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List of works by Takashi Funatsu

A spontaneously blinking fluorophore based on intramolecular spirocyclization for live-cell super-resolution imaging.

scientific article

ASK1 signalling regulates brown and beige adipocyte function.

scientific article published on 5 April 2016

Amino acid analysis using core-shell particle column

scientific article published on 07 September 2012

Amino acids analysis using a monolithic silica column after derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F)

scientific article published on 29 December 2010

Analytical methods involving separation techniques for determination of low-molecular-weight biothiols in human plasma and blood

scientific article published on 21 January 2014

Catecholamine analysis with microcolumn LC-peroxyoxalate chemiluminescence reaction detection.

scientific article published on 2 November 2005

Catecholamine analysis with strong cation exchange column liquid chromatography-peroxyoxalate chemiluminescence reaction detection

scientific article published on 11 November 2011

Cellular responses of the ciliate, Tetrahymena thermophila, to far infrared irradiation.

scientific article published on 4 August 2006

Changes in mobility of chromaffin granules in actin network with its assembly and Ca(2+)-dependent disassembly by gelsolin.

scientific article published on April 1993

Characterization of beta-actinin: a suppressor of the elongation at the pointed end of thin filaments in skeletal muscle

scientific article published in 1985

Collection of biochemical samples with brain-wide electrophysiological recordings from a freely moving rodent

scientific article published on 27 February 2019

Construction of integrated gene logic-chip

scientific article published on 23 July 2018

Culture-independent method for identification of microbial enzyme-encoding genes by activity-based single-cell sequencing using a water-in-oil microdroplet platform.

scientific article published on 26 February 2016

DNA micropatterning on polycrystalline diamond via one-step direct amination.

scientific article

Denatured proteins facilitate the formation of the football-shaped GroEL-(GroES)2 complex.

scientific article published on 29 March 2010

Detection and Quantification of MicroRNAs by Ligase-Assisted Sandwich Hybridization on a Microarray

scientific article published on 01 January 2016

Determination and characterization of total thiols in mouse serum samples using hydrophilic interaction liquid chromatography with fluorescence detection and mass spectrometry.

scientific article published on 2 December 2015

Determination of NG,NG-dimethyl-L-arginine in rat plasma and dimethylarginine dimethylaminohydrolase activity in rat kidney using a monolithic silica column

scientific article published on 23 June 2006

Determination of catecholamines and related compounds in mouse urine using column-switching HPLC

scientific article published on 31 March 2016

Determination of methylated arginines by column-switching high-performance liquid chromatography-fluorescence detection.

scientific article published on 15 August 2005

Determination of potent antisense oligonucleotides in vitro by semiempirical rules.

scientific article published on March 2007

Determination of selenomethionine by high-performance liquid chromatography-fluorescence detection coupled with on-line oxidation.

scientific article published in January 2009

Development of analytical method for catechol compounds in mouse urine using hydrophilic interaction liquid chromatography with fluorescence detection

scientific article published on 03 February 2015

Dynamic association-dissociation and harboring of endogenous mRNAs in stress granules

scientific article published on 01 December 2011

ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue

scientific article published on 06 February 2020

Effect of Nanoparticle Surface on the HPLC Elution Profile of Liposomal Nanoparticles.

scientific article

Extraction of cell-free DNA from urine, using polylysine-coated silica particles.

scientific article published on 19 April 2017

Facilitated release of substrate protein from prefoldin by chaperonin.

scientific article published in July 2005

Fast and quantitative analysis of branched-chain amino acids in biological samples using a pillar array column

scientific article published on May 25, 2013

Fast and simultaneous analysis of biothiols by high-performance liquid chromatography with fluorescence detection under hydrophilic interaction chromatography conditions.

scientific article

Fluorescence labeling of a cytokine with desthiobiotin-tagged fluorescent puromycin.

scientific article

Football- and bullet-shaped GroEL-GroES complexes coexist during the reaction cycle.

scientific article published on 20 June 2008

GroEL mediates protein folding with a two successive timer mechanism.

scientific article

High performance liquid chromatography analysis of 100-nm liposomal nanoparticles using polymer-coated, silica monolithic columns with aqueous mobile phase.

