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List of works by Philip Hanawalt

24 Interference of PNA binding to the non-template strand with transcription supports the general model for transcription blockage by R-loop formation

scientific article published on May 2015

A balanced perspective on unbalanced growth and thymineless death

scientific article published on 5 June 2015

A cut above: discovery of an alternative excision repair pathway in bacteria

scientific article

A novel XPD mutation in a compound heterozygote; the mutation in the second allele is present in three homozygous patients with mild sun sensitivity ⬇️

scientific article published on July 23, 2012

A novel mode for transcription inhibition mediated by PNA-induced R-loops with a model in vitro system.

scientific article published on 18 January 2018

A triplex-forming sequence from the human c-MYC promoter interferes with DNA transcription

scientific article published on 04 September 2007

Altered minor-groove hydrogen bonds in DNA block transcription elongation by T7 RNA polymerase

scientific article

Anchoring Nascent RNA to the DNA Template Could Interfere with Transcription ⬇️

scientific article published on February 2, 2011

Behavior of T7 RNA polymerase and mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA.

scientific article published on 26 June 2003

Building on the past, shaping the future: The environmental mutagenesis and genomics society ⬇️

scientific article published on February 26, 2013

Clustered sites of DNA repair synthesis during early nucleotide excision repair in ultraviolet light-irradiated quiescent human fibroblasts

scientific article published in June 2002

Coincidentally, this first issue marks the 50th anniversary of the seminal discovery of the excision-repair of damaged DNA. Preface.

scientific article

Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells

scientific article

Comparative TFIIS-mediated transcript cleavage by mammalian RNA polymerase II arrested at a lesion in different transcription systems

scientific journal article

Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli

scientific article

Cutting-edge Perspectives in Genomic Maintenance III: Preface

scientific article published on 31 May 2016

Cutting-edge Perspectives in Genomic Maintenance. Preface

scientific article published on 16 June 2015

Cutting-edge perspectives in genomic maintenance IV

scientific article published on 24 June 2017

Cutting-edge perspectives in genomic maintenance V

scientific article published on 25 September 2018

Cutting-edge perspectives in genomic maintenance VI

scientific article published on 05 August 2019

DNA repair in terminally differentiated cells

scientific article

DNA repair: From molecular mechanism to human disease

scientific article published on 01 August 2006

DNA sequences that interfere with transcription: implications for genome function and stability.

scientific article published on 23 August 2013

DNA slip-outs cause RNA polymerase II arrest in vitro : potential implications for genetic instability ⬇️

scientific article published on June 11, 2011

Density matters: the semiconservative replication of DNA

scientific article

Differential incorporation of halogenated deoxyuridines during UV-induced DNA repair synthesis in human cells

scientific article published in March 2005

Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II.

scientific article published in May 2004

Emerging links between premature ageing and defective DNA repair

scientific article published on 25 March 2008

Four decades of DNA repair: from early insights to current perspectives

scientific article

Functional characterization of global genomic DNA repair and its implications for cancer.

scientific article published on November 2003

G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II.

scientific article published on 20 February 2008

Growing up with DNA repair and joining the EMS.

scientific article published in October 2010

Historical perspective on the DNA damage response

scientific article

Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts

scientific article published on 29 August 2005

Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme

scientific article

In memory of John Bruce Hays (1937-2014).

scientific article published in April 2014

In vivo assays for transcription-coupled repair.

scientific article published on January 2006

Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase

scientific article published on 9 April 2008

Intrinsic genomic instability from naturally occurring DNA structures: An introduction to the special issue

scientific article published in April 2009

Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II.

scientific article

Mechanisms and implications of transcription blockage by guanine-rich DNA sequences.

scientific article

Mechanistic understanding of cellular responses to genomic stress

scientific article published on 26 December 2019

Modulation of Cytotoxicity by Transcription-Coupled Nucleotide Excision Repair Is Independent of the Requirement for Bioactivation of Acylfulvene.

