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List of works by Mercedes Gonzalez-Juarrero

Animal models of M. tuberculosis Infection

scientific article published on 01 November 2007

Cell mediated immune response in goats after experimental challenge with the virulent Brucella melitensis strain 16M and the reduced virulence strain Rev. 1

scientific article published on 18 June 2018

Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice

scientific article published on 31 December 2018

Correlates of immune protection following cutaneous immunization with an attenuated Burkholderia pseudomallei vaccine.

scientific article published on 07 October 2013

Cross-reaction of anti-human CD monoclonal antibodies on guinea pig cells: a summary of the guinea pig section of the HLDA8 animal homologues data.

scientific article

Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599

scientific article published on 18 July 2019

Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation.

scientific article

Direct Inhibition of MmpL3 by Novel Antitubercular Compounds

scientific article published on 28 March 2019

Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection

article

Dynamics of macrophage cell populations during murine pulmonary tuberculosis

scientific article published on 01 September 2003

Enhanced macrophage activity in granulomatous lesions of immune mice challenged with Mycobacterium tuberculosis

scientific article published on 01 April 2006

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

scientific article published on 28 June 2018

Extended culture of macrophages from different sources and maturation results in a common M2 phenotype.

scientific article published on 27 February 2015

Factors associated with severe granulomatous pneumonia in Mycobacterium tuberculosis-infected mice vaccinated therapeutically with hsp65 DNA.

scientific article

Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapoptotic markers of the TNF receptor-associated factor family

scientific article published on 01 September 2005

GM-CSF knockout mice for preclinical testing of agents with antimicrobial activity against Mycobacterium abscessus.

scientific article published on 11 November 2013

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

scientific article

Host Directed Therapy for Chronic Tuberculosis via Intrapulmonary Delivery of Aerosolized Peptide Inhibitors Targeting the IL-10-STAT3 Pathway

scientific article published in Scientific Reports

Immune response to Mycobacterium tuberculosis and identification of molecular markers of disease.

scientific article published on 11 September 2008

Immunity to TB and Targets for Immunotherapy ⬇️

scientific article published on February 1, 2012

In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL/6 mice.

scientific article published in December 2002

Interactions of free-living amoebae with rice bacterial pathogens Xanthomonas oryzae pathovars oryzae and oryzicola

scientific article published in PLoS ONE

Interleukin-10 production by lung macrophages in CBA xid mutant mice infected with Mycobacterium tuberculosis

scientific article published on 01 June 2005

Interleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J mice

scientific article published on October 2008

Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis

scientific article published on 18 December 2008

Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection.

scientific article published on 12 February 2009

Local pulmonary immunotherapy with siRNA targeting TGFβ1 enhances antimicrobial capacity in Mycobacterium tuberculosis infected mice

scientific article published on 31 December 2010

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts

scientific article (publication date: December 2014)

Microhemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice

scientific article published on 24 June 2014

Minipigs as a neonatal animal model for tuberculosis vaccine efficacy testing

scientific article published on 26 July 2019

Modulation of splenic macrophages, and swine leukocyte antigen (SLA) and viral antigen expression following African swine fever virus (ASFV) inoculation

scientific article published on January 1, 1992

Mycobacterium bovis hosted by free-living-amoebae permits their long-term persistence survival outside of host mammalian cells and remain capable of transmitting disease to mice.

scientific article published on 5 June 2017

Neonatal and infant immunity for tuberculosis vaccine development: importance of age-matched animal models

scientific article published on 15 September 2020

Non-surgical Intratracheal Instillation of Mice with Analysis of Lungs and Lung Draining Lymph Nodes by Flow Cytometry ⬇️

scientific article published on May 2, 2011

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

scientific article published on 20 September 2018

Optimization of inhaled therapies for tuberculosis: The role of macrophages and dendritic cells ⬇️

scientific article published on January 1, 2011

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

scientific journal article

Phenotypic non-equivalence of murine (monocyte-) macrophage cells in biomaterial and inflammatory models

scientific article published on 01 March 2009

Polar lipids of Burkholderia pseudomallei induce different host immune responses

scientific article

Porcine lymphocyte gamma interferon responses to mitogenic stimuli monitored by a direct immunoassay

scientific article published on 01 March 1994

Potential and development of inhaled RNAi therapeutics for the treatment of pulmonary tuberculosis

scientific article published on 21 April 2016

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

scientific article published on 30 March 2015

Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular

article

Reduced in vitro immune response on titania nanotube arrays compared to titanium surface

scientific article published on 28 November 2012

Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis

scientific article published on 01 April 2008

Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with Mycobacterium tuberculosis.

scientific article

Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies

scientific article published on 06 June 2019

Swine leukocyte antigen and macrophage marker expression on both African swine fever virus-infected and non-infected primary porcine macrophage cultures ⬇️

scientific article published on May 1, 1992

Temporal and spatial arrangement of lymphocytes within lung granulomas induced by aerosol infection with Mycobacterium tuberculosis.

scientific article

The minipig as an animal model to study Mycobacterium tuberculosis infection and natural transmission.

scientific article published on 14 July 2017

The progression of chronic tuberculosis in the mouse does not require the participation of B lymphocytes or interleukin-4

scientific article published on 01 March 2001

Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3

scientific article published on 13 June 2016

Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages.

scientific article

XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-γ by CD4 T cells and participates in granuloma stability

scientific article published on 15 August 2007

Yersinia pestis Survival and Replication in Potential Ameba Reservoir.

scientific article published in February 2018

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