scientific article published on 29 December 2016

High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent.

scientific article published in February 2005

Hydrophilic fluorescent nanogel thermometer for intracellular thermometry.

scientific article

Hyperactivity in novel environment with increased dopamine and impaired novelty preference in apoptosis signal-regulating kinase 1 (ASK1)-deficient mice.

scientific article published on 16 December 2009

Identification of methylated tubulin through analysis of methylated lysine

scientific article published on 07 May 2018

Imaging and nano-manipulation of single biomolecules

scientific article published on 01 October 1997

Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution

scientific article published in Nature

Imaging of single fluorescent molecules using video-rate confocal microscopy.

scientific article

Improving zero-mode waveguide structure for enhancing signal-to-noise ratio of real-time single-molecule fluorescence imaging: a computational study

scientific article published on 30 July 2013

Infrared laser-mediated gene induction in targeted single cells in vivo.

scientific article

Initiation factor 2, tRNA, and 50S subunits cooperatively stabilize mRNAs on the ribosome during initiation.

scientific article published on 12 March 2012

Integration in a multilayer microfluidic chip of 8 parallel cell sorters with flow control by sol-gel transition of thermoreversible gelation polymer.

scientific article

Integration of pillar array columns into a gradient elution system for pressure-driven liquid chromatography.

scientific article published on 18 May 2012

Interhead distances in myosin attached to F-actin estimated by fluorescence energy transfer spectroscopy

scientific article published on August 1, 1997

Intracellular temperature mapping with a fluorescent polymeric thermometer and fluorescence lifetime imaging microscopy

scientific article published on 28 February 2012

Ischemic Brain Injury Leads to Brain Edema via Hyperthermia-Induced TRPV4 Activation

scientific article published on 23 May 2018

Kinetic analysis of conformational changes of GroEL based on the fluorescence of tyrosine 506.

scientific article

Kinetic study of de novo chromophore maturation of fluorescent proteins

scientific article published on July 15, 2011

Kinetics and binding sites for interaction of the prefoldin with a group II chaperonin: contiguous non-native substrate and chaperonin binding sites in the archaeal prefoldin.

scientific article

Label-free DNA sensors using ultrasensitive diamond field-effect transistors in solution.

scientific article published on 27 October 2006

Label-free quantification of microRNAs using ligase-assisted sandwich hybridization on a DNA microarray

scientific article

Liquid Chromatography Chip with Low-Dispersion and Low-Pressure-Drop Turn Structure Utilizing a Distribution-Controlled Pillar Array

scientific article published on 8 June 2016

Live-cell single-molecule imaging of the cytokine receptor MPL for analysis of dynamic dimerization.

scientific article published on 9 June 2016

Localization of prefoldin interaction sites in the hyperthermophilic group II chaperonin and correlations between binding rate and protein transfer rate.

scientific article published on 5 September 2006

Measurement of catechol-O-methyltransferase activity in the brain of Dahl salt-sensitive rats.

scientific article published in November 2007

Microscopic analysis of polymerization dynamics with individual actin filaments

scientific article published on 01 September 2002

NanoPARCEL: a method for controlling cellular behavior with external light

scientific article published on 16 July 2012

Nascent SecM chain outside the ribosome reinforces translation arrest

scientific article published on 25 March 2015

Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription.

scientific article published in March 2006

On-chip cell sorting system using laser-induced heating of a thermoreversible gelation polymer to control flow.

scientific article published in February 2006

On-chip microfluidic sorting with fluorescence spectrum detection and multiway separation.

scientific article published on 13 February 2009

Optimization of tris(2-carboxyethyl) phosphine reduction conditions for fast analysis of total biothiols in mouse serum samples

scientific article published on 11 May 2019

Oxidative stress increases 6-nitronorepinephrine and 6-nitroepinephrine concentrations in rat brain.

scientific article

Patterning of DNA nanostructures on silicon surface by electron beam lithography of self-assembled monolayer.

scientific article published on 5 March 2004

Rapid and sensitive detection method of a bacterium by using a GFP reporter phage.

