List of works by Issaka Sagara

"Spatial heterogeneity of environmental risk in randomized prevention trials: consequences and modeling"

scientific article published on 15 July 2019

A Phase 3, Double-Blind, Randomized Study of Arterolane Maleate-Piperaquine Phosphate vs Artemether-Lumefantrine for Falciparum Malaria in Adolescent and Adult Patients in Asia and Africa

scientific article published on 21 February 2016

A high malaria reinfection rate in children and young adults living under a low entomological inoculation rate in a periurban area of Bamako, Mali

scientific article

A multi-center, open-label trial to compare the efficacy and pharmacokinetics of Artemether-Lumefantrine in children with severe acute malnutrition versus children without severe acute malnutrition: study protocol for the MAL-NUT study

scientific article published on 12 June 2015

A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults

scientific article

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

scientific article published on 25 March 2009

A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

scientific article

A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.

scientific article published in October 2006

A randomized trial of dihydroartemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali

scientific article published on 05 October 2018

Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine

scientific article

Analyzing Deoxyribose Nucleic Acid from Malaria Rapid Diagnostic Tests to Study Plasmodium falciparum Genetic Diversity in Mali

scientific article

Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing

scientific article published on 13 October 2020

Assessment of Efficacy and Safety of Arterolane Maleate-Piperaquine Phosphate Dispersible Tablets in Comparison With Artemether-Lumefantrine Dispersible Tablets in Pediatric Patients With Acute Uncomplicated Plasmodium falciparum Malaria: A Phase 3,

scientific article published on 29 August 2017

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis

scientific article

Blood stage vaccines for Plasmodium falciparum: current status and the way forward

scientific article

Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: a modelling and simulation analysis.

scientific article

Comparing the understanding of subjects receiving a candidate malaria vaccine in the United States and Mali

scientific article

Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study

scientific article

Delayed anemia assessment in patients treated with oral artemisinin derivatives for uncomplicated malaria: a pooled analysis of clinical trials data from Mali

scientific article

Different Plasmodium falciparum clearance times in two Malian villages following artesunate monotherapy

scientific article published on 19 April 2020

Differential infectivity of gametocytes after artemisinin-based combination therapy of uncomplicated falciparum malaria

scientific article published on 06 December 2018

Dispersible formulation of artemether/lumefantrine: specifically developed for infants and young children

scientific article published on 12 October 2009

Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention

scientific article published on 30 January 2019

Effect of Adding Azithromycin to the Antimalarials used for Seasonal Malaria Chemoprevention on the Nutritional Status of African Children

scientific article published on 12 March 2020

Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults

scientific article

Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial

scientific article published on 14 April 2009

Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial

scientific article

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

scientific article published on 23 August 2009

Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali

scientific article published on 26 February 2009

Efficacy of sulphadoxine-pyrimethamine + artesunate, sulphadoxine-pyrimethamine + amodiaquine, and sulphadoxine-pyrimethamine alone in uncomplicated falciparum malaria in Mali

scientific article

Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali

scientific article published on March 2008

Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: Secondary analysis of a household-randomised, placebo-controlled trial in Houndé District, Burkina Faso and Bougouni District, Mali

scientific article published on 21 August 2020

Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method

scientific article published in Scientific Reports

False-negative rapid diagnostic tests for malaria and deletion of the histidine-rich repeat region of the hrp2 gene

scientific article published on February 2012

Gametocyte clearance dynamics following oral artesunate treatment of uncomplicated falciparum malaria in Malian children

scientific article

Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013-2017

scientific article published on 04 June 2020

Haematological and Biochemical Reference Values for Healthy Population of Maferinyah Rural Community in Guinea

scientific article published on 03 August 2020

Hemoglobin variants shape the distribution of malaria parasites in human populations and their transmission potential

scientific article published on 27 October 2017

Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized

scientific article

Impact of Three-Year Intermittent Preventive Treatment Using Artemisinin-Based Combination Therapies on Malaria Morbidity in Malian Schoolchildren

scientific article published on 17 September 2020

Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians

scientific article

Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali

scientific article published on 8 July 2008

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

scientific article published on 03 March 2020

Impact of the addition of azithromycin to antimalarials used for seasonal malaria chemoprevention on antimicrobial resistance of Streptococcus pneumoniae

scientific article published on 13 November 2019

In Vivo Efficacy and Parasite Clearance of Artesunate + Sulfadoxine-Pyrimethamine Versus Artemether-Lumefantrine in Mali

scientific article published on 25 January 2016

Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali: results from a cluster randomized control trial

scientific article

Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine

scientific article

Malaria Infection and Gametocyte Carriage Rates in Preparation for Transmission Blocking Vaccine Trials in Bancoumana, Mali

