List of works - Oliver Ernst

7TM Domain Structure of Adhesion GPCRs

scientific article published on January 2016

A G protein-coupled receptor at work: the rhodopsin model.

scientific article published on 21 October 2009

A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin

scientific article published on 16 August 2018

A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals.

scientific article

A ligand channel through the G protein coupled receptor opsin

scientific article

A photo-cross-linking strategy to map sites of protein-protein interactions

scientific article published on 01 July 2010

Accessible virtual reality of biomolecular structural models using the Autodesk Molecule Viewer.

scientific article

Activation of the A2A adenosine G-protein-coupled receptor by conformational selection

scientific article published in Nature

Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells

scientific article

Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays.

scientific article published in May 1995

Characterizing rhodopsin signaling by EPR spectroscopy: from structure to dynamics

scientific article published on 03 July 2015

Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

scientific article published on 20 April 2011

Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints.

scientific article

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

scientific article published in Nature

Cryo-EM structure of the native rhodopsin dimer in nanodiscs

scientific article published on 09 August 2019

Crystal structure of metarhodopsin II

scientific article

Crystal structure of opsin in its G-protein-interacting conformation

scientific article

Crystal structure of pre-activated arrestin p44

scientific article

Crystal structure of the ligand-free G-protein-coupled receptor opsin

scientific article

Crystallization and preliminary X-ray studies of mouse centrin1

scientific article

Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.

scientific article

Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells

scientific journal article

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

scientific article published on 03 October 2016

Effect of channel mutations on the uptake and release of the retinal ligand in opsin.

scientific article published on 19 March 2012

Engineering of an artificial light-modulated potassium channel.

scientific article

Erratum to: 7TM Domain Structure of Adhesion GPCRs.

scientific article

Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography

scientific article

Fixed target matrix for femtosecond time-resolved and in situ serial micro-crystallography

scientific article published on 18 August 2015

Fixed-target serial oscillation crystallography at room temperature

scientific article published on 23 February 2019

G protein-coupled receptor modulation with pepducins: moving closer to the clinic

scientific article published on 01 May 2011

Gi- and Gs-coupled GPCRs show different modes of G-protein binding

scientific article published on 20 February 2018

High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

scientific article published on 4 January 2018

Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.

scientific article published on July 2017

Incorporation of rhodopsin in laterally structured supported membranes: observation of transducin activation with spatially and time-resolved surface plasmon resonance.

scientific article published on January 1998

Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1.

scientific article published on 6 October 2006

Intrinsic biophysical monitors of transducin activation: fluorescence, UV-visible spectroscopy, light scattering, and evanescent field techniques.

scientific article published in January 2000

Ion channel in the spotlight

journal article; published in Nature on 2012-02-15

Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum

scientific article published on 25 August 2017

Local vibrational coherences drive the primary photochemistry of vision

scientific article

Low-dose fixed-target serial synchrotron crystallography.

scientific article

Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations.

scientific article

Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.

scientific article published on 23 December 2013

Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation.

scientific article published in November 1999

Molecular assembly of rhodopsin with G protein-coupled receptor kinases.

scientific article

Molecular motions and hydration of purple membranes and disk membranes studied by neutron scattering.

scientific article published in January 1998

Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding

scientific article

Opsin, a structural model for olfactory receptors?

scientific article

Phospholipid scrambling by rhodopsin.

scientific article published on 16 July 2015

Proton transfer reactions linked to rhodopsin activation.

scientific article published in October 1998

Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

scientific article published in Nature

Recent advances in biophysical studies of rhodopsins - Oligomerization, folding, and structure.

scientific article published on 24 August 2017

Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis.

scientific article published on 29 September 2006

Sequence of interactions in receptor-G protein coupling.

scientific article published on 8 March 2004

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

scientific article published on 17 July 2006

Stationary Phase EPR Spectroscopy for Monitoring Membrane Protein Refolding by Conformational Response

scientific article published on 11 December 2018

Structure of the glucagon receptor in complex with a glucagon analogue

scientific article published in January 2018

Synthesis and spectroscopic characterization of photo-affinity peptide ligands to study rhodopsin-G protein interaction

scientific article published on 14 February 2008

Synthesis of Chiral Spin-Labeled Amino Acids

scientific article published on 10 December 2019

TakeTwo: an indexing algorithm suited to still images with known crystal parameters

scientific article

The Primary Photochemistry of Vision Occurs at the Molecular Speed Limit

scientific article published on 30 March 2017

The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants

scientific article published on 23 July 2020

The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system.

