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List of works by Chit-Laa Poh

A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence

scientific article published on 01 April 2019

Advances in Antigenic Peptide-Based Vaccine and Neutralizing Antibodies against Viruses Causing Hand, Foot, and Mouth Disease ⬇️

scientific article published on 13 March 2019

Antiviral Peptides against Enterovirus A71 causing Hand, Foot and Mouth Disease

scientific article published on 07 November 2020

Antiviral activity of silymarin and baicalein against dengue virus

scientific article published on 27 October 2021

Antiviral activity of silymarin in comparison with baicalein against EV-A71

scientific article published on 23 March 2020

Beta-actin variant is necessary for Enterovirus 71 replication.

scientific article published on 25 March 2013

Changes in the EV-A71 Genome through Recombination and Spontaneous Mutations: Impact on Virulence.

scientific article published on 12 June 2018

Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71

scientific article published on 17 June 2020

Characterization of hbzE-encoded gentisate 1,2-dioxygenase from Pseudomonas alcaligenes NCIMB 9867

scientific article published on 13 July 2007

Characterization of significant molecular determinants of virulence of Enterovirus 71 sub-genotype B4 in Rhabdomyosarcoma cells.

scientific article published on 10 July 2017

Cloning and characterization of a metalloprotease from Vibrio harveyi strain AP6.

scientific article

Cloning and characterization of a novel lipase from Vibrio harveyi strain AP6.

scientific article published on July 2003

Cloning and expression of the ApaLI, NspI, NspHI, SacI, ScaI, and SapI restriction-modification systems in Escherichia coli.

scientific article

Comparative proteome analyses of host protein expression in response to Enterovirus 71 and Coxsackievirus A16 infections

scientific article published on 19 May 2011

Complete sequence analyses of enterovirus 71 strains from fatal and non-fatal cases of the hand, foot and mouth disease outbreak in Singapore (2000).

scientific article published in January 2002

Construction of an infectious cDNA clone of Enterovirus 71: insights into the factors ensuring experimental success

scientific article published on 20 December 2013

Correction: Lalani, S. and Poh, C.L. Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71). Viruses 2020, 12, 184

scientific article published on 30 June 2020

Cross-reactive neutralizing antibody epitopes against Enterovirus 71 identified by an in silico approach.

scientific article published on 26 September 2012

Detection of Enteroviruses from Clinical Specimens ⬇️

scientific article published on January 1, 2011

Development of MicroRNAs as Potential Therapeutics against Cancer

scientific article published on 15 July 2020

Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection

scientific article published on 17 March 2020

Development of Novel Vaccines against Enterovirus-71

scientific article

Development of Novel miRNA-based Vaccines and Antivirals against Enterovirus 71.

scientific article published on 20 July 2016

Development of Peptide Vaccines in Dengue.

scientific article published on 13 September 2017

Development of RNA interference (RNAi) as potential antiviral strategy against enterovirus 70.

scientific article

Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins

scientific article published on 01 November 2019

Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice

article

Development of multiplex real-time hybridization probe reverse transcriptase polymerase chain reaction for specific detection and differentiation of Enterovirus 71 and Coxsackievirus A16.

scientific article

Development of potential antiviral strategy against coxsackievirus B4.

scientific article published on 7 March 2010

Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers.

scientific article

Direct identification of Pseudomonas aeruginosa from blood culture bottles by PCR-enzyme linked immunosorbent assay using oprI gene specific primers

scientific article

Distinct functional domains of PNMA5 mediate protein-protein interaction, nuclear localization, and apoptosis signaling in human cancer cells

scientific article

Enhanced potency and efficacy of 29-mer shRNAs in inhibition of Enterovirus 71.

scientific article published on 31 January 2007

Enhancement of Tetravalent Immune Responses to Highly Conserved Epitopes of a Dengue Peptide Vaccine Conjugated to Polystyrene Nanoparticles

scientific article published on 25 July 2020

Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor.

scientific article

Enterovirus-Specific Anti-peptide Antibodies

scientific article published on January 2015

Enzymatic profile of clinical isolates of Acinetobacter calcoaceticus

scientific article published in January 1985

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)

scientific article published on 06 February 2020

Genetic determinants of tetracycline resistance in Vibrio harveyi.

scientific article

Highly attenuated Bordetella pertussis strain BPZE1 as a potential live vehicle for delivery of heterologous vaccine candidates

scientific article

IS1491 from Pseudomonas alcaligenes NCIB 9867: characterization and distribution among Pseudomonas species.

scientific article published on January 1998

Identification of human CD4 T-cell epitopes on the VP1 capsid protein of enterovirus 71.

scientific article published in June 2008

Identification of immunodominant VP1 linear epitope of enterovirus 71 (EV71) using synthetic peptides for detecting human anti-EV71 IgG antibodies in Western blots.

scientific article published on 8 December 2007

Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71.

scientific article published on 28 November 2016

Identification of neutralizing linear epitopes from the VP1 capsid protein of Enterovirus 71 using synthetic peptides

scientific article published on 12 January 2007

Identification of vaccine candidate antigens of an ESBL producing Klebsiella pneumoniae clinical strain by immunoproteome analysis.

