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List of works by Michael R. Kanost

A genome-wide analysis of antimicrobial effector genes and their transcription patterns in Manduca sexta.

scientific article published on 3 February 2015

A multicopper oxidase-related protein is essential for insect viability, longevity and ovary development

scientific article

A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases.

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Abstracts of the Fifth International Symposium on Molecular Insect Science: May 20–24, 2006, Tucson, Arizona USA, Organizing Committee.

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An Initial Event in the Insect Innate Immune Response: Structural and Biological Studies of Interactions between β-1,3-Glucan and the N-Terminal Domain of β-1,3-Glucan Recognition Protein

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An insight into the transcriptome and proteome of the salivary gland of the stable fly, Stomoxys calcitrans

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Analysis of chitin-binding proteins from Manduca sexta provides new insights into evolution of peritrophin A-type chitin-binding domains in insects.

scientific article published on 15 December 2014

Annotation and expression analysis of cuticular proteins from the tobacco hornworm, Manduca sexta

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Bacterial challenge stimulates innate immune responses in extra-embryonic tissues of tobacco hornworm eggs.

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Binding of hemolin to bacterial lipopolysaccharide and lipoteichoic acid. An immunoglobulin superfamily member from insects as a pattern-recognition receptor.

scientific article published on April 2002

Biological Insights from the Manduca sexta genome. Preface.

scientific article published on 20 May 2015

Biological activity of Manduca sexta paralytic and plasmatocyte spreading peptide and primary structure of its hemolymph precursor.

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Characterization and regulation of expression of an antifungal peptide from hemolymph of an insect, Manduca sexta.

scientific article published on 11 March 2016

Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes.

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Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development.

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Characterization of tyrosine hydroxylase from Manduca sexta.

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Chitin synthase genes in Manduca sexta: characterization of a gut-specific transcript and differential tissue expression of alternately spliced mRNAs during development.

scientific article published on 7 March 2005

Clustering of adhesion receptors following exposure of insect blood cells to foreign surfaces.

scientific article published on May 2005

Comparative analysis of serine protease-related genes in the honey bee genome: possible involvement in embryonic development and innate immunity

scientific article published on October 2006

Comparative analysis of seven types of superoxide dismutases for their ability to respond to oxidative stress in Bombyx mori

scientific article published on 18 February 2019

Cuticular protein with a low complexity sequence becomes cross-linked during insect cuticle sclerotization and is required for the adult molt.

scientific article published on 21 May 2015

Development of a new method for collecting hemolymph and measuring phenoloxidase activity in Tribolium castaneum

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Effects of parasitism by the braconid wasp Cotesia congregata on host hemolymph proteins of the tobacco hornworm, Manduca sexta.

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Expression and purification of Manduca sexta prophenoloxidase-activating proteinase precursor (proPAP) from baculovirus-infected insect cells.

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Formation of rigid, non-flight forewings (elytra) of a beetle requires two major cuticular proteins.

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Four serine proteinases expressed in Manduca sexta haemocytes.

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Hematopoietic organs of Manduca sexta and hemocyte lineages

scientific article published on August 28, 2003

Hemolymph proteinases in immune responses of Manduca sexta.

scientific article published on January 2001

Identification by subtractive suppression hybridization of bacteria-induced genes expressed in Manduca sexta fat body.

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Identification of plasma proteinase complexes with serpin-3 in Manduca sexta.

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Immulectin-2, a lipopolysaccharide-specific lectin from an insect, Manduca sexta, is induced in response to gram-negative bacteria.

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Immulectin-2, a pattern recognition receptor that stimulates hemocyte encapsulation and melanization in the tobacco hornworm, Manduca sexta.

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Immune pathways and defence mechanisms in honey bees Apis mellifera.

scientific article published on October 2006

Immunity in lepidopteran insects.

scientific article published on January 2010

Immunochemical identification of insect hemocyte populations: monoclonal antibodies distinguish four major hemocyte types in manduca sexta.

scientific article published on December 1994

Initiating protease with modular domains interacts with β-glucan recognition protein to trigger innate immune response in insects.

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Innate immunity in a pyralid moth: functional evaluation of domains from a beta-1,3-glucan recognition protein.

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Kinetic properties of alternatively spliced isoforms of laccase-2 from Tribolium castaneum and Anopheles gambiae.

scientific article published on 16 December 2011

Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning

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Leureptin: a soluble, extracellular leucine-rich repeat protein from Manduca sexta that binds lipopolysaccharide.

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Loss of function of the yellow-e gene causes dehydration-induced mortality of adult Tribolium castaneum

scientific article published on 19 January 2015

Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph

scientific article published on 23 May 2018

Manduca sexta serpin-4 and serpin-5 inhibit the prophenol oxidase activation pathway: cDNA cloning, protein expression, and characterization.

scientific article published on 28 January 2005

Mechanical properties of elytra from Tribolium castaneum wild-type and body color mutant strains.

scientific article published on 26 August 2010

Mechanical properties of the beetle elytron, a biological composite material.

