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List of works by Robert Gilchrist

A Hyperandrogenic Environment Causes Intrinsic Defects That Are Detrimental to Follicular Dynamics in a PCOS Mouse Model

scientific article published on 01 March 2019

A sensitive method for the separation and quantification of low-level adenine nucleotides using porous graphitic carbon-based liquid chromatography and tandem mass spectrometry

scientific article

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

scientific article

Activation of 5' adenosine monophosphate-activated protein kinase blocks cumulus cell expansion through inhibition of protein synthesis during in vitro maturation in Swine.

scientific article published on 16 July 2014

Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells.

scientific article published on 13 October 2004

Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply.

scientific article published on 19 February 2014

Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells.

scientific article published on 22 June 2005

Anti-Müllerian hormone as a predictor of IVF outcome.

scientific article

Are human oocytes from stem cells next?

scientific article published in December 2016

BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.

scientific article published in March 2017

Bidirectional communication between cumulus cells and the oocyte: Old hands and new players?

scientific article published on 21 April 2016

Bone morphogenetic protein 15 and fibroblast growth factor 10 enhance cumulus expansion, glucose uptake, and expression of genes in the ovulatory cascade during in vitro maturation of bovine cumulus-oocyte complexes.

scientific article published on 14 June 2013

Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence

scientific article

Bovine Cumulus Cell-Oocyte Gap Junctional Communication During In Vitro Maturation in Response to Manipulation of Cell-Specific Cyclic Adenosine 3′,5′-Monophosophate Levels1 ⬇️

scientific article published on October 20, 2003

Capacitation IVM improves cumulus function and oocyte quality in minimally stimulated mice

scientific article published on 31 October 2019

Changes in follicle-stimulating hormone and follicle populations during the ovarian cycle of the common marmoset.

scientific article

Chromosome constitution of human embryos generated after in vitro maturation including 3-isobutyl-1-methylxanthine in the oocyte collection medium.

scientific article published on 4 December 2014

Comparison of oocyte factors and transforming growth factor-beta in the regulation of DNA synthesis in bovine granulosa cells.

scientific article published in March 2003

Cumulin and FSH Cooperate to Regulate Inhibin B and Activin B Production by Human Granulosa-Lutein Cells In Vitro

article

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

scientific article

Cumulus expansion and glucose utilisation by bovine cumulus-oocyte complexes during in vitro maturation: the influence of glucosamine and follicle-stimulating hormone.

scientific article

Differences in the participation of TGFB superfamily signalling pathways mediating porcine and murine cumulus cell expansion.

scientific article published on 6 September 2011

Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oocyte meiotic maturation.

scientific article

Effect of epidermal growth factor-like peptides on the metabolism of in vitro- matured mouse oocytes and cumulus cells

scientific article published on 6 March 2014

Effect of pre-in vitro maturation with cAMP modulators on the acquisition of oocyte developmental competence in cattle

scientific article published on 2 March 2018

Effectiveness and safety of in vitro maturation of oocytes versus in vitro fertilisation in women with high antral follicle count: study protocol for a randomised controlled trial

scientific article published on 09 December 2018

Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development

scientific article published on 11 January 2014

Effects of ovarian stimulation, with and without human chorionic gonadotrophin, on oocyte meiotic and developmental competence in the marmoset monkey (Callithrix jacchus).

scientific article published on 21 August 2007

Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice.

scientific article published on 12 October 2007

Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation.

scientific article

Extending prematuration with cAMP modulators enhances the cumulus contribution to oocyte antioxidant defence and oocyte quality via gap junctions.

scientific article published on 22 February 2016

Extra-ovarian expression and activity of growth differentiation factor 9.

scientific article

Failure to launch: aberrant cumulus gene expression during oocyte in vitro maturation

scientific article

Fibroblast growth factor 17 and bone morphogenetic protein 15 enhance cumulus expansion and improve quality of in vitro-produced embryos in cattle.

scientific article

Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function.

scientific article

Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells.

scientific article published on 24 August 2010

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

scientific article published on 6 May 2013

Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence.

scientific article published on 4 April 2013

Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of heat shock protein 90.

scientific article published on 7 April 2014

IVM media are designed specifically to support immature cumulus-oocyte complexes not denuded oocytes that have failed to respond to hyperstimulation.

scientific article published on 30 June 2011

Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.

scientific article

Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies

scientific article published on 18 May 2016

In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies

scientific article published on 13 February 2018

Increased gonadotrophin stimulation does not improve IVF outcomes in patients with predicted poor ovarian reserve.

