List of works - James Smiley

A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis ⬇️

scientific article published on October 1, 1978

Activation of RNA Polymerase III Transcription of Human Alu Repetitive Elements by Adenovirus Type 5: Requirement for the E1b 58-Kilodalton Protein and the Products of E4 Open Reading Frames 3 and 6 ⬇️

scientific article published on June 1, 1993

Activation of expression of multiple subfamilies of human Alu elements by adenovirus type 5 and herpes simplex virus type 1.

scientific article published on May 1995

Cell fusion-induced activation of interferon-stimulated genes is not required for restriction of a herpes simplex virus VP16/ICP0 mutant in heterokarya formed between permissive and restrictive cells.

scientific article

Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46.

scientific article published on 16 April 2008

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

scientific article published on July 1, 1977

Closely related reovirus lab strains induce opposite expression of RIG-I/IFN-dependent versus -independent host genes, via mechanisms of slow replication versus polymorphisms in dsRNA binding σ3 respectively

scientific article published on 21 September 2020

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus ⬇️

scientific article published on November 1, 1979

Construction in vitro and rescue of a thymidine kinase-deficient deletion mutation of herpes simplex virus.

scientific article published in May 1980

Construction of a double-jointed herpes simplex viral DNA molecule: inverted repeats are required for segment inversion, and direct repeats promote deletions

scientific article published on 01 August 1981

Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.

scientific article

Elimination of mitochondrial DNA is not required for herpes simplex virus 1 replication

scientific article

Evidence for translational regulation by the herpes simplex virus virion host shutoff protein

scientific article published on 31 March 2010

Expression of herpesvirus thymidine kinase gene under control of early promoter of SV40

scientific article published on 01 March 1982

Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein

scientific article published on 12 September 2018

Functional inaccessibility of quiescent herpes simplex virus genomes

scientific article

Genetic and physical evidence for the polarity of transcription of the thymidine kinase gene of herpes simplex virus ⬇️

scientific article published on April 15, 1980

Herpes Simplex Virus Requires VP11/12 To Activate Src Family Kinase-Phosphoinositide 3-Kinase-Akt Signaling ⬇️

scientific article published on January 12, 2011

Herpes simplex virus 1 infection of T cells causes VP11/12-dependent phosphorylation and degradation of the cellular protein Dok-2.

scientific article

Herpes simplex virus ICP0 mutants are hypersensitive to interferon

scientific article

Herpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells.

scientific article

Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene

scientific article

Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.

scientific article

Herpes simplex virus eliminates host mitochondrial DNA.

scientific article published on 22 December 2006

Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity ⬇️

scientific article

Herpes simplex virus vhs protein.

scientific article published in January 2001

Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H

scientific article

Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity.

scientific article

Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?

scientific article published on February 2004

Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag

scientific article

Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41

scientific article published on February 1, 1992

Mitochondrial DNA stress primes the antiviral innate immune response

scientific article

Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.

scientific article published on 28 August 2013

Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway.

scientific article published on 17 August 2016

Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc.

scientific article published on 14 August 2013

The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation.

scientific article published on 20 April 2016

The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.

scientific article published on 23 March 2011

The herpes simplex virus 1 virion host shutoff protein enhances translation of viral late mRNAs by preventing mRNA overload.

scientific article published on 11 June 2014

The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation

scientific article published on 20 August 2014

The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA

scientific article published on 18 October 2019

The vhs1 mutant form of herpes simplex virus virion host shutoff protein retains significant internal ribosome entry site-directed RNA cleavage activity.

scientific article published on January 2001

Transactivation of a Late Herpes Simplex Virus Promoter ⬇️

scientific article published on March 1, 1984

List of works by James Smiley

A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis ⬇️

Activation of RNA Polymerase III Transcription of Human Alu Repetitive Elements by Adenovirus Type 5: Requirement for the E1b 58-Kilodalton Protein and the Products of E4 Open Reading Frames 3 and 6 ⬇️

Activation of expression of multiple subfamilies of human Alu elements by adenovirus type 5 and herpes simplex virus type 1.

Cell fusion-induced activation of interferon-stimulated genes is not required for restriction of a herpes simplex virus VP16/ICP0 mutant in heterokarya formed between permissive and restrictive cells.

Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46.

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

Closely related reovirus lab strains induce opposite expression of RIG-I/IFN-dependent versus -independent host genes, via mechanisms of slow replication versus polymorphisms in dsRNA binding σ3 respectively

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus ⬇️

Construction in vitro and rescue of a thymidine kinase-deficient deletion mutation of herpes simplex virus.

Construction of a double-jointed herpes simplex viral DNA molecule: inverted repeats are required for segment inversion, and direct repeats promote deletions

Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.

Elimination of mitochondrial DNA is not required for herpes simplex virus 1 replication

Evidence for translational regulation by the herpes simplex virus virion host shutoff protein

Expression of herpesvirus thymidine kinase gene under control of early promoter of SV40

Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein

Functional inaccessibility of quiescent herpes simplex virus genomes

Genetic and physical evidence for the polarity of transcription of the thymidine kinase gene of herpes simplex virus ⬇️

Herpes Simplex Virus Requires VP11/12 To Activate Src Family Kinase-Phosphoinositide 3-Kinase-Akt Signaling ⬇️

Herpes simplex virus 1 infection of T cells causes VP11/12-dependent phosphorylation and degradation of the cellular protein Dok-2.

Herpes simplex virus ICP0 mutants are hypersensitive to interferon

Herpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells.

Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene

Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.

Herpes simplex virus eliminates host mitochondrial DNA.

Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity ⬇️

Herpes simplex virus vhs protein.

Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H

Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity.

Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?

Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag

Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41

Mitochondrial DNA stress primes the antiviral innate immune response

Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.

Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway.

Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc.

The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation.

The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.

The herpes simplex virus 1 virion host shutoff protein enhances translation of viral late mRNAs by preventing mRNA overload.

The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation

The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA

The vhs1 mutant form of herpes simplex virus virion host shutoff protein retains significant internal ribosome entry site-directed RNA cleavage activity.

Transactivation of a Late Herpes Simplex Virus Promoter ⬇️