scientific article published in July 2017

Malaria incidence in relation to rice cultivation in the irrigated Sahel of Mali

scientific article published on January 2004

Marked Rise in the Prevalence of Asymptomatic Plasmodium falciparum Infection in Rural Gabon

scientific article

Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali

scientific article published on 10 August 2017

Modelling recurrent events: comparison of statistical models with continuous and discontinuous risk intervals on recurrent malaria episodes data

scientific article

Molecular Detection of Microorganisms Associated with Small Mammals and Their Ectoparasites in Mali

scientific article published on 02 November 2020

Molecular markers of resistance to sulphadoxine-pyrimethamine one year after implementation of intermittent preventive treatment of malaria in infants in Mali

scientific article

No evidence of delayed parasite clearance after oral artesunate treatment of uncomplicated falciparum malaria in Mali

scientific article

Non-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay

scientific article

Optimal mode for delivery of seasonal malaria chemoprevention in Ouelessebougou, Mali: A cluster randomized trial.

scientific article published on 5 March 2018

Optimizing Direct Membrane and Direct Skin Feeding Assays for Plasmodium falciparum Transmission-Blocking Vaccine Trials in Bancoumana, Mali

scientific article published on 26 June 2017

Pharmacovigilance of malaria intermittent preventive treatment in infants coupled with routine immunizations in 6 african countries

scientific article published on March 2012

Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara

scientific article published on 30 August 2016

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children

scientific article

Plasmodium falciparum Plasmepsin 2 Duplications, West Africa

scientific article published in 2018

Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali

scientific article

Polymorphisms in the K13-propeller gene in artemisinin-susceptible Plasmodium falciparum parasites from Bougoula-Hameau and Bandiagara, Mali

scientific article published on 27 April 2015

Predicting Malaria Transmission Dynamics in Dangassa, Mali: A Novel Approach Using Functional Generalized Additive Models

scientific article published on 31 August 2020

Prevalence of malaria and factors associated with infection in children aged 6 months to 9 years in Guinea: Results from a national cross-sectional study

scientific article published on 02 July 2020

Quinine treatment selects the pfnhe-1 ms4760-1 polymorphism in Malian patients with Falciparum malaria

scientific article published on 16 November 2012

Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria

scientific article published in 2009

Reduced ex vivo susceptibility of Plasmodium falciparum after oral artemether-lumefantrine treatment in Mali

scientific article published on 02 February 2017

Relationship between weight status and anti-malarial drug efficacy and safety in children in Mali

scholarly article published by Issaka Sagara in 2019

Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact

scientific article

Risk factors for malaria infection and anemia for pregnant women in the Sahel area of Bandiagara, Mali

scientific article

Safety and allele-specific immunogenicity of a malaria vaccine in Malian adults: results of a phase I randomized trial

scientific article

Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

scientific article published on 21 October 2015

Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults

article

Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial

scientific article

Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial

scientific article

Season, fever prevalence and pyrogenic threshold for malaria disease definition in an endemic area of Mali

scientific article

Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali

scientific article

Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01E vaccine, seasonal malaria chemoprevention and the combination of vaccination and chemoprevention

scientific article published on 15 September 2020

Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine

scientific article

Short report: elevated levels of alanine aminotransferase and hepatitis A in the context of a pediatric malaria vaccine trial in a village in Mali.

scientific article published on December 2008

Sickle cell trait protects against Plasmodium falciparum infection

scientific article

Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village

scientific article

Spatio-Temporal Dynamic of Malaria Incidence: A Comparison of Two Ecological Zones in Mali

scientific article published on 30 June 2020

Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali

scientific article

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

scientific article published on 25 August 2009

The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence

scientific article

The duration of protection from azithromycin against malaria, acute respiratory, gastro-intestinal and skin infections when given alongside seasonal malaria chemoprevention: secondary analyses of data from a clinical trial in Houndé, Burkina Faso an

scientific article published on 08 January 2021

The etiology of severe anemia in a village and a periurban area in Mali

scientific article published on 27 April 2004

Two-Year Scale-Up of Seasonal Malaria Chemoprevention Reduced Malaria Morbidity among Children in the Health District of Koutiala, Mali

scientific article published on 11 September 2020

Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali

scientific article published on 03 September 2020

Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study

scientific article

Year-to-year variation in the age-specific incidence of clinical malaria in two potential vaccine testing sites in Mali with different levels of malaria transmission intensity.

scientific article published in December 2007

Zika Virus Circulation in Mali

scientific article published on 01 May 2020

Paulina is supported by:

About Paulina

Help