List of works - Sasisekhar Bennuru

1790Targeting filarial kinases with human homologues: repurposed, orally available, approved tyrosine kinase inhibitors (TKI) act as micro- and macrofilaricidal agents at concentrations easily achievable in vivo

scientific article published in December 2014

A Proteomic Analysis of the Body Wall, Digestive Tract, and Reproductive Tract of Brugia malayi

scientific article

Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling

scientific article

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum

article

Discovery of Specific Antigens That Can Predict Microfilarial Intensity in Loa loa Infection

scientific article

Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections

scientific article

Helminth infection alters IgE responses to allergens structurally related to parasite proteins

scientific article

Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection

scientific article

Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

scientific article published on January 2015

Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping

scientific article published on September 2017

Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis

scientific article

Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling

scientific article

Metabolite profiling of infection-associated metabolic markers of onchocerciasis

scientific article published on 7 February 2017

Microfilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic Cells

scientific article published on 13 June 2016

Mining Filarial Genomes for Diagnostic and Therapeutic Targets

scientific article published on 11 October 2017

Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization ⬇️

scientific article published on April 25, 2012

Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope

scientific article published on May 2015

Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion

scientific article published on 19 February 2013

Repurposed automated handheld counter as a point-of-care tool to identify individuals 'at risk' of serious post-ivermectin encephalopathy

scientific article (publication date: September 2014)

Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.

scientific article

Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis

scientific article

Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont

scientific article

Stage-specific proteomic expression patterns of the human filarial parasiteBrugia malayiand its endosymbiontWolbachia ⬇️

scientific article published on May 23, 2011

Structural Differences between Human Proteins and Aero- and Microbial Allergens Define Allergenicity ⬇️

scientific article published on July 18, 2012

Structural and immunologic cross-reactivity among filarial and mite tropomyosin: Implications for the hygiene hypothesis ⬇️

scientific article published on December 24, 2010

Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal

scientific article

The genome of Onchocerca volvulus, agent of river blindness

scientific article published on 21 November 2016

Understanding Hidden Antigens and Targeting Parasitic Nematodes

scientific article published on 14 September 2015

List of works by Sasisekhar Bennuru

1790Targeting filarial kinases with human homologues: repurposed, orally available, approved tyrosine kinase inhibitors (TKI) act as micro- and macrofilaricidal agents at concentrations easily achievable in vivo

A Proteomic Analysis of the Body Wall, Digestive Tract, and Reproductive Tract of Brugia malayi

Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum

Discovery of Specific Antigens That Can Predict Microfilarial Intensity in Loa loa Infection

Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections

Helminth infection alters IgE responses to allergens structurally related to parasite proteins

Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection

Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping

Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis

Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling

Metabolite profiling of infection-associated metabolic markers of onchocerciasis

Microfilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic Cells

Mining Filarial Genomes for Diagnostic and Therapeutic Targets

Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization ⬇️

Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope

Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion

Repurposed automated handheld counter as a point-of-care tool to identify individuals 'at risk' of serious post-ivermectin encephalopathy

Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.

Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis

Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont

Stage-specific proteomic expression patterns of the human filarial parasiteBrugia malayiand its endosymbiontWolbachia ⬇️

Structural Differences between Human Proteins and Aero- and Microbial Allergens Define Allergenicity ⬇️

Structural and immunologic cross-reactivity among filarial and mite tropomyosin: Implications for the hygiene hypothesis ⬇️

Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal

The genome of Onchocerca volvulus, agent of river blindness

Understanding Hidden Antigens and Targeting Parasitic Nematodes