scientific article published on 11 January 2017

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

scientific article published on 20 January 2016

New applications of the Comet assay: Comet-FISH and transcription-coupled DNA repair

scientific article published on 17 January 2008

Nucleotide excision repair activity varies among murine spermatogenic cell types

scientific article

Nucleotide excision repair phenotype of human acute myeloid leukemia cell lines at various stages of differentiation

scientific article published on 4 August 2006

PNA binding to the non-template DNA strand interferes with transcription, suggesting a blockage mechanism mediated by R-loop formation

scientific article

Paradigms for the three rs: DNA replication, recombination, and repair

scientific article published on December 2007

Peptide nucleic acid (PNA) binding and its effect on in vitro transcription in friedreich's ataxia triplet repeats

scientific article published on April 2009

Photobiological Origins of the Field of Genomic Maintenance

scientific article

Photosensitive human syndromes

scientific article

R-loop generation during transcription: Formation, processing and cellular outcomes

scientific article published on 25 August 2018

RecA-Dependent Recovery of Arrested DNA Replication Forks ⬇️

scientific article published on January 1, 2003

Research collaborations: trial, trust, and truth

scientific article published on September 2006

Role of DNA replication and repair in thymineless death in Escherichia coli

scientific article

Role of RecA and the SOS response in thymineless death in Escherichia coli

scientific article

Strong transcription blockage mediated by R-loop formation within a G-rich homopurine-homopyrimidine sequence localized in the vicinity of the promoter

scientific article

Subpathways of nucleotide excision repair and their regulation

scientific article

The awakening of DNA repair at Yale

scientific article published on 13 December 2013

Thymineless Death Lives On: New Insights into a Classic Phenomenon

scientific article published on 07 August 2015

Thymineless death is associated with loss of essential genetic information from the replication origin

scientific article

Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae

scientific article published on 3 March 2006

Topology and kinetics of R-loop formation

scientific article published in 2022

Transcription Blockage by Bulky End Termini at Single-Strand Breaks in the DNA Template: Differential Effects of 5′ and 3′ Adducts ⬇️

scientific article published on October 24, 2012

Transcription Inhibition by PNA-Induced R-Loops

scientific article published on 01 January 2020

Transcription arrest at a lesion in the transcribed DNA strand in vitro is not affected by a nearby lesion in the opposite strand

scientific article published on 19 March 2003

Transcription arrest at an abasic site in the transcribed strand of template DNA.

scientific article

Transcription blockage by homopurine DNA sequences: role of sequence composition and single-strand breaks.

scientific article published on 28 December 2012

Transcription blockage by stable H-DNA analogs in vitro.

scientific article

Transcription coupled nucleotide excision repair in Escherichia coli can be affected by changing the arginine at position 529 of the beta subunit of RNA polymerase.

scientific article published on 25 May 2007

Transcription domain-associated repair in human cells

scientific article

Transcription-coupled DNA repair in prokaryotes

scientific article published on January 2012

Transcription-coupled DNA repair: two decades of progress and surprises

scientific article (publication date: December 2008)

Transcription-coupled nucleotide excision repair of a gene transcribed by bacteriophage T7 RNA polymerase in Escherichia coli

scientific article

Transcriptional inhibition by an oxidized abasic site in DNA.

scientific article published in February 2006

Tribute to Sam Wilson: Shining a light on base excision DNA repair

scientific article published on 01 September 2020

Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers

scientific article

When parsimony backfires: neglecting DNA repair may doom neurons in Alzheimer's disease

scientific article

When transcription goes on Holliday: Double Holliday junctions block RNA polymerase II transcription in vitro

scientific article published on 3 December 2016

Who's on first in the cellular response to DNA damage? ⬇️

scientific article published on May 1, 2003

p53 controls global nucleotide excision repair of low levels of structurally diverse benzo(g)chrysene-DNA adducts in human fibroblasts

scientific article published in September 2002

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