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List of works by Peter J. Barnes

5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene

scientific article

5-Hydroxytryptamine facilitates cholinergic bronchoconstriction in human and guinea pig airways ⬇️

scientific article published on July 1, 1995

8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy.

scientific article published in October 2003

: a new multidisciplinary journal for a new age (http://respiratory-research.com)

scientific article

A European Respiratory Society technical standard: exhaled biomarkers in lung disease.

scientific article

A Randomized Pragmatic Trial of Changing to and Stepping Down Fluticasone/Formoterol in Asthma

scientific article published on 25 March 2017

A breath of hot air?

scientific article

A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle

scientific article published on June 1, 1992

A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model

scientific article published on 01 March 2014

A fluorescent analogue of propranolol does not label beta adrenoceptor sites ⬇️

scientific article published on 01 January 1980

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

scientific article

A multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthma

scientific article published on June 2006

A novel approach to partition central and peripheral airway nitric oxide.

scientific article published in January 2014

A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: Upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist

scientific article published on 06 January 2006

A novel flow cytometric-based method to measure kinase inhibition in sputum from COPD subjects

scientific article published on 22 June 2016

A novel inhaled phosphodiesterase 4 inhibitor (CHF6001) reduces the allergen challenge response in asthmatic patients.

scientific article published on 29 June 2016

A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition.

scientific article

A novel macrolide/fluoroketolide, solithromycin (CEM-101), reverses corticosteroid insensitivity via phosphoinositide 3-kinase pathway inhibition

scientific article published on July 2013

A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.

scientific article

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

scientific article published on 17 April 2009

A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma

scientific article published on 08 January 2009

A role for M2 and M3 muscarinic receptors in the contraction of rat and human small airways

scientific article published on 08 February 2013

A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics

scientific article published on 8 May 2003

A simple and effective evidence-based approach to asthma management: ICS-formoterol reliever therapy

scholarly article

A system for the production and delivery of monodisperse salbutamol aerosols to the lungs

scientific article published in March 2003

Accelerated ageing of the lung in COPD: new concepts.

scientific article

Acidic mammalian chitinase--a potential target for asthma therapy

scientific article published in October 2004

Activation of NF-kappaB transcription factor in asthma death

scientific article published in March 2009

Activation of alpha-adrenergic response in tracheal smooth muscle: a postreceptor mechanism ⬇️

scientific article published on 01 June 1983

Activation of guinea pig eosinophil respiratory burst by leukotriene B4: role of protein kinase C

scientific article published on January 1, 1992

Activation of guinea pig pulmonary adenylate cyclase by prostacyclin ⬇️

scientific article published on October 31, 1980

Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers.

scientific article

Adenosine 5'-triphosphate's role in bradycardia and syncope associated with pulmonary embolism

scientific article published on 28 July 2018

Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89.

scientific article published on 27 January 2004

Air pollutionand asthma: molecular mechanisms ⬇️

scientific article published on June 1, 1995

Airway responsiveness and inflammation in adolescent elite swimmers

scientific article published on 12 June 2008

Albuterol Does Not Antagonize the Inhibitory Effect of Dexamethasone on Monocyte Cytokine Release ⬇️

scientific article published on 01 March 1998

Allergen Responses Modified by a GATA3 DNAzyme.

scientific article

Allergen-induced Early and Late Asthmatic Responses Are Not Affected by Inhibition of Endogenous Nitric Oxide ⬇️

scientific article published on 01 July 1998

Alpha-adrenoceptor binding in guinea-pig lung using [3H]-prazosin [proceedings] ⬇️

scientific article published on January 1, 1980

Alpha1-adrenergic receptors in guinea pig myocardium: Identification by binding of a new radioligand, (3H)-prazosin ⬇️

scientific article published on September 12, 1979

Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease.

scientific article published in December 2005

Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases

scientific article published in October 2002

An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease

scientific article published on April 2015

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

scientific article published on April 2015

Analysis of exhaled breath condensate for monitoring airway inflammation

scientific article

Analysis of expired air for oxidation products

scientific article

Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms.

scientific article

Anticholinergic Bronchodilators

As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

scientific article published in May 2018

Assessment of reproducibility of exhaled hydrogen peroxide concentration and the effect of breathing pattern in healthy subjects

scientific article

Asthma

scientific article published on 09 October 2012

Asthma mechanisms, determinants of severity and treatment: the role of nedocromil sodium Report of a workshop held in Whistler, British Columbia, Canada, 18–19 May 1995 ⬇️

scientific article published on August 1, 1995

Asthma-COPD Overlap

scientific article published on 06 January 2016

Asthma. New therapeutic approaches ⬇️

scientific article published on January 1, 1992

Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma

scientific article published in March 2002

Attenuation of tachykinin‐induced airflow obstruction and microvascular leakage in immature airways ⬇️

scientific article published on January 1, 1993

Autonomic Regulation of the Airways ⬇️

scientific article published on January 1, 1984

Autoradiographic localisation of β-adrenoceptors in human lung ⬇️

scientific article published on 01 August 1984

Autoradiographic localization of autonomic receptors in airway smooth muscle. Marked differences between large and small airways

scientific article published on 01 June 1983

Autoradiographic visualization of bradykinin receptors in human and guinea pig lung ⬇️

scientific article published on February 26, 1991

BET proteins are a key component of immunoglobulin gene expression.

