

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

scientific article

Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test

scientific article published on 24 March 2013

Advancing the development of tuberculosis therapy

scientific article

Ascaris lumbricoides infection and its relation to environmental factors in the Mbeya region of Tanzania, a cross-sectional, population-based study

scientific article published in 2014

Assessment of the Xpert MTB/RIF assay for diagnosis of tuberculosis with gastric lavage aspirates in children in sub-Saharan Africa: a prospective descriptive study

scientific article

Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study

scientific article

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

scientific article published on July 2013

Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort

scientific article

Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial

scientific article

Burden of respiratory tract infections at post mortem in Zambian children

scientific article

Burden of tuberculosis at post mortem in inpatients at a tertiary referral centre in sub-Saharan Africa: a prospective descriptive autopsy study

scientific article

CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo

scientific article published on 06 July 2016

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

scientific article published on 20 December 2006

Class I HLA-A*7401 is associated with protection from HIV-1 acquisition and disease progression in Mbeya, Tanzania

scientific article

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

scientific article published on 13 May 2015

Comparison of Intranasal Outer Membrane Vesicles with Cholera Toxin and Injected MF59C.1 as Adjuvants for Malaria Transmission Blocking Antigens AnAPN1 and Pfs48/45.

scientific article published on 27 April 2016

Comparison of four PCR methods for efficient detection of Trypanosoma cruzi in routine diagnostics

scientific article

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article published on 25 September 2017

Correction: Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

scientific article published on 26 August 2016

Cross-sectional, descriptive study of Chagas disease among citizens of Bolivian origin living in Munich, Germany

scientific article published on 16 January 2017

Decline in sexually transmitted infection prevalence and HIV incidence in female barworkers attending prevention and care services in Mbeya Region, Tanzania

scientific article published on February 2006

Defining the human immunodeficiency virus type 1 transmission genetic bottleneck in a region with multiple circulating subtypes and recombinant forms

scientific article

Detection of HIV-1 subtypes, recombinants, and dual infections in east Africa by a multi-region hybridization assay

scientific article

Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa

scientific article published on 14 November 2014

Differential glycosylation of envelope gp120 affects reactivity with HIV-1 specific antibodies

article

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

scientific article

Direct Comparison of Xpert MTB/RIF Assay with Liquid and Solid Mycobacterial Culture for Quantification of Early Bactericidal Activity

scientific article published on April 17, 2013

Drug resistance and population structure of M.tuberculosis isolates from prisons and communities in Ethiopia

scientific article

Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs

scientific article published on 3 April 2012

Drug-resistant tuberculosis: time for visionary political leadership

scientific article

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

scientific article published on December 2008

Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients

scientific article published on 27 January 2015

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

scientific article published on 2 August 2016

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis

article by Gian Luca Di Tanna et al published February 2019 in The Lancet Global Health

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania

scientific article

Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial

scientific article published on 9 March 2016

Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis

scientific article

Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics

scientific article published on 15 August 2016

Elevated Values of Clinically Relevant Transferases Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 14,559 Diseased German Travelers Returning from the Tropics and Subtropics

scientific article published on 23 May 2016

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

article

Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center

scholarly article by Jia Bainga Kangbai et al published 24 January 2019 in BMC Infectious Diseases

European Union and EDCTP strategy in the global context: Recommendations for preventive HIV/AIDS vaccines research

article

Evaluation of QuantiFERON microtube, using 0.9 mL blood, for diagnosing tuberculosis infection

scientific article published on 9 August 2012

Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort

scientific article published on 18 December 2017

Evaluation of health research capacity strengthening trainings on individual level: validation of a questionnaire

scientific article published on 15 May 2014

Evaluation of the Xpert MTB/RIF assay at a tertiary care referral hospital in a setting where tuberculosis and HIV infection are highly endemic

scientific article

Evaluation of the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting

scientific article published on 14 April 2011

Evaluation of the burden of unsuspected pulmonary tuberculosis and co-morbidity with non-communicable diseases in sputum producing adult inpatients

scientific article

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

scientific article published on 28 October 2013

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article

First report on bla NDM-1-producing Acinetobacter baumannii in three clinical isolates from Ethiopia

