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List of works by William G. Gutheil

A Dde resin based strategy for inverse solid-phase synthesis of amino terminated peptides, peptide mimetics and protected peptide intermediates

scientific article published on 01 February 2005

A Sensitive Equilibrium-Based Assay ford-Lactate Usingd-Lactate Dehydrogenase: Application to Penicillin-Binding Protein/dd-Carboxypeptidase Activity Assays ⬇️

scientific article published on May 15, 1998

A liquid chromatography-tandem mass spectrometry assay for detection and quantitation of the dipeptide Gly-Gln in rat brain.

scientific article published on 21 March 2012

A microtiter plate-based beta-lactam binding assay for inhibitors of high-molecular-mass penicillin-binding proteins.

scientific article published on 11 September 2009

A simple chemical example of hierarchical thermodynamic interactions: the protonation equilibria of inorganic polyprotic acids

scientific article published on 01 December 2000

Antibiotic Effects on Methicillin-Resistant Staphylococcus aureus Cytoplasmic Peptidoglycan Intermediate Levels and Evidence for Potential Metabolite Level Regulatory Loops.

scientific article

Application of hierarchical thermodynamic interactions to the protonation equilibria of organic polyprotic acids

scientific article published on 01 December 2000

Characterization of d-boroAla as a novel broad-spectrum antibacterial agent targeting d-Ala-d-Ala ligase.

scientific article

Convenient expression, purification and quantitative liquid chromatography-tandem mass spectrometry-based analysis of TET2 5-methylcytosine demethylase.

scientific article published on 8 February 2017

Crocetin: an Agent Derived from Saffron for Prevention and Therapy for Cancer ⬇️

scientific article published on January 1, 2012

Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells.

scientific article

Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation.

scientific article published in June 2005

Cytoplasmic peptidoglycan intermediate levels in Staphylococcus aureus.

scientific article

Derivation and numerical profile analysis of a hierarchically formulated microscopic model of hemoglobin oxygen binding

scientific article published on 04 August 2018

Dimensionally Enhanced Antibacterial Library Screening

scientific article published on 13 November 2019

Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase

article

Fluorescent coupled enzyme assays for D-alanine: application to penicillin-binding protein and vancomycin activity assays

scientific article published on 01 December 2000

Gaussian and linear deconvolution of LC-MS/MS chromatograms of the eight aminobutyric acid isomers.

scientific article published on 19 October 2016

Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.

scientific article published on July 1994

Identification of non-histone substrates for JMJD2A-C histone demethylases.

scientific article published on 30 September 2009

Induction of glutathione-dependent formaldehyde dehydrogenase activity in Escherichia coli and Hemophilus influenza

scientific article published on 01 September 1997

Ion-pairing liquid chromatography-tandem mass spectrometry-based quantification of uridine diphosphate-linked intermediates in the Staphylococcus aureus cell wall biosynthesis pathway.

scientific article published on 30 July 2014

Jatropha curcas: from biodiesel generation to medicinal applications.

scientific article published on December 2012

Kinlsq: a program for fitting kinetics data with numerically integrated rate equations and its application to the analysis of slow, tight-binding inhibition data.

scientific article published on November 1994

LC-MS/MS-Based Separation and Quantification of Marfey's Reagent Derivatized Proteinogenic Amino Acid DL-Stereoisomers

scientific article published on 12 November 2018

Microtiter plate-based assay for inhibitors of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus.

scientific article

Multivariate geometrical analysis of catalytic residues in the penicillin-binding proteins.

scientific article published on 29 June 2011

Neisseria gonorrhoeae penicillin-binding protein 3 demonstrates a pronounced preference for N(epsilon)-acylated substrates.

scientific article published on June 2009

Neisseria gonorrhoeae penicillin-binding protein 3 exhibits exceptionally high carboxypeptidase and beta-lactam binding activities.

scientific article published in December 2003

Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4.

scientific article published in January 2004

Potential transition state analogue inhibitors for the penicillin-binding proteins.

scientific article published in January 2003

Purification, characterization, and partial sequence of the glutathione-dependent formaldehyde dehydrogenase from Escherichia coli: a class III alcohol dehydrogenase ⬇️

scientific article published on January 21, 1992

Reformulation of thermodynamic systems with aggregation and theoretical methods for the analysis of ligand binding in proteins with monomer-multimer equilibria.

scientific article published in September 1994

Separation of L-Pro-DL-boroPro into its component diastereomers and kinetic analysis of their inhibition of dipeptidyl peptidase IV. A new method for the analysis of slow, tight-binding inhibition

scientific article published on 01 August 1993

Statistical analysis of data pertaining to complex state systems by stepwise regression with reformulated parameters; Application to spectroscopically monitored hemoglobin oxygen binding data ⬇️

scientific article published on March 9, 1998

Thermodynamic model of cooperativity in a dimeric protein: Unique and independent parameters formulation ⬇️

scientific article published on December 1, 1992

Unique and independent parameters (UIP) formulation for thermodynamic models of complex protein-ligand systems

scientific article published on December 1, 1992

pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5.

scientific article

β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor.

scientific article published in February 2018

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