scientific article

Bacterial load and defective monocyte-derived macrophage bacterial phagocytosis in biomass smoke-related COPD

scientific article published on 28 February 2019

Barnes and Adcock reply

Barriers to new drug development in respiratory disease

scientific article published in May 2015

Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro ⬇️

scientific article published on 01 March 1993

Beta-adrenergic receptors and their regulation ⬇️

scientific article published on September 1, 1995

Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease

scientific article published on 29 October 2019

Biochemical Basis of Asthma Therapy ⬇️

scientific article published on July 28, 2011

Biomarkers of some pulmonary diseases in exhaled breath

scientific article

Bleomycin-induced lung injury in rats selectively abolishes hypoxic pulmonary vasoconstriction: evidence against a role for platelet-activating factor

scientific article published on 01 March 1992

Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion ⬇️

scientific article published on April 1, 1990

Bombesin stimulates human nasal mucous and serous cell secretion in vivo ⬇️

scientific article published on 01 January 1992

Bradykinin and asthma ⬇️

scientific article published on November 1, 1992

Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells

scientific article

Breaking down barriers to lung health.

scientific article published in September 2014

Breathomics for Assessing the Effects of Treatment and Withdrawal With Inhaled Beclomethasone/Formoterol in Patients With COPD.

scientific article published on 17 April 2018

Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression

scientific article

Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?

scientific article published on 13 April 2015

Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten

scientific article (publication date: November 1992)

Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression.

scientific article

Bronchial mucosal inflammation and illness severity in response to experimental rhinovirus infection in COPD

scientific article published on 10 April 2020

Bronchoabsorption; a novel bronchoscopic technique to improve biomarker sampling of the airway.

scientific article

Bronchoconstriction and airway microvascular leakage in guinea pigs sensitized with trimellitic anhydride

scientific article published on November 1, 1992

Budesonide facilitates weaning from mechanical ventilation in difficult-to-wean very severe COPD patients: Association with inflammatory mediators and cells.

scientific article published on 31 October 2017

Burden and pathogenesis of chronic obstructive pulmonary disease

scientific article published on September 2009

CCL11 as a potential diagnostic marker for asthma?

scientific article published on 13 May 2014

COPD and Asthma: Effects Beyond the Respiratory System

scientific article

COPD as a disease of accelerated lung aging

scientific article published on January 2009

COUNTERPOINT: Will New Anti-eosinophilic Drugs Be Useful in Asthma Management? No.

scientific article

CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

scientific article published on 09 October 2007

Calcium-channel blockers and asthma ⬇️

scientific article published on July 1, 1983

Can We Define Asthma-COPD Overlap (ACO) by Biomarkers?

scientific article published on 01 January 2019

Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea ⬇️

scientific article published on December 1, 1990

Capsazepine as a selective antagonist of capsaicin-induced activation of C-fibres in guinea-pig bronchi

scientific article published on May 14, 1992

Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases

scientific article published on 01 September 2019

Cellular and molecular mechanisms of asthma and COPD.

scientific article published on July 2017

Cellular and molecular mechanisms of chronic obstructive pulmonary disease

scientific article published on 12 December 2013

Cellular endotoxin desensitization in patients with severe chronic heart failure

scientific article

Characterization of beta adrenoceptor subtypes in canine airway smooth muscle by radioligand binding and physiological responses ⬇️

scientific article published on 01 May 1983

Characterization of eosinophil cell activation by peptides. Differential effects of substance P, melittin, and FMET-Leu-Phe ⬇️

scientific article published on October 15, 1990

Characterization of guinea pig pulmonary neurokinin type 1 receptors using a novel antagonist ligand, [3H]FK888 ⬇️

scientific article published on 01 September 1993

Characterization of phosphodiesterase 4 in guinea‐pig macrophages: multiple activities, association states and sensitivity to selective inhibitors ⬇️

scientific article published on May 1, 1998

Characterization of the generation of radiolabeled monodisperse albuterol particles using the spinning-top aerosol generator.

scientific article

Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide‐induced tumour necrosis factor‐α generation ⬇️

scientific article published on September 1, 1997

Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease.

scientific article published on 30 August 2006

Children must be protected from the tobacco industry's marketing tactics.

scientific article published on 9 December 2013

Chronic Obstructive Pulmonary Disease and Lung Cancer: A Lethal Association ⬇️

scientific article published on October 15, 2011

Chronic cough and Holmes-Adie syndrome

scientific article published on 01 January 2007

Chronic heart failure in the guinea pig increases cardiac α1- and β-adrenoceptors ⬇️

scientific article published on October 3, 1980

Chronic hypoxia impairs soluble guanylyl cyclase-mediated pulmonary arterial relaxation in the rat

scientific article published on September 1, 1992

Chronic idiopathic cough: a discrete clinical entity?

scientific article published in May 2005

Chronic obstructive pulmonary disease

scientific article published on 12 December 2013

Chronic obstructive pulmonary disease

scientific article published on 03 December 2015

Chronic obstructive pulmonary disease

scholarly article by Peter J. Barnes published 1 July 2000 in The New England Journal of Medicine