scientific article published on 16 September 2015

The photocycle and ultrafast vibrational dynamics of bacteriorhodopsin in lipid nanodiscs

article

To see from light--biophysics of visual signal transduction

scientific article published in January 2001

Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.

scientific article

Transmembrane signaling by GPCRs: insight from rhodopsin and opsin structures.

scientific article published on 12 August 2010

Utilizing tagged paramagnetic shift reagents to monitor protein dynamics by NMR.

scientific article published on 22 September 2017

X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin

scientific article published on 02 August 2019

X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization

scientific article

List of works by Oliver Ernst

7TM Domain Structure of Adhesion GPCRs

A G protein-coupled receptor at work: the rhodopsin model.

A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin

A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals.

A ligand channel through the G protein coupled receptor opsin

A photo-cross-linking strategy to map sites of protein-protein interactions

Accessible virtual reality of biomolecular structural models using the Autodesk Molecule Viewer.

Activation of the A2A adenosine G-protein-coupled receptor by conformational selection

Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells

Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays.

Characterizing rhodopsin signaling by EPR spectroscopy: from structure to dynamics

Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints.

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

Cryo-EM structure of the native rhodopsin dimer in nanodiscs

Crystal structure of metarhodopsin II

Crystal structure of opsin in its G-protein-interacting conformation

Crystal structure of pre-activated arrestin p44

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Crystallization and preliminary X-ray studies of mouse centrin1

Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.

Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

Effect of channel mutations on the uptake and release of the retinal ligand in opsin.

Engineering of an artificial light-modulated potassium channel.

Erratum to: 7TM Domain Structure of Adhesion GPCRs.

Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography

Fixed target matrix for femtosecond time-resolved and in situ serial micro-crystallography

Fixed-target serial oscillation crystallography at room temperature

G protein-coupled receptor modulation with pepducins: moving closer to the clinic

Gi- and Gs-coupled GPCRs show different modes of G-protein binding

High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.

Incorporation of rhodopsin in laterally structured supported membranes: observation of transducin activation with spatially and time-resolved surface plasmon resonance.

Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1.

Intrinsic biophysical monitors of transducin activation: fluorescence, UV-visible spectroscopy, light scattering, and evanescent field techniques.

Ion channel in the spotlight

Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum

Local vibrational coherences drive the primary photochemistry of vision

Low-dose fixed-target serial synchrotron crystallography.

Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations.

Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.

Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation.

Molecular assembly of rhodopsin with G protein-coupled receptor kinases.

Molecular motions and hydration of purple membranes and disk membranes studied by neutron scattering.

Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding

Opsin, a structural model for olfactory receptors?

Phospholipid scrambling by rhodopsin.

Proton transfer reactions linked to rhodopsin activation.

Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

Recent advances in biophysical studies of rhodopsins - Oligomerization, folding, and structure.

Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis.

Sequence of interactions in receptor-G protein coupling.

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

Stationary Phase EPR Spectroscopy for Monitoring Membrane Protein Refolding by Conformational Response

Structure of the glucagon receptor in complex with a glucagon analogue

Synthesis and spectroscopic characterization of photo-affinity peptide ligands to study rhodopsin-G protein interaction

Synthesis of Chiral Spin-Labeled Amino Acids

TakeTwo: an indexing algorithm suited to still images with known crystal parameters

The Primary Photochemistry of Vision Occurs at the Molecular Speed Limit

The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants

The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system.

The photocycle and ultrafast vibrational dynamics of bacteriorhodopsin in lipid nanodiscs

To see from light--biophysics of visual signal transduction

Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.

Transmembrane signaling by GPCRs: insight from rhodopsin and opsin structures.

Utilizing tagged paramagnetic shift reagents to monitor protein dynamics by NMR.

X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin

X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization