List of works - María José Motilva

A new hydroxytyrosol metabolite identified in human plasma: Hydroxytyrosol acetate sulphate

article

Analysis of food polyphenols by ultra high-performance liquid chromatography coupled to mass spectrometry: an overview.

scientific article published on 11 January 2013

Analysis of free hydroxytyrosol in human plasma following the administration of olive oil

scientific article published on 06 February 2016

Antioxidant activity of olive pulp and olive oil phenolic compounds of the arbequina cultivar.

scientific article

Application of dried blood spot cards to determine olive oil phenols (hydroxytyrosol metabolites) in human blood

scientific article published on 15 June 2016

Application of dried spot cards as a rapid sample treatment method for determining hydroxytyrosol metabolites in human urine samples. Comparison with microelution solid-phase extraction

scientific article

Berry-Enriched Diet in Salt-Sensitive Hypertensive Rats: Metabolic Fate of (Poly)Phenols and the Role of Gut Microbiota

scientific article published on 03 November 2019

Beta-Glucan and Phenolic Compounds: Their Concentration and Behavior during in Vitro Gastrointestinal Digestion and Colonic Fermentation of Different Barley-Based Food Products

scientific article published on 17 August 2018

Bioavailability of phenols from a phenol-enriched olive oil

scientific article published on 21 June 2011

Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production.

scientific article

Cardiovascular Benefits of Phenol-Enriched Virgin Olive Oils: New Insights from the Virgin Olive Oil and HDL Functionality (VOHF) Study

scientific article published on 30 July 2018

Complementary phenol-enriched olive oil improves HDL characteristics in hypercholesterolemic subjects. A randomized, double-blind, crossover, controlled trial. The VOHF study

scientific article published on 23 May 2015

Correction to Virgin Olive Oil Enriched with Its Own Phenolics or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects

scientific article published on 14 June 2016

Design, optimization and validation of genes commonly used in expression studies on DMH/AOM rat colon carcinogenesis model

article

Determinants of HDL Cholesterol Efflux Capacity after Virgin Olive Oil Ingestion: Interrelationships with Fluidity of HDL Monolayer.

scientific article published on 8 September 2017

Development of a Phenol-Enriched Olive Oil with Both Its Own Phenolic Compounds and Complementary Phenols from Thyme

article

Development of a phenol-enriched olive oil with phenolic compounds from olive cake.

scientific article published on October 2010

Distribution of procyanidins and their metabolites in rat plasma and tissues after an acute intake of hazelnut extract.

scientific article published on 5 September 2011

Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.

scientific article published on 11 July 2012

Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats.

scientific article published on 5 May 2015

Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats.

scientific article

Effect of daily intake of pomegranate juice on fecal microbiota and feces metabolites from healthy volunteers.

scientific article published on 29 July 2015

Effect of fat content on the digestibility and bioaccessibility of cocoa polyphenol by an in vitro digestion model.

scientific article published in July 2009

Effect of the Maturation Process of the Olive Fruit on the Phenolic Fraction of Drupes and Oils from Arbequina, Farga, and Morrut Cultivars

scientific article published on 01 September 2004

Effect of the Technological and Agronomical Factors on Pigment Transfer during Olive Oil Extraction

scientific article published on 19 June 2007

Effect of the co-occurring components from olive oil and thyme extracts on the antioxidant status and its bioavailability in an acute ingestion in rats

scientific article published on 01 April 2014

Effect of the co-occurring olive oil and thyme extracts on the phenolic bioaccessibility and bioavailability assessed by in vitro digestion and cell models.

scientific article published on 30 October 2013

Effect of the long-term regular intake of virgin olive oil on the phenolic metabolites in human fasting plasma.

scientific article published on 11 March 2010

Effect of virgin olive oil and thyme phenolic compounds on blood lipid profile: implications of human gut microbiota.

scientific article published on 5 November 2015

Effects of extracts from bean (Phaseolus vulgaris) and field bean (Vicia faba) varieties on intestinal D-glucose transport in rat in vivo

scientific article published on 01 March 1983

Effects of functional olive oil enriched with its own phenolic compounds on endothelial function in hypertensive patients. A randomised controlled trial.

