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List of works by James Adjaye

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The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

scientific article published on April 1, 2010
Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

scientific article published on 26 October 2006
Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential

scientific article published on February 1, 2013
Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

scientific article
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

scientific article
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.

scientific article published in February 2014
Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal

scientific article published on 12 October 2006
Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach

scientific article
Functional comparison of chronological and in vitro aging: differential role of the cytoskeleton and mitochondria in mesenchymal stromal cells

scientific article
Preparation of Mouse Embryonic Fibroblast Cells Suitable for Culturing Human Embryonic and Induced Pluripotent Stem Cells

scientific article published on June 21, 2012
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells

scientific article published on January 1, 2010
A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells

scientific article published on 21 May 2010
Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal

scientific article published on 16 May 2007
Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming

scientific article published on September 2011
Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations

scientific article
Cancer stem cells in solid tumors: elusive or illusive?

scientific article
A Strand-Specific Library Preparation Protocol for RNA Sequencing

scientific article published on January 1, 2011
Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks

scientific article published on February 14, 2015
Human skin stem cells and the ageing process

scientific article published on 09 September 2008
A transcriptional roadmap to the induction of pluripotency in somatic cells

scientific article published on June 2010
Comparative Analysis of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells Reveals Current Drawbacks and Possible Strategies for Improved Differentiation

scientific article published on January 24, 2011
The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells

scientific article
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders

scientific article published on 25 January 2017
Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity

scientific article published in December 2008
Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development

scientific article
Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin

scientific article published in October 2005
Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network

scientific article
FGF Inhibition Directs BMP4-Mediated Differentiation of Human Embryonic Stem Cells to Syncytiotrophoblast

scientific article published on August 6, 2012
Comparative proteome and transcriptome analyses of embryonic stem cells during embryoid body-based differentiation

scientific article published on November 2009
Age-related transcriptional changes in gene expression in different organs of mice support the metabolic stability theory of aging

scientific article
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays

scientific article
In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

scientific article published on 15 July 2009
Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes

scientific article
Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures

scientific article
Identification of biomarkers of human skin ageing in both genders. Wnt signalling - a label of skin ageing?

scientific article
Skin and brain age together: The role of hormones in the ageing process

scientific article published on 16 August 2010
Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro

scientific article published on 29 June 2006
Mitochondrial Function in Pluripotent Stem Cells and Cellular Reprogramming

scientific article published on November 19, 2013
A Cyclic AMP Analog, 8-Br-cAMP, Enhances the Induction of Pluripotency in Human Fibroblast Cells

scientific article published on June 1, 2011
Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression

scientific article published on 26 June 2007
Mesenchymal stem cell conditioning promotes rat oligodendroglial cell maturation

scientific article
Human induced pluripotent stem cells—from mechanisms to clinical applications

scientific article published on May 30, 2012
Oct-4 regulates the expression of Stella and Foxj2 at the Nanog locus: implications for the developmental competence of mouse oocytes

scientific article published on 28 May 2009
Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha

scientific article published on 16 June 2016
Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc

scientific article published on 10 October 2011
BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells

scientific article published on September 23, 2013
Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes

scientific article
The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines

scientific article
The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts

scientific article published on 28 February 2012
Concise Review: Current Status and Future Directions on Research Related to Nonalcoholic Fatty Liver Disease

scientific article published on 4 July 2016

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