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List of works by Aideen Long

A fluorescent analogue of tauroursodeoxycholic acid reduces ER stress and is cytoprotective

scientific article published on 23 June 2016

A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization.

scientific article

Advances in bile acid medicinal chemistry.

scientific article published on January 2011

Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection

scientific article published on October 2013

An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.

scientific article

Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.

scientific article

Aromatic aldehydes as substrates for yeast and yeast alcohol dehydrogenase

scientific article published on 01 January 1989

Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).

scientific article published on 19 July 2010

Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.

scientific article published on 21 January 2010

Biotransformation of benzaldehyde by Saccharomyces cerevisiae: characterization of the fermentation and toxicity effects of substrates and products.

scientific article published in October 1989

CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes.

scientific article

Candidate Gene Knockdown in Celiac Disease

article

Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78.

scientific article published on March 1995

Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-1α and MIP-1β with consequent directed migration of activated lymphocytes

scientific article published in October 2000

Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells.

scientific article published in June 2001

Deoxycholic acid impairs glycosylation and fucosylation processes in esophageal epithelial cells.

scientific article published on 4 January 2012

Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line

scientific article published on April 27, 1992

Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells.

scientific article published on 7 January 2005

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion.

scientific article published on 13 October 2015

Hepatitis C virus--T-cell responses and viral escape mutations.

scientific article

L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes

scientific article published on 11 May 2012

Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

scientific article published on 3 August 2007

Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?

scientific article published on 01 October 2005

New fluorescent bile acids: synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid

scientific article published on 12 January 2012

New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.

scientific article

Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration.

scientific article

Protein kinase C and T cell function ⬇️

scientific article published on September 11, 1997

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease ⬇️

scientific article published on January 26, 2013

Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.

scientific article

RACK1 to the future--a historical perspective

scientific article

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration.

scientific article published on 29 May 2015

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites.

scientific article published on 12 October 2010

Regulation of non-classical protein kinase C isoenzymes in a human T cell line.

scientific article published on January 1995

Roles for RACK1 in cancer cell migration and invasion

scientific article published on 21 March 2017

STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL.

scientific article published on 5 March 2010

Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway.

scientific article

Statistical methods for analysis of high-throughput RNA interference screens

scientific article

Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes.

scientific article published in August 2005

Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes

scientific article published in October 1997

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11 ⬇️

scientific article published on October 8, 2010

TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes.

scientific article published on February 1997

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility ⬇️

scientific article published on March 29, 2011

The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers.

scientific article published on June 2005

The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells.

scientific article published on April 2006

The role of chemokines in acute and chronic hepatitis C infection ⬇️

scientific article published on August 19, 2013

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism.

scientific article published on 23 November 2016

Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators.

scientific article published on 15 December 2010

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