scientific article

Frequency of HIV type 1 dual infection and HIV diversity: analysis of low- and high-risk populations in Mbeya Region, Tanzania

scientific article published on July 2006

HIV type 1 subtypes among blood donors in the Mbeya region of southwest Tanzania

scientific article

HIV-1 Genetic Diversity Among Incident Infections in Mbeya, Tanzania

scientific article

HIV-1 diversity and prevalence differ between urban and rural areas in the Mbeya region of Tanzania

scientific article published on September 2005

Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment

scientific article

High seroprevalence for spotted fever group rickettsiae, is associated with higher temperatures and rural environment in Mbeya region, Southwestern Tanzania

scientific article

High seroprevalence for typhus group rickettsiae, southwestern Tanzania

scientific article published on February 2013

High seroprevalence of Rift Valley FEVER AND EVIDENCE FOR ENDEMIC circulation in Mbeya region, Tanzania, in a cross-sectional study

scientific article

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial

scientific article published on 26 October 2016

High-throughput high-resolution class I HLA genotyping in East Africa

scientific article

Hookworm infection and environmental factors in mbeya region, Tanzania: a cross-sectional, population-based study

scientific article

Host-directed therapies for infectious diseases: current status, recent progress, and future prospects

scientific article published on April 2016

Implications of storing urinary DNA from different populations for molecular analyses

scientific article

In a mixed subtype epidemic, the HIV-1 Gag-specific T-cell response is biased towards the infecting subtype

scientific article

Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study

scientific article published on 03 April 2012

Interaction between HIV and Mycobacterium tuberculosis

scientific article (publication date: April 2012)

In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation

scientific article published on 18 January 2017

Laboratory reference values for healthy adults from southern Tanzania

scientific article published on 6 March 2008

Limited value of whole blood Xpert(®) MTB/RIF for diagnosing tuberculosis in children

scientific article published on 6 July 2016

Long-term kinetics of Zika virus RNA and antibodies in body fluids of a vasectomized traveller returning from Martinique: a case report

scientific article (publication date: 10 January 2017)

Low sensitivity of a urine LAM-ELISA in the diagnosis of pulmonary tuberculosis

scientific article published on 28 August 2009

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania

scientific article

Lymphocytosis and Lymphopenia Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 17,229 Diseased German Travelers Returning from the Tropics and Subtropics

scientific article published on 11 April 2016

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

scientific article published on 14 May 2015

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

scientific article published on 19 June 2009

Modifying the multi-arm multi-stage (MAMS) design for use in a phase II tuberculosis trial in sub-Saharan Africa with a time-to-event primary outcome

scientific article published on 29 November 2013

Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania

scientific article published on 15 January 2007

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

scientific article

Morbidity profile and sociodemographic characteristics of unaccompanied refugee minors seen by paediatric practices between October 2014 and February 2016 in Bavaria, Germany

article

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

scientific article published on 31 October 2016

Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa

scientific article published on 06 August 2013

New and improved diagnostics for detection of drug-resistant pulmonary tuberculosis

scientific article published on May 2011

New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects

scientific article published on April 2014

New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future

scientific article published on 22 March 2012

Non-tuberculous mycobacteria

scientific article published on 5 March 2010

O-5S quantitative real-time PCR: a new diagnostic tool for laboratory confirmation of human onchocerciasis

scientific article published on 2 October 2017

Operational feasibility of using loop-mediated isothermal amplification for diagnosis of pulmonary tuberculosis in microscopy centers of developing countries

scientific article published on 28 March 2007

Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3

scientific article published on 31 May 2022

Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment

scientific article

Performance of urine lipoarabinomannan assays for paediatric tuberculosis in Tanzania

scientific article published on 25 June 2015

Period prevalence and identification challenges of viral haemorrhagic fever suspect cases in a tertiary referral hospital in Guinea: a cross-sectional, retrospective study of triage and emergency room patient profiles

scientific article published on 12 November 2020

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

scholarly article by Mohamed I M Ahmed et al published 2018 in Frontiers in Immunology

Plasmodium knowlesi infection in a returning German traveller from Thailand: a case report on an emerging malaria pathogen in a popular low-risk travel destination.