Chronic obstructive pulmonary disease and lung cancer: new molecular insights

scientific article published on 24 March 2011

Chronic obstructive pulmonary disease: important advances.

scientific article

Chronic obstructive pulmonary disease: molecular and cellularmechanisms ⬇️

scientific article published on October 1, 2003

Chronic obstructive pulmonary disease: new opportunities for drug development ⬇️

scientific article published on 01 October 1998

Cigarette smoke-induced airway goblet cell secretion: dose-dependent differential nerve activation

scientific article published on 01 August 1992

Circadian Variation in Adrenergic Responses in Asthmatic Subjects ⬇️

scientific article published on 01 April 1982

Circulating autoantibodies to recombinant lipocortin-1 in asthma ⬇️

scientific article published on March 1, 1991

Circulating catecholamines in exercise and hyperventilation induced asthma ⬇️

scientific article published on June 1, 1981

Club cells, their secretory protein, and COPD

scientific article published on 01 June 2015

Comparison of Salmeterol and Albuterol-induced Bronchoprotection Against Adenosine Monophosphate and Histamine in Mild Asthma ⬇️

scientific article published on 01 December 1997

Comparison of Symbicort® versus Pulmicort® on steroid pharmacodynamic markers in asthma patients

scientific article

Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function

scientific article published on 17 September 2018

Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease

scientific article published on 01 March 2010

Comparison of the effects of salmeterol and formoterol in patients with severe asthma

scientific article

Con: Genome-Wide Association Studies Have Not Been Useful in Understanding Asthma ⬇️

scientific article published on September 15, 2011

Contrasting effects of ATP and adenosine on capsaicin challenge in asthmatic patients.

scientific article

Contrasting effects of prostaglandins E2 and F2 alpha on sensitivity of the human cough reflex ⬇️

scientific article published on August 1, 1992

Contributors

Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping

scientific article published on 27 December 2011

Correction: Suppression of GATA-3 Nuclear Import and Phosphorylation: A Novel Mechanism of Corticosteroid Action in Allergic Disease

scientific article published on 07 September 2018

Correlation between eicosanoids in bronchoalveolar lavage fluid and in exhaled breath condensate

scientific article published on January 2011

Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma ⬇️

scientific article published on February 1, 1998

Correlation of exhaled breath temperature with bronchial blood flow in asthma

scientific article

Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD.

scientific article published on 17 February 2016

Corticosteroid plus β2-agonist in a single inhaler as reliever therapy in intermittent and mild asthma: a proof-of-concept systematic review and meta-analysis

scientific article published on 6 December 2017

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

scientific article published on February 2004

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease ⬇️

scientific article published on January 26, 2013

Current Controversies in Chronic Obstructive Pulmonary Disease. A Report from the Global Initiative for Chronic Obstructive Lung Disease Scientific Committee

scientific article published on 01 January 2019

Current issues for establishing inhaled corticosteroids as the antiinflammatory agents of choice in asthma ⬇️

scientific article published on April 1, 1998

Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease

article

Cytokine-directed therapies for the treatment of chronic airway diseases ⬇️

scientific article published on December 1, 2003

Decreased Serum Sirtuin-1 in COPD.

scientific article

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

scientific article

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

scientific article

Decreased indoleamine 2,3-dioxygenase activity and IL-10/IL-17A ratio in patients with COPD.

scientific article published on 19 December 2012

Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension ⬇️

scientific article published on December 1, 1997

Decreased percentage of CD4(+)Foxp3(+)TGF-β(+) and increased percentage of CD4(+)IL-17(+) cells in bronchoalveolar lavage of asthmatics

scientific article

Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD.

scientific article

Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7

scientific article published on 15 December 2011

Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

scientific article published on 10 October 2019

Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients

scientific article

Defective phagocytosis in airways disease

scientific article published on April 2012

Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma.

scientific article published on 25 November 2015

Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma

scientific article (publication date: 2011)

Demonstration of α1-adrenoceptors in guinea pig lung using 3H-prazosin ⬇️

scientific article published on October 1, 1979

Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients

scientific article

Development of New Drugs for COPD ⬇️

scientific article published on January 1, 2013

Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs ⬇️

scientific article published on June 1, 1992

Diagnostic performance of an electronic nose, fractional exhaled nitric oxide, and lung function testing in asthma

scientific article published on 15 January 2010

Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage

scientific article published on 5 October 2007

Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.

scientific article

Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release.

scientific article

Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity

scientific article published on 01 May 2007

Differential inhibitory effects of opioids on cigarette smoke, capsaicin and electrically-induced goblet cell secretion in guinea-pig trachea ⬇️

scientific article published on February 1, 1992

Difficult asthma: Authors' reply.

scientific article published in October 1989

Direct Inhibitory Effect of the Phosphodiesterase-4 Inhibitor, Roflumilast, on Neutrophil Migration in COPD

scientific article published on 01 April 2019

Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.

scientific article

Do inhaled corticosteroid/long-acting beta2-agonist fixed combinations provide superior clinical benefits compared with separate inhalers? A literature reappraisal

scientific article published on March 2012

Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and COPD Patients.

scientific article published on 28 July 2017

Dual mechanism of action of T2 inhibitor therapies in virally induced exacerbations of asthma: evidence for a beneficial counter-regulation

scientific article published on 04 July 2019

Duplicate publication

scientific article published on 01 August 2002

ERS/ATS workshop report on respiratory health effects of household air pollution.

scientific article

Editorial: the Journal of COPD--new directions in disease understanding and management

scientific article published in April 2004

Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells

scientific article published on 19 June 2015

Effect of Regular Salmeterol Treatment on Albuterol-induced Bronchoprotection in Mild Asthma ⬇️

scientific article published on 01 September 1997

Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Effect of Thiazide Diuretics against Neurally Mediated Contraction of Guinea Pig Airways: Contribution of Carbonic Anhydrase

scientific article published on October 1, 1993

Effect of a nitric oxide synthase inhibitor and a glucocorticosteroid on exhaled nitric oxide ⬇️

scientific article published on 01 September 1995

Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers

scientific article

Effect of an inhaled glucocorticosteroid on mast cell and smooth muscle beta 2 adrenergic tolerance in mild asthma ⬇️

scientific article published on February 1, 1998

Effect of arginine on mucociliary function in primary ciliary dyskinesia ⬇️

scientific article published on 01 August 1998

Effect of beta2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A.

scientific article published on 27 June 2008

Effect of bradykinin on airway function

scientific article published on January 1, 1992

Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma ⬇️

scientific article published on June 1, 1998

Effect of frusemide on the induction and potentiation of cough induced by prostaglandin F2 alpha ⬇️

scientific article published on May 1, 1992

Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects ⬇️

scientific article published on March 1, 1998

Effect of inhaled corticosteroids on bones and growth ⬇️

scientific article published on 01 May 1998

Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects ⬇️

scientific article published on July 1, 1998

Effect of maturation on histamine-induced airflow obstruction and airway microvascular leakage in guinea pig airways

scientific article published on April 29, 1992

Effect of montelukast on exhaled leukotrienes and quality of life in asthmatic patients

scientific article published in October 2005

Effect of short- and long-acting inhaled beta2-agonists on exhaled nitric oxide in asthmatic patients ⬇️

scientific article published on 01 July 1997

Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease.

scientific article

Effects of Aerosolized Adenosine 5'-Triphosphate in Smokers and Patients With COPD.

scientific article published in August 2015

Effects of a Potent Platelet-activating Factor Antagonist, SR27417A, on Allergen-induced Asthmatic Responses ⬇️

scientific article published on 01 July 1997

Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma

scientific article published in August 2006

Effects of aerosolised substance P on lung resistance in guinea-pigs: a comparison between inhibition of neutral endopeptidase and angiotensin-converting enzyme ⬇️

scientific article published on May 1, 1990

Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma

scientific article published in October 2005

Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients

scientific article published on 21 August 2008

Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis.

scientific article published on August 2017

Effects of bronchodilator particle size in asthmatic patients using monodisperse aerosols

scientific article published in August 2003

Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway C-fibres and vagus nerve from the guinea-pig ⬇️

scientific article published on August 1, 1995

Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease

scientific article

Effects of inhaled corticosteroids on exhaled leukotrienes and prostanoids in asthmatic children

scientific article published in October 2004

Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma

scientific article

Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea‐pigs in vivo ⬇️

scientific article published on March 1, 1993

Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease.

scientific article

Efficacy and safety profile of xanthines in COPD: a network meta-analysis

scientific article published on 02 May 2018

Efficacy of inhaled corticosteroids in asthma☆☆☆★ ⬇️

scientific article published on October 1, 1998

Elevated CXCL-8 expression in bronchoalveolar lavage correlates with disease severity in patients with acute respiratory distress syndrome resulting from tuberculosis.

scientific article

Endogenous nitric oxide modulates adrenergic neural vasoconstriction in guinea-pig pulmonary artery ⬇️

scientific article published on October 1, 1991

Endogenous tachykinins facilitate transmission through parasympathetic ganglia in guinea‐pig trachea ⬇️

scientific article published on July 1, 1993

Endogenous vasoactive intestinal peptide and nitric oxide modulate cholinergic neurotransmission in guinea-pig trachea ⬇️

scientific article published on January 26, 1993

Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery ⬇️

scientific article published on February 1, 1992

Endotoxin and steroid effects on nitric oxide synthase mRNA expression in rat lung and other tissues ⬇️

scientific article published on May 1, 1994

Enhanced monocyte migration to CXCR3 and CCR5 chemokines in COPD

scientific article published on 01 April 2016

Enhanced noradrenaline response in cardiomyopathic hamsters: possible relation to changes in adrenoceptors studied by radioligand binding ⬇️

scientific article published on 01 May 1981

Eotaxin Receptor (CCR3) Antagonism in Asthma and Allergic Disease ⬇️

scientific article published on June 1, 2002

Epigenetics and chromatin remodeling play a role in lung disease

scientific article

Erratum to "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary" [Arch Bronconeumol. 2017;53:128-49].