scientific article published on 06 July 2014

Endothelial Cells Deconjugate Resveratrol Metabolites to Free Resveratrol: A Possible Role in Tissue Factor Modulation

scientific article published on 02 January 2019

Enrichment of Refined Olive Oil with Phenolic Compounds: Evaluation of Their Antioxidant Activity and Their Effect on the Bitter Index

scientific article published on 01 August 2006

Exploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells.

scientific article published on 28 October 2016

Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches.

scientific article

Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells.

scientific article published on 24 June 2017

Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats

scientific article published on 14 March 2013

Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects.

scientific article published on 29 April 2016

Hydroxytyrosol and the Colonic Metabolites Derived from Virgin Olive Oil Intake Induce Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.

scientific article published on 10 January 2017

Hydroxytyrosol: Emerging Trends in Potential Therapeutic Applications

scientific article published on 01 January 2018

Impact of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on the HDL Proteome in Hypercholesterolemic Subjects: A Double Blind, Randomized, Controlled, Cross-Over Clinical Trial (VOHF Study).

scientific article published on 10 June 2015

Impact of dietary supplementation with olive and thyme phenols on alpha-tocopherol concentration in the muscle and liver of adult Wistar rats.

scientific article published on 13 February 2018

Impact of olive oil phenolic concentration on human plasmatic phenolic metabolites.

scientific article published on 25 July 2012

Impact of various factors on pharmacokinetics of bioactive polyphenols: an overview

scientific article published on January 2014

Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil.

scientific article

Improved liquid-chromatography tandem mass spectrometry method for the determination of the bioactive dipeptides, carnosine and anserine: application to analysis in chicken broth.

scientific article published on 23 February 2012

Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass spectrometry.

scientific article published on 30 October 2009

Influence of Phenol-Enriched Olive Oils on Human Intestinal Immune Function.

scientific article published on 11 April 2016

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis

scientific article published on 12 January 2016

Metabolic and Microbial Modulation of the Large Intestine Ecosystem by Non-Absorbed Diet Phenolic Compounds: A Review

scientific article

Metabolites involved in oleuropein accumulation and degradation in fruits of Olea europaea L.: Hojiblanca and Arbequina varieties.

scientific article published on December 2010

Methods for preparing phenolic extracts from olive cake for potential application as food antioxidants.

scientific article published in February 2009

Multicompartmental LC-Q-TOF-Based Metabonomics as an Exploratory Tool to Identify Novel Pathways Affected by Polyphenol-Rich Diets in Mice

scientific article published on 17 June 2011

Nutrikinetic studies of food bioactive compounds: from in vitro to in vivo approaches

scientific article published on 01 July 2015

Olive oil polyphenols enhance the expression of cholesterol efflux related genes in vivo in humans. A randomized controlled trial.

scientific article

Optimisation and validation of analytical methods for the simultaneous extraction of antioxidants: Application to the analysis of tomato sauces

scientific article published on 09 May 2014

Phenol-Enriched Virgin Olive Oil Promotes Macrophage-Specific Reverse Cholesterol Transport In Vivo

scientific article published on 03 August 2020

Phenol-enriched olive oils improve HDL antioxidant content in hypercholesterolemic subjects. A randomized, double-blind, cross-over, controlled trial

scientific article published on 28 September 2017

Phenol-enriched olive oils modify paraoxonase-related variables: A randomized, crossover, controlled trial.

scientific article published on 25 May 2017

Phytochemical Profiles of New Red-Fleshed Apple Varieties Compared with Traditional and New White-Fleshed Varieties.

scientific article published on 13 February 2017

Phytochemical composition and β-glucan content of barley genotypes from two different geographic origins for human health food production.

scientific article published on 7 September 2017

Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications ⬇️

scientific article published on August 29, 2012

Polyphenol rich olive oils improve lipoprotein particle atherogenic ratios and subclasses profile: A randomized, crossover, controlled trial

scientific article published on 15 March 2016

Procyanidins target mesenteric adipose tissue in Wistar lean rats and subcutaneous adipose tissue in Zucker obese rat

scientific article published on 07 March 2013

Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells.

