Search filters

List of works by Maria Luz Martinez Chantar

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

scientific article published on April 2004

A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma ⬇️

scientific article published on March 12, 2013

A morphological method for ammonia detection in liver

scientific article

Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis ⬇️

scientific article published on November 1, 2010

Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice.

scientific article

Alcohol, DNA methylation, and cancer

scientific article

An update on the use of benzoate, phenylacetate and phenylbutyrate ammonia scavengers for interrogating and modifying liver nitrogen metabolism and its implications in urea cycle disorders and liver disease

scientific article published on 18 November 2016

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

scientific article published in January 2000

Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice

scientific article published in Scientific Reports

Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia

scientific article published on 26 November 2010

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

scientific article published on 04 January 2021

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy

article

Corrigendum: Hepatic p63 regulates steatosis via IKKβ/ER stress.

scientific article published on 16 June 2017

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

scientific article published on 17 January 2018

Crystallization and preliminary crystallographic analysis of merohedrally twinned crystals of MJ0729, a CBS-domain protein from Methanococcus jannaschii.

scientific article published on 7 June 2008

Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators ⬇️

scientific article published on 06 March 2019

Deregulated neddylation in liver fibrosis

scientific article

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

scientific article

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

scientific article published on 13 December 2020

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

scientific article published in February 2009

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

scientific article published on January 2005

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

scientific article published in November 2003

GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress

scientific article published on 13 May 2020

Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

scientific article published on 8 April 2014

Hepatic p63 regulates steatosis via IKKβ/ER stress

scientific article

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

scientific article published on 23 September 2020

Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.

scientific article

High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice.

scientific article

Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1

scientific article

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.

scientific article published in January 2019

HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis

scientific journal article

Human antigen R contributes to hepatic stellate cell activation and liver fibrosis

scientific article published on 9 October 2012

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

scientific article

Identification of a gene-pathway associated with non-alcoholic steatohepatitis

scientific article published on 30 November 2006

Impaired liver regeneration in mice lacking glycine N-methyltransferase.

scientific article published on August 2009

Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA.

scientific article

Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease.

scientific article published on 20 May 2015

Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans

scientific article published on 24 September 2018

Liver Angiopoietin-2 is a key predictor of de novo or recurrent hepatocellular cancer after HCV direct-acting antivirals

scientific article published on 31 March 2018

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice ⬇️

scientific article published on October 1, 2010

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

scientific article published on 26 January 2017

Metabolomics Discloses Potential Biomarkers for the Noninvasive Diagnosis of Idiopathic Portal Hypertension

scientific article published on 19 February 2013

Metabolomics as a diagnostic tool for idiopathic non-cirrhotic portal hypertension

scientific article published on 23 September 2015

Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis

scientific article published on 10 February 2019

Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts.

scientific article published on 4 May 2018

Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

scientific article published on 25 June 2019

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

scientific article published on 28 June 2013

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

scientific article published in January 2014

Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease.

scientific article published on October 2006

Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

scientific article published on 19 September 2015

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

scientific article published on 20 September 2018

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.

scientific article published on 24 August 2017

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

scientific article

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

scientific article published on 27 November 2020

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation

scientific article published in March 2012

NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.

scientific article published on 20 March 2015

Neddylation, a novel paradigm in liver cancer

scientific article published on 30 June 2018

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.

scientific article published on 09 February 2015

Non-alcoholic steatohepatitis and animal models: understanding the human disease.

scientific article

Nonalcoholic steatohepatitis, animal models, and biomarkers: what is new?

scientific article published on 01 January 2010

Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants

scientific article

Nutraceutical Properties of Polyphenols against Liver Diseases

scientific article published on 15 November 2020

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

scientific article published on 15 March 2012

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

scientific article published on 21 June 2020

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease

scientific article published on 18 March 2019

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

scientific article published on 06 June 2019

Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells

scientific article published on 16 December 2016

Purification, crystallization and preliminary X-ray diffraction analysis of the CBS-domain pair from the Methanococcus jannaschii protein MJ0100

scientific article

Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults

scientific article

Regulation of rat liver S-adenosylmethionine synthetase during septic shock: role of nitric oxide

scientific article published on 01 February 1997

Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease

scientific article published on 9 January 2015

Role of Aramchol in steatohepatitis and fibrosis in mice.

scientific article published on 4 October 2017

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

scientific article published on 18 November 1996

S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.

scientific article

S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.

scientific article published on 18 November 2010

S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus-expressing cells

scientific article published on April 2016

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

scientific article published in February 2002

S-adenosylmethionine levels regulate the schwann cell DNA methylome.

scientific article published on March 2014

S-adenosylmethionine metabolism and liver disease.

scientific article published on March 2013

S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase

scientific article published on 01 July 2006

SAMe and HuR in liver physiology: usefulness of stem cells in hepatic differentiation research

scientific article

SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.

scientific article published on 31 March 2014

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

scientific article published on 01 November 2019

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

scientific article published on 26 December 2018

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

scientific article

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.

scientific article published in July 2015

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

scientific article published on 14 February 2019

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

scientific article published on 03 July 2020

Sirtuin 1 regulation of developmental genes during differentiation of stem cells.

scientific article

Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

scientific article published on 07 June 2002

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

scientific article

Stratification and therapeutic potential of PML in metastatic breast cancer

scientific article

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

scientific article

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

scientific article

Systems biology for hepatologists

scientific article

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

scientific article

Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis

scientific article

The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

scientific article published on 01 October 2019

The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.

scientific article

The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?

scientific article

The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development.

scientific article published in April 2012

The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant

scientific article published on 6 September 2017

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.

scientific article

The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis

scientific article published on 11 April 2015

The role of stem cells/progenitor cells in liver carcinogenesis in glycine N-methyltransferase deficient mice.

scientific article published on 19 January 2010

Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin.

scientific article

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.

scientific article published on 28 June 2017

miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

scientific article published on 16 August 2019

Paulina is supported by:

About Paulina

Help