scientific article

Erratum to “Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness” [Eur. J. Pharmacol. 452 (2002) 123–133]

scholarly article published in European Journal of Pharmacology

Evaluation of Individuals at Risk for COPD: Beyond the Scope of the Global Initiative for Chronic Obstructive Lung Disease

scientific article published on 28 June 2016

Evaluation of a breath actuated pressurized aerosol

scientific article published on 01 January 1976

Evaluation of systemic absorption and bronchodilator effect of glycopyrronium bromide delivered by nebulizer or a dry powder inhaler in subjects with chronic obstructive pulmonary disease

scientific article published on 28 June 2019

Evidence for post-transcriptional regulation of interleukin-5 by dexamethasone

scientific article published in August 2003

Evidence for prejunctional muscarinic autoreceptors in human and guinea pig trachea ⬇️

scientific article published on 01 September 1995

Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea ⬇️

scientific article published on March 1, 1995

Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis

scientific article published on 30 June 2008

Exhaled 8-isoprostane in childhood asthma

scientific article

Exhaled Nitric Oxide in Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on 01 March 1998

Exhaled and nasal nitric oxide is increased in laboratory animal allergy ⬇️

scientific article published on 01 July 1998

Exhaled biomarkers

scientific article published on November 2006

Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study

scientific article

Exhaled carbon monoxide in asthmatics: a meta-analysis

scientific article

Exhaled carbon monoxide in patients with lower respiratory tract infection ⬇️

scientific article published on 01 December 2001

Exhaled leukotrienes and prostaglandins in asthma

scientific article published in April 2002

Exhaled nitric oxide and hydrogen peroxide concentrations in asthmatic smokers

scientific article published in September 2004

Exhaled nitric oxide comes of age

scientific article published on 01 December 2012

Expression and Release of Interleukin-8 by Human Airway Smooth Muscle Cells: Inhibition by Th-2 Cytokines and Corticosteroids ⬇️

scientific article published on 01 January 1998

Expression and activity of histone deacetylases in human asthmatic airways

scientific article published in August 2002

Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells

scientific article

Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma

scientific article published on 25 September 2006

Expression of transient receptor potential C6 channels in human lung macrophages.

scientific article published on 20 October 2009

Extracellular Adenosine 5'-Triphosphate in Obstructive Airway Diseases

scientific article

Ezrin, a Membrane Cytoskeleton Cross Linker Protein, as a Marker of Epithelial Damage in Asthma

scientific article published on 01 February 2019

Faster rise of exhaled breath temperature in asthma: a novel marker of airway inflammation?

scientific article published in January 2002

Formoterol attenuates neutrophilic airway inflammation in asthma

scientific article published in October 2005

Future Advances in COPD Therapy ⬇️

scientific article published on January 1, 2001

Future directions for the ERS: presidential plans.

scientific article published in October 2013

Future drug therapy for asthma ⬇️

scientific article published on January 1, 1991

GOLD 2017: A New Report

scientific article published on 01 February 2017

Generating monodisperse pharmacological aerosols using the spinning-top aerosol generator

scientific article published in January 2006

Giants in Chest Medicine: Leonardo M. Fabbri, MD.

scientific article

Giants in chest medicine: Margaret Turner-Warwick, DBE, DM, PhD.

scientific article published in September 2014

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

scientific article

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary

scientific article published on 27 January 2017

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

scientific article published on 5 March 2017

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

scientific article published on 30 January 2017

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019

scientific article published on 18 May 2019

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

scientific article

Glottal Aperture and Buccal Airflow Leaks Critically Affect Forced Oscillometry Measurements.

scientific article

Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0.

scientific article published on 3 October 2003

Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy.

scientific article

Glucocorticoid resistance in inflammatory diseases.

scientific article published on May 2009

Glucocorticoids

scientific article

Glucocorticoids Preferentially Increase Fetal Alveolar β-Adrenoreceptors: Autoradiographic Evidence

scientific article published on 01 November 1984

Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases

scientific article

Glucocorticoids: effects on gene transcription

scientific article

Glucocorticosteroids.

scientific article published on 28 October 2016

Glucocorticosteroids: current and future directions ⬇️

scientific article published on May 1, 2011

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

scientific article

Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma

scientific article

Haplotype associated with low interleukin-10 production in patients with severe asthma ⬇️

scientific article published on July 11, 1998

Hepatocyte growth factor deficiency in COPD: a mechanism of emphysema and small airway fibrosis?

scientific article published on 01 November 2014

Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model

scientific article published on 21 September 2020

High concentrations of B-adrenergic agonists inhibit DNA binding of glucocorticoids in human lung in vitro ⬇️

scientific article published on May 1, 1995

High levels of interleukin-6 in the exhaled breath condensate of patients with COPD.

scientific article published in December 2003

Histamine increases lung permeability by an H2-receptor mechanism ⬇️

scientific article published on August 18, 1984

Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

scientific article published on 15 April 2004

Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression

scientific article

Histone deacetylation: an important mechanism in inflammatory lung diseases

scientific article published on December 2005

How do corticosteroids work in asthma?

scientific article

Human Lung Adrenoreceptors Studied by Radioligand Binding ⬇️

scientific article published on 01 June 1980

Hydrogen peroxide in exhaled breath condensate in patients with asthma: a promising biomarker?

