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List of works by Linzhao Cheng

A Method for Genome Editing in Human Pluripotent Stem Cells

scientific article

A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease

scientific article published on 21 November 2017

A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach

scientific article

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

scientific article

A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells

scientific article published on 26 December 2013

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

scientific article

Acceleration of G(1) cooperates with core binding factor beta-smooth muscle myosin heavy chain to induce acute leukemia in mice.

scientific article published in April 2002

And then there were none: no need for pluripotency factors to induce reprogramming

scientific article

Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models

scientific article published on August 2007

Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells ⬇️

scientific article published on September 14, 2010

Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells

scientific article published on 2 July 2008

Concise review: Human cell engineering: cellular reprogramming and genome editing

scientific article published on January 2012

Concise review: stem cell-based approaches to red blood cell production for transfusion

scientific article published on 20 December 2013

Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system.

scientific article published on 10 March 2018

Culture of human embryonic stem cells on human and mouse feeder cells

scientific article published on January 2006

Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells

scientific article published on 7 July 2005

Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells

scientific article

Detection of dual-gene expression in arteries using an optical imaging method

scientific article published in November 2004

Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer

scientific article

Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality

scientific article published on 13 January 2014

Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors

scientific article

Efficient and allele-specific genome editing of disease loci in human iPSCs

scientific article

Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013

scientific article published on 17 October 2013

Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines

scientific article

Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions

scientific article

Efficient generation of megakaryocytes from human induced pluripotent stem cells using food and drug administration-approved pharmacological reagents

scientific article

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

scientific article

Electrophysiological properties of pluripotent human and mouse embryonic stem cells

scientific article published on 9 August 2005

Erratum to: Questions about NgAgo

scientific article published on 2 December 2016

Ethics: China already has clear stem-cell guidelines

scientific article published in Nature

Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing

scientific article published on January 2013

Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors

scientific article published on 03 September 2013

FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells

scientific article published on April 2007

Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro

scientific article published on July 2004

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

scientific article published on 18 June 2009

Generation and homing of iPSC-derived hematopoietic cells in vivo

scientific article

Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells

scientific article published on 10 October 2013

Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene

scientific article published on 11 December 2016

Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression

scientific article published on 18 October 2012

Genome Editing in Human Pluripotent Stem Cells

scientific article published in April 2016

Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.

scientific article

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

scientific article published on 2 March 2006

HIF-dependent antitumorigenic effect of antioxidants in vivo

scientific article published on September 2007

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood

scientific article

High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system

scientific article published in February 2004

Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells

scientific article published on 12 March 2019

How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach.

scientific article published on September 2007

Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation

scientific article published on 3 November 2017

Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture

scientific article published on January 2003

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

scientific article

Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts

scientific article

In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells

scholarly article

In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC).

scientific article published on 18 June 2008

In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals ⬇️

scientific article published on April 10, 2003

Induced pluripotent stem cell-derived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements

scientific article published on January 2013

Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer

scientific article published on 7 December 2006

Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions

scientific article

Integration-free erythroblast-derived human induced pluripotent stem cells (iPSCs) from an individual with Ataxia-Telangiectasia (A-T).

scientific article published on 5 August 2016

Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis

scientific article

Isolation and Characterization of Extracellular Vesicles in Stem Cell-Related Studies

Lentiviral gene transduction of mouse and human stem cells

scientific article published in January 2008

Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells

scientific article

Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells.

scientific article published in July 2003

Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression

scientific article

Molecular imaging and stem cell research.

scientific article published on April 2011

More new lines of human parthenogenetic embryonic stem cells

scientific article published on February 2008

Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment

scientific article published on May 2008

Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting

scientific article

PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor

scientific article published on September 2006

Potential of human induced pluripotent stem cells derived from blood and other postnatal cell types

scientific article published on July 2010

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

scientific article

Promise and challenges of human iPSC-based hematologic disease modeling and treatment

scientific article published on 23 May 2012

Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions

scientific article published on 9 January 2007

RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells

scientific article published on 31 January 2013

Radiofrequency-enhanced vascular gene transduction and expression for intravascular MR imaging-guided therapy: feasibility study in pigs

scientific article

Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells

scientific article

Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells

scientific article published on June 2013

Robust reprogramming of Ataxia-Telangiectasia patient and carrier erythroid cells to induced pluripotent stem cells

scientific article published on 12 August 2016

Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions

scientific article published on 9 August 2013

Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix

scientific article published on 15 July 2013

Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models

scientific article

Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease ⬇️

scientific article published on 31 August 2011

Stem cells shine in Shanghai

scientific article published in January 2008

Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis

scientific article published in February 2014

Synaptic dysregulation in a human iPS cell model of mental disorders

scientific article published on 17 August 2014

TEL-AML1, expressed from t(12;21) in human acute lymphocytic leukemia, induces acute leukemia in mice.

scientific article published on July 2002

Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects

scientific article

Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells

scientific article

The dazzle in germ cell differentiation

scientific article

The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells

scientific article

The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria

scientific article published on 2 February 2012

Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins

scientific article published on April 2008

Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs

scientific article

Whole-genome sequencing identifies genetic variances in culture-expanded human mesenchymal stem cells

scientific article published on 26 June 2014

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