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List of works by Aristoteles A N Giagounidis

A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS ⬇️

scientific article published on February 16, 2011

A patient with Fechtner syndrome successfully treated with romiplostim ⬇️

scientific article published on January 25, 2012

A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

scientific article published on 13 July 2011

Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA

scientific article published on 9 June 2017

Activity of the oral mitogen-activated protein kinase kinase inhibitor trametinib in RAS-mutant relapsed or refractory myeloid malignancies

scientific article published on 18 March 2016

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

scientific article

Azacitidine for treatment of patients with myelodysplastic syndromes (MDS): practical recommendations of the German MDS Study Group

scientific article published on 22 June 2010

Biological and prognostic significance of chromosome 5q deletions in myeloid malignancies

scientific article

CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q).

scientific article

Causes of death in 2877 patients with myelodysplastic syndromes

scientific article

Change of prognosis of patients with myelodysplastic syndromes during the last 30 years

scientific article published on 15 April 2015

Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q).

scientific article

Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System ⬇️

scientific article published on April 25, 2011

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

scientific article

Concomitant Non-Small Cell Lung Cancer and Hairy Cell Leukemia in a Patient Harboring BRAF-V600E Mutation in Both Tissues: A Case Report.

scientific article published in January 2018

Current treatment algorithm for the management of lower-risk MDS.

scientific article published in December 2017

Cytogenetic follow-up by karyotyping and fluorescence in situ hybridization: implications for monitoring patients with myelodysplastic syndrome and deletion 5q treated with lenalidomide ⬇️

scientific article published on November 25, 2010

Dasatinib induces complete remission in a patient with primary cerebral involvement of B-cell chronic lymphocytic leukemia failing chemotherapy

scientific article published on October 2010

Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Gro

scientific article published on 23 November 2015

Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes a

Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

scientific article

Diagnosis and therapy of autoimmune thrombocytopenia. Recommendations of a joint Expert Group of DGHO, DGTI, DTH

scientific article

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

scientific article

Evaluation of bleeding-related episodes in patients with immune thrombocytopenia (ITP) receiving romiplostim or medical standard of care ⬇️

scientific article published on May 5, 2012

Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group

scientific article published on 10 September 2015

Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

scientific article

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes

scientific article published on 8 May 2008

Imatinib compared with chemotherapy as front-line treatment of elderly patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL)

Impact of self-administration of romiplostim by patients with chronic immune thrombocytopenia compared with administration by a healthcare provider

scientific article

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

article

Impact on survival of different treatments for myelodysplastic syndromes (MDS).

scientific article published on 30 January 2009

Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes

scientific article published on 4 March 2016

Isolated Splenic Metastasis from Non-Small-Cell Lung Cancer: A Case Report and Review of the Literature

scientific article published on May 2017

Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes

scientific article published on 10 September 2013

Lenalidomide for del(5q) and Non-del(5q) Myelodysplastic Syndromes ⬇️

scientific article published on October 1, 2012

Lenalidomide in the context of complex karyotype or interrupted treatment: case reviews of del(5q)MDS patients with unexpected responses

scientific article

Lenalidomide: a brief review of its therapeutic potential in myelodysplastic syndromes.

scientific article

Leukemia research in Germany: the Competence Network Acute and Chronic Leukemias

scientific article published on 15 March 2016

Long-term follow-up for up to 5 years on the risk of leukaemic progression in thrombocytopenic patients with lower-risk myelodysplastic syndromes treated with romiplostim or placebo in a randomised double-blind trial

scientific article published on 25 January 2018

Long‐term safety and tolerability of romiplostim in patients with primary immune thrombocytopenia: a pooled analysis of 13 clinical trials ⬇️

scientific article published on September 17, 2013

Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation fo

scientific article published on 11 April 2011

Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

scientific article published on September 2017

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes

scientific article

Molecular cytogenetic monitoring from CD34+ peripheral blood cells in myelodysplastic syndromes: first results from a prospective multicenter German diagnostic study

scientific article published on 25 April 2013

Morphology, cytogenetics and classification of MDS.

scientific article published on October 2013

Myelodysplastic syndromes. Diagnosis and therapeutic strategies

scientific article published in November 2002

New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge ⬇️

scientific article published on February 13, 2012

New proposals of the WHO working group (2016) for the diagnosis of myelodysplastic syndromes (MDS): Characteristics of refined MDS types

scientific article published on 27 February 2017

Optimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling

scientific article published in January 2005

Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study

scientific article

Parameters detected by geriatric and quality of life assessment in 195 older patients with myelodysplastic syndromes and acute myeloid leukemia are highly predictive for outcome

scientific article published on 8 August 2012

Patients with del(5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression

scientific article published on 24 October 2009

Peripheral blood cytogenetics allows treatment monitoring and early identification of treatment failure to lenalidomide in MDS patients: results of the LE-MON-5 trial

scientific article

Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes

scientific article published on 12 February 2008

Prognostic indicators and scoring systems for predicting outcome in patients with myelodysplastic syndromes.

scientific article

Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions

scientific article published on 5 July 2017

Prospective validation of the WHO proposals for the classification of myelodysplastic syndromes

scientific article

Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents

scientific article

Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil.

scientific article published on 28 August 2009

Refractory anaemia with excess of blasts (RAEB): analysis of reclassification according to the WHO proposals.

scientific article

Refractory anemia with excess of blasts in transformation: analysis of reclassification according to the WHO proposals

scientific article

Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia

scientific article

Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD antibodies, in the treatment of primary immune thrombocytopenia

scientific article

Safety and tolerability of eltrombopag versus placebo for treatment of thrombocytopenia in patients with advanced myelodysplastic syndromes or acute myeloid leukaemia: a multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial

scientific article

Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease

scholarly article

Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial

scientific article published on 29 July 2013

Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia

scientific article

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes

scientific article published on 05 July 2013

The 5q- syndrome.

scientific article published on January 2008

The Effect of Lenalidomide on Health-Related Quality of Life in Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes: Results From the MDS-005 Study

scientific article published on 30 December 2017

The impact of lenalidomide exposure on response and outcomes in patients with lower-risk myelodysplastic syndromes and del(5q)

scientific article published on 21 September 2018

The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome

scientific article published on 8 June 2005

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts

scientific article

Transfusion Independency and Histological Remission in a Patient with Advanced Primary Myelofibrosis Receiving Iron-Chelation Therapy with Deferasirox

scientific article

Treatment of myelodysplastic syndrome with isolated del(5q) including bands q31-q33 with a combination of all-trans-retinoic acid and tocopherol-alpha: a phase II study

scientific article published on 23 March 2005

Use of romiplostim in a hemodialysis patient with primary immune thrombocytopenia

scientific article

Validation and proposals for a refinement of the WHO 2008 classification of myelodysplastic syndromes without excess of blasts

scientific article

Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

scientific article published on 24 October 2014

Validation of the revised international prognostic scoring system (IPSS-R) in patients with myelodysplastic syndrome: a multicenter study

scientific article

Where Does Lenalidomide Fit in Non-del(5q) MDS?

scientific article published on 14 July 2015

X-linked sideroblastic anemia associated with a novel ALAS2 mutation and unfortunate skewed X-chromosome inactivation patterns

scientific article (publication date: 2006)

p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q).

scientific article

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