scientific article published on 24 March 2011

Hyperventilation-induced asthma: evidence for two mechanisms ⬇️

scientific article published on September 1, 1982

Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription.

scientific article published on 30 October 2009

ICAM-1 expression is highly NF-kappaB-dependent in A549 cells. No role for ERK and p38 MAPK.

scientific article published on February 2004

ICS and COPD: time to clear the air.

scientific article published on 3 August 2009

IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter

scientific article published on November 2006

IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase.

scientific article

IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD

scientific article published in 2022

Identification of Novel Therapeutic Targets in COPD.

scientific article

Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease

scientific article published on 28 October 2013

Identifying Molecular Targets for New Drug Development for Chronic Obstructive Pulmonary Disease: What Does the Future Hold?

scientific article published on 03 August 2015

Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy

scientific article published on 28 July 2011

Immunological Features of Chronic Obstructive Pulmonary Disease (COPD) Induced by Indoor Pollution and Cigarette Smoke

scientific article

Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD

scientific article published on 13 February 2014

Impaired Dual-Specificity Protein Phosphatase DUSP4 Reduces Corticosteroid Sensitivity.

scientific article published on 10 March 2017

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages

scientific article published on 30 May 2017

Impaired Stimulus-Evoked Mucus Secretion in Cystic Fibrosis Bronchi ⬇️

scientific article published on January 1, 1993

Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease

scientific article

Impaired macrophage phagocytosis of bacteria in severe asthma.

scientific article

Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity

scientific article published on 9 August 2013

Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients

scientific article published in October 2002

Increased corticosteroid sensitivity by a long acting β2 agonist formoterol via β2 adrenoceptor independent protein phosphatase 2A activation

scientific article

Increased exhaled 8-isoprostane in childhood asthma

scientific article

Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma

scientific article (publication date: August 2002)

Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung.

scientific article published in February 2002

Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid ⬇️

scientific article published on August 1, 1998

Increased interleukin-10 and macrophage inflammatoryprotein-1α release from blood monocytes ex vivo duringlate-phase response to allergen in asthma.

scientific article

Increased interleukin-4 and decreased interferon-gamma in exhaled breath condensate of children with asthma

scientific article published in May 2002

Increased leukotrienes in exhaled breath condensate in childhood asthma

scientific article published on 5 September 2002

Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease.

scientific article published on 5 April 2017

Increased p21CIP1/WAF1and B Cell Lymphoma Leukemia-xLExpression and Reduced Apoptosis in Alveolar Macrophages from Smokers

scientific article published on 01 September 2002

Increased pulmonary α-adrenergic and reduced β-adrenergic receptors in experimental asthma ⬇️

scientific article published on June 19, 1980

Increased sensitivity of the cough reflex in progressive systemic sclerosis patients with interstitial lung disease ⬇️

scientific article published on March 1, 1998

Inflammatory endotypes in COPD

scientific article published on 31 March 2019

Inflammatory markers: exhaled nitric oxide and carbon monoxide during the ovarian cycle

scientific article published in April 2012

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease.

scientific article published on 27 May 2016

Inflammatory response to sputum induction measured by exhaled markers

scientific article published in July 2005

Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease

scientific article

Inhaled Aerosol Distribution in Human Airways: A Scintigraphy-Guided Study in a 3D Printed Model.

scientific article published on 23 June 2016

Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.

scientific article published in May 2018

Inhaled Corticosteroids

scientific article

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

scientific article

Inhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD.

scientific article published on 23 September 2013

Inhaled prazosin in asthma ⬇️

scientific article published on May 1, 1981

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT)

scientific article

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT).

scientific article published on 26 May 2016

Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist.

scientific article published on 16 December 2013

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice

scientific article published on 22 January 2009

Inhibition of cholinergic neurotransmission in guinea pig trachea by NS1619, a putative activator of large-conductance, calcium-activated potassium channels ⬇️

scientific article published on August 1, 1998

Inhibition of cholinergic neurotransmission in human airways by opioids ⬇️

scientific article published on March 1, 1992

Inhibition of macrophage inflammatory protein-1 alpha expression by IL-10. Differential sensitivities in human blood monocytes and alveolar macrophages ⬇️

scientific article published on November 1, 1995

Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96,345, a new non-peptide NK1 receptor antagonist ⬇️

scientific article published on February 1, 1992

Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding

scientific article published on 19 February 2004

Inhibitory cytokines in asthma ⬇️

scientific article published on October 1, 1998

Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD.

scientific article

Insights into oxidative stress: the isoprostanes

scientific article published on January 2007

Integrated care pathways for airway diseases (AIRWAYS-ICPs).

scientific article published on 12 June 2014

Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis

scientific article

Interleukin-10 modulates pulmonary neutrophilic inflammation induced by cigarette smoke exposure

scientific article

Interleukin-5 Induces CD34+Eosinophil Progenitor Mobilization and Eosinophil CCR3 Expression in Asthma ⬇️

scientific article published on October 15, 2001

Interview With Peter J Barnes ⬇️

scientific article published on August 1, 2013

Interview with Peter Barnes ⬇️

scientific article published on October 1, 2011

Introducing a new series: Giants in chest medicine

scientific article published on 01 October 2013

Involvement of IL-13 in tobacco smoke-induced changes in the structure and function of rat intrapulmonary airways

scientific article published on 25 September 2009

Involvement of inflammatory mediators in the airway responses to trimellitic anhydride in sensitized guinea-pigs ⬇️

scientific article published on August 1, 1992

Isoprostanes: markers and mediators of oxidative stress

scientific article

Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism.