scientific article published in January 2002

Rapid assay for catechol-O-methyltransferase activity by high-performance liquid chromatography-fluorescence detection.

scientific article published in May 2005

Rapid determination of amino acids in biological samples using a monolithic silica column

scientific article published on 20 April 2011

Rapid quantitative method for the detection of phenylalanine and tyrosine in human plasma using pillar array columns and gradient elution.

scientific article published on 21 May 2016

Real time monitoring of endogenous cytoplasmic mRNA using linear antisense 2'-O-methyl RNA probes in living cells

scientific article published on 23 November 2010

Real-Time Single-Molecule Observation of Green Fluorescent Protein Synthesis by Immobilized Ribosomes

scientific article published on January 1, 2011

Real-time imaging of single-molecule fluorescence with a zero-mode waveguide for the analysis of protein-protein interaction.

scientific article

Recent advances in hydrophilic interaction chromatography for quantitative analysis of endogenous and pharmaceutical compounds in plasma samples.

scientific article

Retention of Fluorescent Amino Acid Derivatives in Ion-pairing Reversed-phase Liquid Chromatography

scientific article published on 01 January 2018

Simultaneous determination of dopamine and 3,4-dihydroxyphenylacetic acid in mouse striatum using mixed-mode reversed-phase and cation-exchange high-performance liquid chromatography.

scientific article published on 2 October 2009

Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin.

scientific article published in January 1998

Single molecule tracking of quantum dot-labeled mRNAs in a cell nucleus.

scientific article published on 8 February 2009

Single-Molecule Tracking of mRNA in Living Cells

scientific article published on January 1, 2013

Single-molecule Observation of Protein Folding in Symmetric GroEL-(GroES)2 Complexes

scientific article published on October 9, 2012

Single-molecule analysis of the actomyosin motor using nano-manipulation

scientific article published on 01 March 1994

Single-molecule fluorescence polarization study of conformational change in archaeal group II chaperonin.

scientific article

Single-molecule imaging of beta-actin mRNAs in the cytoplasm of a living cell.

scientific article published on 23 February 2009

Single-molecule study on the decay process of the football-shaped GroEL-GroES complex using zero-mode waveguides.

scientific article published on 28 May 2010

Size distribution of linear and helical polymers in actin solution analyzed by photon counting histogram.

scientific article

Structural and functional reconstitution of thin filaments in skeletal muscle

scientific article published on 01 April 1994

Suppression of catechol-O-methyltransferase activity through blunting of alpha2-adrenoceptor can explain hypertension in Dahl salt-sensitive rats

scientific article published on 01 March 2007

Suppression of thiol exchange reaction in the determination of reduced-form thiols by high-performance liquid chromatography with fluorescence detection after derivatization with fluorogenic benzofurazan reagent, 7-fluoro-2,1,3-benzoxadiazole-4-sulf

scientific article published in June 2006

Synthesis of benzofurazan derivatization reagents for carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry.

scientific article

Synthesis of the isotope-labeled derivatization reagent for carboxylic acids, 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperazino-2,1,3-benzoxadiazole (d6) [DBD-PZ-NH2 (D)], and its application to the quantification and the determination of [...]

scientific article published in April 2006

Transition of β-Actinin Isoforms during Development of Chicken Skeletal Muscle1

scientific article published on January 1, 1988

Use of folded micromachined pillar array column with low-dispersion turns for pressure-driven liquid chromatography.

scientific article published in February 2010

Visualization of the molecular dynamics of lipopolysaccharide on the plasma membrane of murine macrophages by total internal reflection fluorescence microscopy.

scientific article

[Single-molecule imaging and quantification of mRNAs in a living cell]

scientific article published on 01 March 2009

cDNA display: a novel screening method for functional disulfide-rich peptides by solid-phase synthesis and stabilization of mRNA-protein fusions.

scientific article published on 15 June 2009

p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.

scientific article published in September 2011

β-Actinin Isoforms in Various Types of Muscle and Non-Muscle Tissues1

scientific article published on January 1, 1988

β-Actinin: A Capping Protein at the Pointed End of Thin Filaments in Skeletal Muscle1

scientific article published on 01 January 1988