scientific article published on 21 September 2015

Rapid methods to determine procyanidins, anthocyanins, theobromine and caffeine in rat tissues by liquid chromatography-tandem mass spectrometry

scientific article published on 29 March 2011

Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer's Disease

scientific article published on 10 October 2020

Seasonal Variability of the Phytochemical Composition of New Red-Fleshed Apple Varieties Compared with Traditional and New White-Fleshed Varieties

scientific article published on 14 September 2018

Stability and metabolism of Arbutus unedo bioactive compounds (phenolics and antioxidants) under in vitro digestion and colonic fermentation

scientific article published on 20 January 2016

Study of the catabolism of thyme phenols combining in vitro fermentation and human intervention

scientific article

The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects

scientific article published on 21 December 2016

Understanding of human metabolic pathways of different sub-classes of phenols from Arbutus unedo fruit after an acute intake

scientific article published on 01 March 2016

Validation of Dried Blood Spot Cards to Determine Apple Phenolic Metabolites in Human Blood and Plasma After an Acute Intake of Red-Fleshed Apple Snack

scientific article published on 02 November 2018

Validation of determination of plasma metabolites derived from thyme bioactive compounds by improved liquid chromatography coupled to tandem mass spectrometry

scientific article published on 10 August 2012

Virgin Olive Oil Enriched with Its Own Phenols or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects

scientific article published on 26 February 2016

β-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.

scientific article published on 17 April 2012

List of works by María José Motilva

A new hydroxytyrosol metabolite identified in human plasma: Hydroxytyrosol acetate sulphate

Analysis of food polyphenols by ultra high-performance liquid chromatography coupled to mass spectrometry: an overview.

Analysis of free hydroxytyrosol in human plasma following the administration of olive oil

Antioxidant activity of olive pulp and olive oil phenolic compounds of the arbequina cultivar.

Application of dried blood spot cards to determine olive oil phenols (hydroxytyrosol metabolites) in human blood

Application of dried spot cards as a rapid sample treatment method for determining hydroxytyrosol metabolites in human urine samples. Comparison with microelution solid-phase extraction

Berry-Enriched Diet in Salt-Sensitive Hypertensive Rats: Metabolic Fate of (Poly)Phenols and the Role of Gut Microbiota

Beta-Glucan and Phenolic Compounds: Their Concentration and Behavior during in Vitro Gastrointestinal Digestion and Colonic Fermentation of Different Barley-Based Food Products

Bioavailability of phenols from a phenol-enriched olive oil

Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production.

Cardiovascular Benefits of Phenol-Enriched Virgin Olive Oils: New Insights from the Virgin Olive Oil and HDL Functionality (VOHF) Study

Complementary phenol-enriched olive oil improves HDL characteristics in hypercholesterolemic subjects. A randomized, double-blind, crossover, controlled trial. The VOHF study

Correction to Virgin Olive Oil Enriched with Its Own Phenolics or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects

Design, optimization and validation of genes commonly used in expression studies on DMH/AOM rat colon carcinogenesis model

Determinants of HDL Cholesterol Efflux Capacity after Virgin Olive Oil Ingestion: Interrelationships with Fluidity of HDL Monolayer.

Development of a Phenol-Enriched Olive Oil with Both Its Own Phenolic Compounds and Complementary Phenols from Thyme

Development of a phenol-enriched olive oil with phenolic compounds from olive cake.

Distribution of procyanidins and their metabolites in rat plasma and tissues after an acute intake of hazelnut extract.

Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.

Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats.

Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats.

Effect of daily intake of pomegranate juice on fecal microbiota and feces metabolites from healthy volunteers.

Effect of fat content on the digestibility and bioaccessibility of cocoa polyphenol by an in vitro digestion model.

Effect of the Maturation Process of the Olive Fruit on the Phenolic Fraction of Drupes and Oils from Arbequina, Farga, and Morrut Cultivars

Effect of the Technological and Agronomical Factors on Pigment Transfer during Olive Oil Extraction

Effect of the co-occurring components from olive oil and thyme extracts on the antioxidant status and its bioavailability in an acute ingestion in rats

Effect of the co-occurring olive oil and thyme extracts on the phenolic bioaccessibility and bioavailability assessed by in vitro digestion and cell models.

Effect of the long-term regular intake of virgin olive oil on the phenolic metabolites in human fasting plasma.

Effect of virgin olive oil and thyme phenolic compounds on blood lipid profile: implications of human gut microbiota.