scientific article published on 30 March 2017

K+ channel activator inhibition of neurogenic goblet cell secretion in guinea pig trachea

scientific article published on May 14, 1992

Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.

scientific article published on July 2016

Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury

scientific article

Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle ⬇️

scientific article published on May 1, 1991

Leukotriene B4 activates the NADPH oxidase in eosinophils by a pertussis toxin-sensitive mechanism that is largely independent of arachidonic acid mobilization ⬇️

scientific article published on 01 May 1998

Liquid chromatography/mass spectrometry analysis of exhaled leukotriene B4 in asthmatic children

scientific article

Localization and function of airway autonomic receptors

scientific article published on 01 January 1984

Localization of β-adrenoreceptors in mammalian lung by light microscopic autoradiography ⬇️

scientific article published on September 30, 1982

Localization of β2-adrenoceptor messenger RNA in human and rat lung using in situ hybridization: correlation with receptor autoradiography ⬇️

scientific article published on February 25, 1991

Long-acting beta 2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified?

scientific article

Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells

scientific article published on 2 September 2011

Looking for Airways Periostin in Severe Asthma: Could It Be Useful for Clustering Type 2 Endotype?

scientific article published on 15 October 2018

Loop diuretics and asthma

scientific article published on January 1, 1992

Loss of Control of Asthma Following Inhaled Corticosteroid Withdrawal Is Associated With Increased Sputum Interleukin-8 and Neutrophils

scientific article published on 05 June 2007

Low-Dose Budesonide/Formoterol Counteracts Airway Inflammation and Improves Lung Function in Chronic Obstructive Pulmonary Disease

scientific article published on 01 March 2019

Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT

scientific article published on 01 July 2019

MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients.

scientific article published in September 2009

Managing asthma in hospital: cause for concern ⬇️

scientific article published on January 1, 1991

Mapping of Adrenergic Receptors in the Trachea by Autoradiography ⬇️

scientific article published on 01 November 1983

Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids.

scientific article published in November 2002

Measurement of 8-isoprostane in exhaled breath condensate

scientific article published in January 2010

Measurement of Exhaled Hydrocarbons

scientific article published on 01 January 2001

Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma

scientific article published on 20 April 2006

Measurement of plasma histamine in asthma ⬇️

scientific article published on 01 January 1983

Mechanisms of development of multimorbidity in the elderly

scientific article

MicroRNA-570 is a novel regulator of cellular senescence and inflammaging

scientific article published on 29 August 2018

Microarray analysis of long non-coding RNAs in COPD lung tissue.

scientific article published on 27 December 2014

Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease.

scientific article

Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages

scientific article published on 18 July 2003

Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells.

scientific article published on 21 February 2003

Modulation of neural bronchoconstrictor responses in the guinea pig respiratory tract by vasoactive intestinal peptide ⬇️

scientific article published on March 1, 1991

Modulation of neurotransmission in airways

scientific article published on July 1, 1992

Molecular Mechanisms of Glucocorticoid Action in Asthma ⬇️

scientific article published on January 1, 1997

Molecular biologic aspects of chronic inflammation reaction in bronchial asthma: incentive for new therapeutic concepts?

scientific article published on 01 November 1997

Molecular biology of receptors

scientific article published on May 1, 1992

Molecular mechanisms of corticosteroid resistance.

scientific article published on August 2008

Muscarinic M2 receptor synthesis: study of receptor turnover with propylbenzilylcholine mustard ⬇️

scientific article published on August 15, 1995

NF-kB: a pivotal role in asthma and a new target for therapy

scholarly article by Peter J. Barnes & Ian M. Adcock published February 1997 in Trends in Pharmacological Sciences

NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription

scientific article published on January 2006

NHLBI workshop summaries. Neuroimmune interactions in the lung

scientific article published on May 1, 1992

NHLBI workshop summary. Platelet-activating factor: role in pulmonary injury and dysfunction and blood abnormalities

scientific article published on 01 March 1992

NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis

scientific article published in March 2012

NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis

scientific article published on 21 November 2011

Nasal contribution to exhaled nitric oxide during exhalation against resistance or during breath holding ⬇️

scientific article published on June 1, 1997

Nasal inflammation and its response to local glucocorticoid regular treatment in patients with persistent non-allergic rhinitis: a pilot study

scientific article published on 04 August 2016

Nedocromil Sodium Modulates Nonadrenergic, Noncholinergic Bronchoconstrictor Nerves in Guinea Pig AirwaysIn Vitro

scientific article published on 01 January 1991

Neural mechanisms in asthma: New developments ⬇️

scientific article published on January 1, 1997

Neurogenic Inflammation in Airways ⬇️

scientific article published on January 1, 1991

Neuropeptide Y is a vasoconstrictor in human nasal mucosa ⬇️

scientific article published on 01 November 1992

Neuropeptides in the Respiratory Tract: Part II

scientific article published on December 1, 1991

Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4.

