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List of works by Andrew Weyrich

A sticky story for signal transducer and activator of transcription 3 in platelets.

scientific article published on 24 December 2012

A tour through the transcriptional landscape of platelets

scientific article

A yeast PAF acetylhydrolase ortholog suppresses oxidative death.

scientific article published on 3 May 2008

Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice

scientific journal article

Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events.

scientific article

Arf6 arbitrates fibrinogen endocytosis.

scientific article published on March 2016

Assessing protein synthesis by platelets

scientific article published on 01 January 2012

Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets

scientific article

Baseline red blood cell osmotic fragility does not predict the degree of post-LVAD hemolysis.

scientific article

Cationic PAMAM dendrimers aggressively initiate blood clot formation.

scientific article

Cationic PAMAM dendrimers disrupt key platelet functions.

scientific article

Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes

scientific article

Ceramide generation in situ alters leukocyte cytoskeletal organization and beta 2-integrin function and causes complete degranulation.

scientific article published on 12 November 2001

Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.

scientific article

Classification of venous thromboembolism (VTE). The clot is hot: inflammation, myeloid leukocytes, and venous thromboembolism

scientific article published on 01 November 2005

Clots Are Potent Triggers of Inflammatory Cell Gene Expression: Indications for Timely Fibrinolysis.

scientific article published on 3 August 2017

Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants

scientific article published on 14 September 2016

Comparative genomics: fishing nets hemostatic catch

scientific article published on 01 May 2009

Coordinate expression of transcripts and proteins in platelets.

scientific article published in June 2013

Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.

scientific article published in November 2017

Dengue induces platelet activation, mitochondrial dysfunction and cell death through mechanisms that involve DC-SIGN and caspases ⬇️

scientific article published on May 1, 2013

Dengue virus pirates human platelets

scientific article published in July 2015

Deubiquitinases Modulate Rapid Functional Responses in Platelets

scientific article published in December 2015

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.

scientific article

Different mechanisms preserve translation of programmed cell death 8 and JunB in virus-infected endothelial cells.

scientific article

Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets

scientific article published on 01 September 2001

Endogenous LINE-1 (Long Interspersed Nuclear Element-1) Reverse Transcriptase Activity in Platelets Controls Translational Events Through RNA-DNA Hybrids

scientific article published on 4 January 2018

Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility.

scientific article published on 13 October 2004

Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils

scientific article published on 01 November 1997

Evaluating the relevance of the platelet transcriptome.

scientific article

Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling

scientific article

Fibrinogen selects selectins

scientific article published on 01 July 2009

Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation

scientific article published on 01 January 2003

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes.

scientific article

Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.

scientific article

Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency

scientific article

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes

scientific article published on 14 February 2019

Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.

scientific article published on 29 June 2017

Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging.

scientific article published on 22 November 2017

Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.

scientific article

Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3

scientific article published on 05 February 2019

Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.

scientific article published on 12 February 2009

In vivo platelet activation in critically ill patients with primary 2009 influenza A(H1N1)

scientific article

Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets.

scientific article

Integrins regulate the intracellular distribution of eukaryotic initiation factor 4E in platelets. A checkpoint for translational control.

scientific article published on 28 June 2001

Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesis

scientific article published on 10 August 2007

Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.

scientific article published on 19 May 2006

Lessons from rare maladies: leukocyte adhesion deficiency syndromes

scientific article published on January 2013

Leukocyte adhesion deficiency‐I variant syndrome (LAD‐Iv, LAD‐III): Molecular characterization of the defect in an index family ⬇️

scientific article published on December 3, 2011

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

scientific article published on 01 May 2019

Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events.

scientific article

Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration.

scientific article published on 24 January 2013

Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium

scientific article published on 01 August 1993

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome

scientific article (publication date: 17 July 2011)

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation.

scientific article published on 06 September 2016

Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.

scientific article

New roles for an old drug: inhibition of gene expression by dipyridamole in platelet-leukocyte aggregates.

scientific article

Non-genomic activities of retinoic acid receptor alpha control actin cytoskeletal events in human platelets.

scientific article

Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.

scientific article

Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function

scientific article published on 01 May 2002

PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids.

scientific article published on 24 April 2009

PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.

scientific article

Pegasparaginase treatment alters thrombin generation by modulating the protein C and S system in acute lymphoblastic leukaemia/lymphoma.

scientific article published on 18 July 2015

Physiological concentrations of nitric oxide do not elicit an acute negative inotropic effect in unstimulated cardiac muscle

scientific article published on 01 October 1994

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

scientific article

Platelet precursors display bipolar behavior.

scientific article published on November 2010

Platelet-Monocyte Aggregates and C-Reactive Protein are Associated with VTE in Older Surgical Patients

scientific article published on 07 June 2016

Platelet-monocyte aggregate formation and mortality risk in older patients with severe sepsis and septic shock

scientific article

Platelets as Central Mediators of Systemic Inflammatory Responses ⬇️

scientific article published on November 11, 2010

Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases

scientific article

Platelets in atherothrombosis: new and evolving roles.

scientific article published on January 2007

Platelets in lung biology.

scientific article published on October 2012

Platelets, endothelial cells, inflammatory chemokines, and restenosis: complex signaling in the vascular play book

scientific article published on 01 September 2002

Platelets: more than a sack of glue

scientific article

Platelets: signaling cells in the immune continuum.

scientific article

Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

scientific article

Platelet–leukocyte interactions link inflammatory and thromboembolic events in ischemic stroke ⬇️

scientific article published on October 1, 2010

Polyubiquinated protein depots in platelets and megakaryocytes from patients with ANKRD26-RT.

scientific article

Proteasome function is required for platelet production

scientific article (publication date: September 2014)

Protein degradation systems in platelets

scientific article

Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs

scientific article published on 01 May 1994

RASA3 is a critical inhibitor of RAP1-dependent platelet activation

scientific article

Regulation of the genetic code in megakaryocytes and platelets

scientific article published on June 2015

Reply to Schattner.

scientific article published on October 2013

Retinoic acid receptor-α regulates synthetic events in human platelets

scientific article published on 5 October 2017

Ribosomes in platelets protect the messenger.

scientific article

Sepsis alters the transcriptional and translational landscape of human and murine platelets

scientific article published on 31 July 2019

Signal-dependent protein synthesis by activated platelets: new pathways to altered phenotype and function.

scientific article published on March 2008

Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.

scientific article

Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets ⬇️

scientific article published on May 12, 1998

Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells.

scientific article

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets ⬇️

scientific article published on January 28, 2011

Superoxide Dismutase 2 is dispensable for platelet function.

scientific article published on 3 August 2017

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.

scientific article

T granules in human platelets function in TLR9 organization and signaling ⬇️

scientific article published on August 20, 2012

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10.

scientific article published on 15 February 2017

TGFBIp: more than meets the eye?

scientific article published on 01 December 2009

The evolving role of platelets in inflammation.

scientific article

The role of L-arginine in ameliorating reperfusion injury after myocardial ischemia in the cat ⬇️

scientific article published on 01 July 1992

The septic milieu triggers expression of spliced tissue factor mRNA in human platelets.

scientific article

Translational control in endothelial cells.

scientific article published in June 2007

Translational control of JunB, an AP‐1 transcription factor, in activated human endothelial cells ⬇️

scientific article published on July 1, 2013

VTE Incidence and Risk Factors in Patients With Severe Sepsis and Septic Shock

scientific article

Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques.

scientific article published on 16 December 2011

mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.

scientific article published on 16 November 2006

miR-15a-5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway

scientific article published on 25 February 2019

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