scientific article published in February 2006

Impact of RNA Virus Evolution on Quasispecies Formation and Virulence

scientific article published on 19 September 2019

Impact of genetic changes, pathogenicity and antigenicity on Enterovirus- A71 vaccine development

scientific article

In vitro evaluation of the antiviral activity of heparan sulfate mimetic compounds against Enterovirus 71.

scientific article published on 6 July 2012

Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1.

scientific article

Inhibition of enterovirus 71 in virus-infected mice by RNA interference.

scientific article

Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers

scientific article published on 24 April 2014

Inhibition of gene expression and growth by antisense peptide nucleic acids in a multiresistant beta-lactamase-producing Klebsiella pneumoniae strain

scientific article published on 11 December 2006

Insights into environmental bioremediation by microorganisms through functional genomics and proteomics.

scientific article published on February 2008

Insights into innate and adaptive immune responses in vaccine development against EV-A71

scientific article published on 21 November 2019

Isolation and characterization of group II introns from Pseudomonas alcaligenes and Pseudomonas putida.

scientific article published in May 2001

Molecular and biochemical characterization of the xlnD-encoded 3-hydroxybenzoate 6-hydroxylase involved in the degradation of 2,5-xylenol via the gentisate pathway in Pseudomonas alcaligenes NCIMB 9867

scientific article

Molecular characterization of an inducible gentisate 1,2-dioxygenase gene, xlnE, from Pseudomonas alcaligenes NCIMB 9867.

scientific article published on July 2003

Monitoring of active but non-culturable bacterial cells by flow cytometry.

scientific article published in January 2005

Neural Differentiation of Human Pluripotent Stem Cells for Nontherapeutic Applications: Toxicology, Pharmacology, and In Vitro Disease Modeling.

scientific article published on 25 May 2015

Novel beta-lactamase genes from two environmental isolates of Vibrio harveyi

scientific article

Novel multiplex oligonucleotide-conjugated bead suspension array for rapid identification of enterovirus 71 subgenogroups

scientific article

Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer.

scientific article published on 6 May 2019

PNMA family: Protein interaction network and cell signalling pathways implicated in cancer and apoptosis

scientific article published on 26 January 2018

Passive protection against lethal enterovirus 71 infection in newborn mice by neutralizing antibodies elicited by a synthetic peptide.

scientific article published on 10 June 2007

Peptides as Therapeutic Agents for Dengue Virus

scientific article published on 15 October 2017

Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy.

scientific article published on 6 January 2016

Polymerase chain reaction and direct sequencing of Neisseria gonorrhoeae protein IB gene: partial nucleotide and amino acid sequence analysis of strains S4, S11, S48 (serovar IB4) and S34 (serovar IB5).

scientific article published on July 1993

Protective efficacy of DNA vaccines encoding outer membrane protein A and OmpK36 of Klebsiella pneumoniae in mice.

scientific article

Proteome analysis of gentisate-induced response in Pseudomonas alcaligenes NCIB 9867.

scientific article

Proteome analysis of heat shock protein expression in Pseudomonas alcaligenes NCIMB 9867 in response to gentisate exposure and elevated growth temperature

scientific article published on 01 June 2007

Proteome investigation of the global regulatory role of sigma 54 in response to gentisate induction in Pseudomonas alcaligenes NCIMB 9867.

scientific article

Pulsed-field gel electrophoresis for differentiation of hospital isolates of Klebsiella pneumoniae

scientific article published on 01 June 1993

RNA interference against enterovirus 71 infection

scientific article

RT-PCR, nucleotide, amino acid and phylogenetic analyses of enterovirus type 71 strains from Asia.

scientific article published on August 2000

Rapid detection of Klebsiella pneumoniae from blood culture bottles by real-time PCR.

scientific article published on March 2004

Rapid detection of enterovirus 71 by real-time TaqMan RT-PCR.

scientific article published on 4 March 2008

Recent advances in delivery of veterinary DNA vaccines against avian pathogens

scientific article published on 10 October 2019

Replacement of tyrosine 181 by phenylalanine in gentisate 1,2-dioxygenase I from Pseudomonas alcaligenes NCIMB 9867 enhances catalytic activities.

scientific article

Role of microRNAs in antiviral responses to dengue infection

scientific article published on 03 January 2020

Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates from pediatric patients in Singapore

scientific article

Specific detection of enterovirus 71 directly from clinical specimens using real-time RT-PCR hybridization probe assay

scientific article published on 7 February 2006

Structural Vaccinology for Viral Vaccine Design

article by Mohd Ishtiaq Anasir & Chit Laa Poh published 2019 in Frontiers in Microbiology

Structure-Based Design of Antivirals against Envelope Glycoprotein of Dengue Virus

scientific article published on 26 March 2020

Synthetic B-Cell Epitopes Eliciting Cross-Neutralizing Antibodies: Strategies for Future Dengue Vaccine

scientific article

T Cell Immunity To Enterovirus 71 Infection In Humans And Implications For Vaccine Development

article

The Conserved Molecular Determinants of Virulence in Dengue Virus

The largest outbreak of hand; foot and mouth disease in Singapore in 2008: the role of enterovirus 71 and coxsackievirus A strains.

scientific article

Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1

scientific article published on 06 May 2020

Understanding the Differentiation, Expansion, Recruitment and Suppressive Activities of Myeloid-Derived Suppressor Cells in Cancers ⬇️

scientific article published on 20 May 2020

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