Effects of extracts from bean (Phaseolus vulgaris) and field bean (Vicia faba) varieties on intestinal D-glucose transport in rat in vivo

Effects of functional olive oil enriched with its own phenolic compounds on endothelial function in hypertensive patients. A randomised controlled trial.

Endothelial Cells Deconjugate Resveratrol Metabolites to Free Resveratrol: A Possible Role in Tissue Factor Modulation

Enrichment of Refined Olive Oil with Phenolic Compounds: Evaluation of Their Antioxidant Activity and Their Effect on the Bitter Index

Exploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells.

Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches.

Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells.

Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats

Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects.

Hydroxytyrosol and the Colonic Metabolites Derived from Virgin Olive Oil Intake Induce Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.

Hydroxytyrosol: Emerging Trends in Potential Therapeutic Applications

Impact of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on the HDL Proteome in Hypercholesterolemic Subjects: A Double Blind, Randomized, Controlled, Cross-Over Clinical Trial (VOHF Study).

Impact of dietary supplementation with olive and thyme phenols on alpha-tocopherol concentration in the muscle and liver of adult Wistar rats.

Impact of olive oil phenolic concentration on human plasmatic phenolic metabolites.

Impact of various factors on pharmacokinetics of bioactive polyphenols: an overview

Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil.

Improved liquid-chromatography tandem mass spectrometry method for the determination of the bioactive dipeptides, carnosine and anserine: application to analysis in chicken broth.

Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass spectrometry.

Influence of Phenol-Enriched Olive Oils on Human Intestinal Immune Function.

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis

Metabolic and Microbial Modulation of the Large Intestine Ecosystem by Non-Absorbed Diet Phenolic Compounds: A Review

Metabolites involved in oleuropein accumulation and degradation in fruits of Olea europaea L.: Hojiblanca and Arbequina varieties.

Methods for preparing phenolic extracts from olive cake for potential application as food antioxidants.

Multicompartmental LC-Q-TOF-Based Metabonomics as an Exploratory Tool to Identify Novel Pathways Affected by Polyphenol-Rich Diets in Mice

Nutrikinetic studies of food bioactive compounds: from in vitro to in vivo approaches

Olive oil polyphenols enhance the expression of cholesterol efflux related genes in vivo in humans. A randomized controlled trial.

Optimisation and validation of analytical methods for the simultaneous extraction of antioxidants: Application to the analysis of tomato sauces

Phenol-Enriched Virgin Olive Oil Promotes Macrophage-Specific Reverse Cholesterol Transport In Vivo

Phenol-enriched olive oils improve HDL antioxidant content in hypercholesterolemic subjects. A randomized, double-blind, cross-over, controlled trial

Phenol-enriched olive oils modify paraoxonase-related variables: A randomized, crossover, controlled trial.

Phytochemical Profiles of New Red-Fleshed Apple Varieties Compared with Traditional and New White-Fleshed Varieties.

Phytochemical composition and β-glucan content of barley genotypes from two different geographic origins for human health food production.

Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications ⬇️

Polyphenol rich olive oils improve lipoprotein particle atherogenic ratios and subclasses profile: A randomized, crossover, controlled trial

Procyanidins target mesenteric adipose tissue in Wistar lean rats and subcutaneous adipose tissue in Zucker obese rat

Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells.

Rapid methods to determine procyanidins, anthocyanins, theobromine and caffeine in rat tissues by liquid chromatography-tandem mass spectrometry

Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer's Disease

Seasonal Variability of the Phytochemical Composition of New Red-Fleshed Apple Varieties Compared with Traditional and New White-Fleshed Varieties

Stability and metabolism of Arbutus unedo bioactive compounds (phenolics and antioxidants) under in vitro digestion and colonic fermentation

Study of the catabolism of thyme phenols combining in vitro fermentation and human intervention

The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects

Understanding of human metabolic pathways of different sub-classes of phenols from Arbutus unedo fruit after an acute intake

Validation of Dried Blood Spot Cards to Determine Apple Phenolic Metabolites in Human Blood and Plasma After an Acute Intake of Red-Fleshed Apple Snack

Validation of determination of plasma metabolites derived from thyme bioactive compounds by improved liquid chromatography coupled to tandem mass spectrometry

Virgin Olive Oil Enriched with Its Own Phenols or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects

β-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.