scientific article

Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model

scientific article published on 11 February 2021

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

scientific article

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

scientific article

Prevalence and antibiotic susceptibility pattern of CTX-M type extended-spectrum β-lactamases among clinical isolates of gram-negative bacilli in Jimma, Ethiopia

scientific article

Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania

scientific article

Prevalence of Pulmonary Tuberculosis among Prison Inmates in Ethiopia, a Cross-Sectional Study

scientific article published on 7 December 2015

Prevalence of Rickettsia species in ticks including identification of unknown species in two regions in Kazakhstan

scholarly article published by Michael Hoelscher in 2019

Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial

scientific article

Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study

scientific article published on July 2015

QuantiFERON®-TB gold in-tube performance for diagnosing active tuberculosis in children and adults in a high burden setting

scientific article (publication date: 2012)

Rapid and accurate detection of Mycobacterium tuberculosis in sputum samples by Cepheid Xpert MTB/RIF assay--a clinical validation study

scientific article

Rapid molecular detection of tuberculosis.

scientific article

Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population

scientific article published on 25 November 2013

Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants.

scientific article published on 26 June 2018

Reply to Dodd and Proschan

scientific article published on 21 November 2012

Reply to Wallis

scientific article published in 2009

Retention in care and reasons for discontinuation of lifelong antiretroviral therapy in a cohort of Cameroonian pregnant and breastfeeding HIV-positive women initiating 'Option B+' in the South West Region

scientific article published on 16 November 2016

Retrospective clinical case series study in 2017 identifies as most frequent species in returning travellers from Thailand to Germany

article

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa

scientific article published on 10 June 2010

Risk factors for HIV-1 infection in a longitudinal, prospective cohort of adults from the Mbeya Region, Tanzania

scientific article

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women

scientific article

Seroprevalence of alphavirus antibodies in a cross-sectional study in southwestern Tanzania suggests endemic circulation of chikungunya

scientific article

Similar trends of susceptibility in Anopheles arabiensis and Anopheles pharoensis to Plasmodium vivax infection in Ethiopia

scientific article (publication date: 18 October 2016)

Single-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis

scientific article published on September 2005

Stability of gametocyte-specific Pfs25-mRNA in dried blood spots on filter paper subjected to different storage conditions

scientific article published on 30 April 2012

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol

Test characteristics and potential impact of the urine LAM lateral flow assay in HIV-infected outpatients under investigation for TB and able to self-expectorate sputum for diagnostic testing

scientific article published on 9 July 2015

The impact of repeated NALC/NaOH- decontamination on the performance of Xpert MTB/RIF assay.

scientific article

The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment

scientific article

Towards host-directed therapies for tuberculosis

scientific article

Trichuris trichiura infection and its relation to environmental factors in Mbeya region, Tanzania: A cross-sectional, population-based study

scientific article

Tuberculosis and tuberculosis/HIV/AIDS-associated mortality in Africa: the urgent need to expand and invest in routine and research autopsies

scientific article

Tuberculosis at post-mortem in inpatient adults at a tertiary referral centre in sub-Saharan Africa – A prospective descriptive autopsy study

scientific article published in 2015

Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts

scientific article published on 24 March 2013

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

scientific article published on 10 April 2012

Tuberculosis in association with HIV/AIDS emerges as a major nonobstetric cause of maternal mortality in Sub-Saharan Africa

scientific article published on 13 January 2010

Tuberculosis in prisons in sub-Saharan Africa--the need for improved health services, surveillance and control

scientific article published on 20 January 2011

Tuberculosis treatment and management--an update on treatment regimens, trials, new drugs, and adjunct therapies

scientific article published on 09 March 2015

Tuberculosis--advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers

scientific article published on April 2016

Uptake and performance of prevention of mother-to-child transmission and early infant diagnosis in pregnant HIV-infected women and their exposed infants at seven health centres in Addis Ababa, Ethiopia

scientific article published on 13 April 2017

Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments

scientific article

Viewpoint: Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infection

scientific article

Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania

scientific article

Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire

scientific article published on 08 December 2016

Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

scientific article

World TB Day 2016: reflections on the global TB emergency

scientific article published on 16 March 2016