scientific article published in April 2003

New Drugs for Asthma ⬇️

scientific article published on 09 October 2012

New Drugs for the Treatment of Allergy and Asthma

New Therapies for Asthma and Chronic Obstructive Pulmonary Disease

scientific article

New anti-inflammatory targets for chronic obstructive pulmonary disease.

scientific article published on July 2013

New drugs for exacerbations of chronic obstructive pulmonary disease

scientific article published on August 2009

New perspectives in pharmacological treatment of mild persistent asthma ⬇️

scientific article published on September 10, 2011

Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2.

scientific article published on 3 May 2009

Nitric oxide as a neurotransmitter in human airways

scientific article published on January 1, 1995

Nitric oxide as an endogenous modulator of cholinergic neurotransmission in guinea-pig airways ⬇️

scientific article published on June 6, 1991

Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans

scientific article published on January 14, 1992

Nitric oxide metabolites are not reduced in exhaled breath condensate of patients with primary ciliary dyskinesia

scientific article published in August 2003

Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease

scientific article published on 24 September 2009

Nitric oxide, nitrotyrosine, and nitric oxide modulators in asthma and chronic obstructive pulmonary disease

scientific article

Nitrosative stress in patients with asthma-chronic obstructive pulmonary disease overlap

scientific article published on 16 August 2019

Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease

scientific article published on 28 September 2005

No Evidence Electric Charge Increases Inhaled Ultrafine Particle Deposition in Human Lungs

scientific article published on 29 January 2020

Nocturnal Asthma and Changes in Circulating Epinephrine, Histamine, and Cortisol ⬇️

scientific article published on July 31, 1980

Nonadrenergic, noncholinergic airway inhibitory nerves ⬇️

scientific article published on February 1, 1992

Normal bronchial blood flow in COPD is unaffected by inhaled corticosteroids and correlates with exhaled nitric oxide

scientific article published on 01 April 2007

Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ

scientific article

Nuclear factor-kappaB does not mediate the inhibitory effects of dexamethasone on granulocyte-macrophage colony-stimulating factor expression.

scientific article published on April 2004

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.

scientific article

Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants

scientific article published on 25 October 2007

Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial.

scientific article published on 20 April 2016

Oscillating Positive Expiratory Pressure on Respiratory Resistance in Chronic Obstructive Pulmonary Disease With a Small Amount of Secretion: A Randomized Clinical Trial

scientific article

Osteoprotegerin in sputum is a potential biomarker in COPD

scientific article published on 02 December 2010

Overcoming steroid insensitivity in smoking asthmatics.

scientific article published on May 2008

Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD.

scientific article

Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells

scientific article published on 21 October 2016

Oxidative stress in COPD.

scientific article published on July 2013

Oxidative stress induces NFkB DNA binding and inducible NOS mRNA in the human epithelial cell line A549 ⬇️

scientific article published on May 1, 1994

Oxidative stress modulates theophylline effects on steroid responsiveness

scientific article published on 23 October 2008

Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease

scientific article

Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

scientific article

Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease.

scientific article published on 14 December 2009

Ozone-induced increase in exhaled 8-isoprostane in healthy subjects is resistant to inhaled budesonide

scientific article published in November 2002

Partial flow-volume curves to measure bronchodilator dos-response curves in normal humans ⬇️

scientific article published on 01 June 1981

Passive smoking impairs histone deacetylase-2 in children with severe asthma.

scientific article published on February 2014

Pathogenesis of Asthma: A Review ⬇️

scientific article published on 01 July 1983

Pathogenesis of COPD and Asthma.

scientific article published on 26 November 2016

Pathophysiology of allergic inflammation ⬇️

scientific article published on July 1, 2011

Peptide mediator effects on bronchial blood velocity and lung resistance in conscious sheep ⬇️

scientific article published on March 1, 1992

Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine

scientific article published on 2 February 2009

Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer.

scientific article published on 25 February 2015

Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices

scientific article published on 4 October 2007

Pharmacological modulation of inhaled sodium metabisulphite-induced airway microvascular leakage and bronchoconstriction in the guinea-pig ⬇️

scientific article published on October 1, 1992

Pharmacological treatment of COPD: the devil is always in the detail.

scientific article published on 19 April 2018

Phenotypic comparison between smoking and non-smoking chronic obstructive pulmonary disease

scientific article published on 12 February 2020

Phosphodiesterase expression in human epithelial cells ⬇️

scientific article published on October 1, 1998

Platelet-activating factor: a potent mediator of inflammation.

scientific article published in June 1989

Poorly perceived asthma ⬇️

scientific article published on June 1, 1992

Positional cloning of a novel gene influencing asthma from chromosome 2q14.

scientific article

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma

scientific article

Postnatal changes in beta-adrenoceptors in the lung and the effect of hypoxia induced pulmonary hypertension of the newborn.

scientific article

Postsynaptic alpha 2-adrenoceptors predominate over alpha 1-adrenoceptors in canine tracheal smooth muscle and mediate neuronal and hormonal alpha-adrenergic contraction ