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List of works by Collen Masimirembwa

A Simple Phosphate-Buffered-Saline-Based Extraction Method Improves Specificity of HIV Viral Load Monitoring Using Dried Blood Spots

scientific article

A cost effective RFLP method to genotype Solute carrier organic anion 1B1 (SLCO1B1) c.1929A>C (p.Leu643Phe, rs34671512); a variant with potential effect on rosuvastatin pharmacokinetics.

scientific article

African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development

scientific article published on 20 February 2017

An African-specific profile of pharmacogene variants for rosuvastatin plasma variability: limited role for SLCO1B1 c.521T>C and ABCG2 c.421A>C

scholarly article by Nyarai Desiree Soko et al published 13 August 2018 in The Pharmacogenomics Journal

An Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016.

scientific article published in April 2016

Biotechnology Innovators To Convene in Cape Town, South Africa: Pharmacogenetics and Precision Medicine Conference (April 7-9, 2016).

scientific article

Biotransformation and biocatalysis: roles and applications in the discovery of antimalarials

scientific article published on December 2012

CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans

article

CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe

scientific article published on 27 March 2015

Characterisation of artemisinin-chloroquinoline hybrids for potential metabolic liabilities

scientific article published on 4 September 2015

Community Based Antiretroviral Treatment in Rural Zimbabwe

scientific article published on 13 September 2017

Cytochrome P450 pharmacogenetics in African populations: implications for public health

scientific article published on 03 March 2014

Drug resistance mutations from whole blood proviral DNA among patients on antiretroviral drugs in Zimbabwe

scientific article published on January 2014

Effect of NIPRISAN® on CYP3A4 activity in vitro

scientific article published on 24 January 2014

Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR.

scientific article

Evaluation of Herbal Medicines: Value Addition to Traditional Medicines Through Metabolism, Pharmacokinetic and Safety Studies

scientific article published on January 2014

Evaluation of the Partec flow cytometer against the BD FACSCalibur system for monitoring immune responses of human immunodeficiency virus-infected patients in Zimbabwe

scientific article published on 31 January 2007

Extracting Molecular Information from African Natural Products to Facilitate Unique African-Led Drug-Discovery Efforts ⬇️

scientific article published on March 1, 2011

Flavin-containing monooxygenase 3 polymorphisms in 13 ethnic populations from Europe, East Asia and sub-Saharan Africa: frequency and linkage analysis

scientific article published on September 2009

Genetic variants of drug metabolizing enzymes and drug transporter (ABCB1) as possible biomarkers for adverse drug reactions in an HIV/AIDS cohort in Zimbabwe.

scientific article published in September 2013

H3Africa and the African life sciences ecosystem: building sustainable innovation

scientific article

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe

scientific article published on 5 December 2007

Identification and Characterization of Reactive Metabolites in Natural Products-Driven Drug Discovery ⬇️

scientific article published on March 23, 2012

Lysosomal trapping of amodiaquine: impact on transport across intestinal epithelia models

scientific article published on September 2008

Might ART Adherence Estimates Be Improved by Combining Biomarker and Self-Report Data?

scientific article

Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR.

scientific article

Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

scientific article

Pharmacogenomics of Rosuvastatin: A Glocal (Global+Local) African Perspective and Expert Review on a Statin Drug

scientific article published on September 2016

Pharmacokinetics of rosuvastatin in 30 healthy Zimbabwean individuals of African ancestry

scientific article published on 23 February 2016

Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity

scientific article published on October 2014

Population Diversity and Pharmacogenomics in Africa

article

Practical Approach to Biobanking in Zimbabwe: Establishment of an Inclusive Stakeholder Framework

scientific article published on 15 April 2016

Rolling out Efavirenz for HIV Precision Medicine in Africa: Are We Ready for Pharmacovigilance and Tackling Neuropsychiatric Adverse Effects?

scientific article published on 14 September 2016

Simulation of metabolism-based herb-drug interaction: towards safe and efficacious use of NIPRD-AM1

scientific article

The Evaluation of CYP2B6 Inhibition by Artemisinin Antimalarials in Recombinant Enzymes and Human Liver Microsomes ⬇️

scientific article published on January 1, 2012

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries

scientific article published on 10 October 2018

The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone

scientific article published on 10 February 2014

The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux

scientific article published on 3 June 2006

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