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Model reactions for insect cuticle sclerotization: cross-linking of recombinant cuticular proteins upon their laccase-catalyzed oxidative conjugation with catechols.

scientific article published on 19 January 2006

Model reactions for insect cuticle sclerotization: participation of amino groups in the cross-linking of Manduca sexta cuticle protein MsCP36.

scientific article published on 26 February 2010

Modulation of bovine lymphocyte response by salivary gland extracts of the stable fly, Stomoxys calcitrans (Diptera: Muscidae).

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Molecular and functional analyses of amino acid decarboxylases involved in cuticle tanning in Tribolium castaneum.

scientific article published on 14 April 2009

Molecular cloning of a multidomain cysteine protease and protease inhibitor precursor gene from the tobacco hornworm (Manduca sexta) and functional expression of the cathepsin F-like cysteine protease domain

scientific article published on August 18, 2010

Molecular identification of a bevy of serine proteinases in Manduca sexta hemolymph.

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Multicopper Oxidase-3 Is a Laccase Associated with the Peritrophic Matrix of Anopheles gambiae

scientific article published on March 27, 2012

Multicopper oxidase-1 is a ferroxidase essential for iron homeostasis in Drosophila melanogaster.

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Multicopper oxidase-1 orthologs from diverse insect species have ascorbate oxidase activity.

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Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta.

scientific article published on 11 August 2016

Neuroglian on hemocyte surfaces is involved in homophilic and heterophilic interactions of the innate immune system of Manduca sexta.

scientific article published on 2 April 2007

Overview of chitin metabolism enzymes in Manduca sexta: Identification, domain organization, phylogenetic analysis and gene expression.

scientific article published on 20 January 2015

Pattern recognition proteins in Manduca sexta plasma.

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Pectinmethylesterase from the rice weevil, Sitophilus oryzae: cDNA isolation and sequencing, genetic origin, and expression of the recombinant enzyme

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Phylogenetic analysis and expression profiling of the pattern recognition receptors: Insights into molecular recognition of invading pathogens in Manduca sexta

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Pro-phenol oxidase activating proteinase from an insect, Manduca sexta: a bacteria-inducible protein similar to Drosophila easter.

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Protease inhibitors of Manduca sexta expressed in transgenic cotton

scientific article published in October 1995

Proteomic and transcriptomic analyses of rigid and membranous cuticles and epidermis from the elytra and hindwings of the red flour beetle, Tribolium castaneum.

scientific article published on 30 November 2011

Purification of a cysteine protease inhibitor from larval hemolymph of the tobacco hornworm (Manduca sexta) and functional expression of the recombinant protein.

scientific article published on 18 May 2007

RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.

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RNAi-induced silencing of embryonic tryptophan oxygenase in the Pyralid moth, Plodia interpunctella

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Redox potentials, laccase oxidation, and antilarval activities of substituted phenols

scientific article published on January 21, 2012

Self-assembled coacervates of chitosan and an insect cuticle protein containing a Rebers-Riddiford motif.

scientific article published on 26 April 2018

Self-association of an insect β-1,3-glucan recognition protein upon binding laminarin stimulates prophenoloxidase activation as an innate immune response

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Sequence conservation, phylogenetic relationships, and expression profiles of nondigestive serine proteases and serine protease homologs in Manduca sexta

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Serine proteinase inhibitors in arthropod immunity.

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Serpin-1 splicing isoform J inhibits the proSpätzle-activating proteinase HP8 to regulate expression of antimicrobial hemolymph proteins in Manduca sexta

scientific article published on September 22, 2010

Serpins from an insect, Manduca sexta.

scientific article published on January 1997

Serpins in arthropod biology.

scientific article published on 4 September 2016

Structural and inhibitory effects of hinge loop mutagenesis in serpin-2 from the malaria vector Anopheles gambiae

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Structural features, evolutionary relationships, and transcriptional regulation of C-type lectin-domain proteins in Manduca sexta

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Structure of a paralytic peptide from an insect, Manduca sexta

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Subunit composition of pro-phenol oxidase from Manduca sexta: molecular cloning of subunit ProPO-P1.

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Superoxide dismutase 2 knockdown leads to defects in locomotor activity, sensitivity to paraquat, and increased cuticle pigmentation in Tribolium castaneum.

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The Manduca sexta serpinome: Analysis of serpin genes and proteins in the tobacco hornworm

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The extracellular matrix protein lacunin is expressed by a subset of hemocytes involved in basal lamina morphogenesis.

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The immune properties of Manduca sexta transferrin.

scientific article published on 13 December 2016

The serpin gene family in Anopheles gambiae.

scientific article published on 24 April 2009

The structure of a Michaelis serpin-protease complex

scientific article published on November 1, 2001

Tribolium castaneum as a Model for High-Throughput RNAi Screening

scientific article published on January 1, 2013

Two major cuticular proteins are required for assembly of horizontal laminae and vertical pore canals in rigid cuticle of Tribolium castaneum.

scientific article published on 18 July 2014