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List of works by Maria Chiara Bonini

A CD8α- Subset of CD4+ SLAMF7+ Cytotoxic T Cells is Expanded in Patients with IgG4-Related Disease and Decreases following Glucocorticoid Treatment.

scientific article published on 2 March 2018

A dual role for genetically modified lymphocytes in cancer immunotherapy.

scientific article published on 07 January 2012

Adoptive T-cell therapy for cancer: The era of engineered T cells

scientific article (publication date: September 2015)

Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation

scientific article published on January 2014

Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

scientific article published on 07 March 2014

Antitumor effects of HSV-TK engineered donor lymphocytes after allogeneic stem-cell transplantation

scientific article published on 27 February 2007

Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting

scientific article published on 07 December 2018

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

scientific article published on 25 March 2019

CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade

scientific article published on 05 March 2020

Cell-based strategies to manage leukemia relapse: efficacy and feasibility of immunotherapy approaches

scientific article

Changes in T-cell responses against human herpesvirus-8 correlate with the disease course of iatrogenic Kaposi's sarcoma in a patient with undifferentiated arthritis.

scientific article published on 17 July 2008

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

scientific article published on 18 December 2018

Clinical pharmacology of CAR-T cells: Linking cellular pharmacodynamics to pharmacokinetics and antitumor effects.

scientific article

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Tran

scientific article published on 15 May 2019

Concomitant Tumor and Minor Histocompatibility Antigen–Specific Immunity Initiate Rejection and Maintain Remission from Established Spontaneous Solid Tumors

scientific article published on 13 April 2010

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

scientific article

Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition

scientific article

Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors

scientific article published on 27 August 2019

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

scientific article published on January 2006

Early molecular diagnosis of aspergillosis in a patient with acute myeloid leukaemia

scientific article

Early recovery of CMV immunity after HLA-haploidentical hematopoietic stem cell transplantation as a surrogate biomarker for a reduced risk of severe infections overall

scientific article published on 15 June 2015

Expression of HSV-TK suicide gene in primary T lymphocytes: the dog as a preclinical model.

scientific article published on March 2000

Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation.

scientific article published on 20 July 2007

Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation.

scientific article published on 3 March 2015

Genetic engineering of T cells for the immunotherapy of haematological malignancies.

scientific article published on January 2012

Genetic modification of T cells

scientific article

Genetically Modified Donor Leukocyte Transfusion and Graft-Versus-Leukemia Effect After Allogeneic Stem Cell Transplantation ⬇️

scientific article published on March 30, 2011

Genomic loss of patient-specific HLA in acute myeloid leukemia relapse after well-matched unrelated donor HSCT.

scientific article published in May 2012

Handling, processing and disposal of stem cell products in Europe: A survey by the cellular therapy and immunobiology working party of the European Society for Blood and Marrow Transplantation

scientific article published on 15 January 2018

Haploidentical HSCT: a 15-year experience at San Raffaele.

scientific article published in June 2015

Hematopoietic SCT in Europe 2013: recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants.

scientific article

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually.

scientific article published on 22 February 2016

Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies.

scientific article published in April 2018

Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors ⬇️

scientific article published on October 10, 1998

Human Herpesvirus 6 Infection Following Haploidentical Transplantation: Immune Recovery and Outcome.

scientific article published on 30 September 2016

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

scientific article published on 15 November 2012

IL-7 receptor expression identifies suicide gene–modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors ⬇️

scientific article published on April 29, 2011

Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP.

scientific article published on 17 April 2018

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

scientific article published on 25 March 2019

Immunotherapy of human viral and malignant diseases with genetically modified T-cell clones.

scientific article published in May 2000

Impact of drug development on the use of stem cell transplantation: a report by the European Society for Blood and Marrow Transplantation (EBMT).

scientific article published on 7 November 2016

Improving the safety of cell therapy with the TK-suicide gene

scientific article

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

scientific article published on February 2015

Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation.

scientific article published on 5 November 2014

Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019.

scientific article

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD

scientific article

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

scientific article published in April 2009

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

scientific article

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

scientific article

Lentivirus-Induced Dendritic Cells for Immunization Against High-Risk WT1+ Acute Myeloid Leukemia ⬇️

scientific article published on February 1, 2013

Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-TK transduced T-cells.

scientific article published on 23 April 2015

Loss of mismatched HLA in leukemia after stem-cell transplantation.

scientific article

Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation

scientific article published on 20 July 2018

Missing HLA C group 1 ligand in patients with AML and MDS is associated with reduced risk of relapse and better survival after allogeneic stem cell transplantation with fludarabine and treosulfan reduced toxicity conditioning.

scientific article published on 19 June 2017

Modulation of GvHD by suicide-gene transduced donor T lymphocytes: clinical applications in mismatched transplantation.

scientific article

Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses.

scientific article

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

scientific article published on 28 May 2018

NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications.

scientific article

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

scientific article

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

scientific article published in February 2018

Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer.

scientific article published on April 1994

Post-transplantation Cyclophosphamide and Sirolimus after Haploidentical Hematopoietic Stem Cell Transplantation Using a Treosulfan-based Myeloablative Conditioning and Peripheral Blood Stem Cells

scientific article published on 19 May 2015

Potential and limitations of HSV-TK-transduced donor peripheral blood lymphocytes after allo-BMT

scientific article published on 01 October 1997

Predicting the Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation: The Long and Winding Road toward Validated Immune Biomarkers.

scientific article published on 25 March 2013

Prevention and treatment of relapse after stem cell transplantation by cellular therapies

scientific article published on 24 May 2018

Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium - HAPLO2016, San Diego, California, December 1, 2016.

scientific article published on 12 January 2018

Restoring Natural Killer Cell Immunity against Multiple Myeloma in the Era of New Drugs.

scientific article published on 7 November 2017

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

scholarly article

Safety of retroviral gene marking with a truncated NGF receptor

scientific article published on 01 April 2003

Secondary malignancies after high-dose chemotherapy in germ cell tumor patients: a 34-year retrospective study of the European Society for Blood and Marrow Transplantation (EBMT).

scientific article

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

scientific article published on 4 June 2014

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

scientific article published on 21 August 2011

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

Suicide Gene Transduced T‐cells for the Regulation of the Graft‐versus‐Leukemia Effect ⬇️

scientific article published on January 1, 1998

T memory stem cells in health and disease.

scientific article published on January 2017

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation.

scientific article

Targeted genome editing in human repopulating haematopoietic stem cells

scientific article published on 28 May 2014

Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation.

scientific article

The hidden (and lazy) TCR

scientific article published on 01 October 2009

Therapeutic and diagnostic applications of minor histocompatibility antigen HA-1 and HA-2 disparities in allogeneic hematopoietic stem cell transplantation: a survey of different populations.

scientific article published in January 2006

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

scientific article

Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design.

scientific article published on 17 March 2009

Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes.

scientific article published on May 2004

Trick to treat: tricking the thymus to treat cancer.

scientific article published in July 2013

Use of TK-cells in haploidentical hematopoietic stem cell transplantation.

scientific article

Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report.

scientific article

When transgenes shape immunity: cancer immune-gene therapy.

scientific article

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