scientific article published on 30 October 2008

Influence of oocyte-secreted factors and culture duration on the metabolic activity of bovine cumulus cell complexes.

scientific article

MHC Class II DRB genotyping is highly predictive of in-vitro alloreactivity in the common marmoset.

scientific article published on 24 July 2006

Meiotic competence of marmoset monkey oocytes is related to follicle size and oocyte-somatic cell associations.

scientific article published in June 1995

Metabolic differences in bovine cumulus-oocyte complexes matured in vitro in the presence or absence of follicle-stimulating hormone and bone morphogenetic protein 15.

scientific article published on 11 October 2012

Mode of oocyte maturation affects EGF-like peptide function and oocyte competence.

scientific article published on 16 April 2013

Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes.

scientific article

Mouse oocyte mitogenic activity is developmentally coordinated throughout folliculogenesis and meiotic maturation.

scientific article published in December 2001

Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide

scientific article published on 29 May 2018

Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.

scientific article published on 20 March 2017

Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes

scientific article

Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells

scientific article published on 03 April 2019

Oocyte expression, secretion and somatic cell interaction of mouse bone morphogenetic protein 15 during the peri-ovulatory period

scientific article published on 19 February 2014

Oocyte induction of EGF responsiveness in somatic cells is associated with the acquisition of porcine oocyte developmental competence.

scientific article published on 7 April 2015

Oocyte maturation and quality: role of cyclic nucleotides

scientific article

Oocyte maturation: emerging concepts and technologies to improve developmental potential in vitro.

scientific article published on 7 November 2006

Oocyte-secreted factor(s) determine functional differences between bovine mural granulosa cells and cumulus cells.

scientific article published in September 2000

Oocyte-secreted factors enhance oocyte developmental competence.

scientific article published on 17 June 2006

Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality.

scientific article published on 05 January 2008

Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins.

scientific article published in November 2005

Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism

scientific article published on 05 December 2019

Pathogenesis of Reproductive and Metabolic PCOS Traits in a Mouse Model

scientific article published in 2021

Pioneering contributions by Robert Edwards to oocyte in vitro maturation (IVM).

scientific article published on 15 November 2013

Pre-maturation with cAMP modulators in conjunction with EGF-like peptides during in vitro maturation enhances mouse oocyte developmental competence.

scientific article published on 22 February 2014

Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro-matured mouse oocytes.

scientific article published on 25 June 2014

Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes.

scientific article

Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach.

scientific article published on 23 December 2017

Random start or emergency IVF/in vitro maturation: a new rapid approach to fertility preservation

scientific article published on June 2016

Redox and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone

scientific article

Reevaluation and evolution of the simulated physiological oocyte maturation system.

scientific article

Regulation of gap junctions in porcine cumulus-oocyte complexes: contributions of granulosa cell contact, gonadotropins, and lipid rafts.

scientific article

Regulation of sheep oocyte maturation using cAMP modulators.

scientific article published on 25 October 2012

Role of oocyte-secreted growth differentiation factor 9 in the regulation of mouse cumulus expansion.

scientific article published on 10 March 2005

Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15.

scientific article

Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15 ⬇️

scientific article published on September 12, 2011

Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes ⬇️

scientific article published on September 24, 2010

Somatic guidance for the oocyte.

scientific article

TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells.

scientific article published on 15 June 2012

Temporal effects of exogenous oocyte-secreted factors on bovine oocyte developmental competence during IVM.

scientific article published in January 2011

The common marmoset as a novel preclinical transplant model: identification of new MHC class II DRB alleles and prediction of in vitro alloreactivity

scientific article published on 01 April 2007

The definition of IVM is clear-variations need defining.

scientific article published on 22 September 2016

The effect of peri-conception hyperglycaemia and the involvement of the hexosamine biosynthesis pathway in mediating oocyte and embryo developmental competence.

scientific article published on 27 January 2014

The epidermal growth factor network: role in oocyte growth, maturation and developmental competence.

scientific article

The pivotal role of glucose metabolism in determining oocyte developmental competence.

scientific article published on 20 January 2010

The promise of in vitro maturation in assisted reproduction and fertility preservation.

scientific article published on 04 January 2011

The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: a systematic review.

scientific article

Transcriptomic signature of the follicular somatic compartment surrounding an oocyte with high developmental competence

scientific article published on 28 July 2017

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