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List of works by Elaine Bignell

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.

scientific article

A new and clinically relevant murine model of solid-organ transplant aspergillosis.

scientific article published on 20 December 2012

Abstracts from the 3rd International Severe Asthma Forum (ISAF).

scientific article

Ambient pH gene regulation in fungi: making connections.

scientific article published on 03 May 2008

Amino acid biosynthetic routes as drug targets for pulmonary fungal pathogens: what is known and why do we need to know more?

scientific article published on 22 July 2016

Anti-Aspergillus Activities of the Respiratory Epithelium in Health and Disease

scientific article published on 8 January 2018

Candida glabrata STE12 is required for wild-type levels of virulence and nitrogen starvation induced filamentation

scientific article published on 01 November 2003

Candida glabrata Ste11 is involved in adaptation to hypertonic stress, maintenance of wild-type levels of filamentation and plays a role in virulence.

scientific article published in June 2005

Candida glabrata Ste20 is involved in maintaining cell wall integrity and adaptation to hypertonic stress, and is required for wild-type levels of virulence.

scientific article published in May 2004

Conservation in Aspergillus fumigatus of pH‐signaling seven transmembrane domain and arrestin proteins, and implications for drug discovery ⬇️

scientific article published on December 1, 2012

Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. ⬇️

scientific article published on 18 June 2015

Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus

scientific article

Distribution, expression and expansion of Aspergillus fumigatus LINE-like retrotransposon populations in clinical and environmental isolates.

scientific article published on 15 January 2014

Editorial overview: The fungal infection arena in animal and plant hosts: dynamics at the interface

scientific article published on 12 July 2016

Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies.

scientific article published in May 2010

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.

scientific article published on 20 February 2008

Host-fungal interactions: key players of antifungal immunity.

scientific article published in February 2012

Impaired Interferon‐γ Responses, Increased Interleukin‐17 Expression, and a Tumor Necrosis Factor–α Transcriptional Program in Invasive Aspergillosis

scientific article published on 15 October 2009

In silico modeling of spore inhalation reveals fungal persistence following low dose exposure

scientific article published on 14 September 2015

Incidence of dsRNA mycoviruses in a collection of Aspergillus fumigatus isolates.

scientific article published on 20 May 2012

Microbial uptake by the respiratory epithelium: outcomes for host and pathogen

scientific article published on 01 March 2019

Mutual independence of alkaline- and calcium-mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus

scientific article published on 18 September 2017

Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence.

scientific article

On the Determination of the Stereochemistry of Semisynthetic Natural Product Analogues using Chiroptical Spectroscopy: Desulfurization of Epidithiodioxopiperazine Fungal Metabolites

scientific article published on 05 September 2011

On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

scientific article published on 25 October 2013

Receptor-mediated signaling in Aspergillus fumigatus.

scientific article published on 20 February 2013

Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein

scientific article

Secondary metabolite arsenal of an opportunistic pathogenic fungus.

scientific article

Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence ⬇️

scientific article

Sub-telomere directed gene expression during initiation of invasive aspergillosis

scientific article

Tackling the emerging threat of antifungal resistance to human health

scientific article published in September 2022

The Aspergillus pH-responsive transcription factor PacC regulates virulence.

scientific article published in February 2005

The Molecular Basis of pH Sensing, Signaling, and Homeostasis in Fungi

scientific article published on January 1, 2012

The effects of dsRNA mycoviruses on growth and murine virulence of Aspergillus fumigatus

article

The host-infecting fungal transcriptome.

scientific article published on June 2010

The mechanistic basis of pH-dependent 5-flucytosine resistance in Aspergillus fumigatus.

scientific article published on 2 April 2018

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis ⬇️

scientific article (publication date: October 2014)

Therapeutic jackpots lie within the reach of multiscale and integrated mycological research.

scientific article published in December 2010

Transcript levels of the Aspergillus fumigatus Cdc42 module, polarisome, and septin genes show little change from dormancy to polarity establishment.

scientific article published in June 2017

Two new genes involved in signalling ambient pH in Aspergillus nidulans

article

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

scientific article

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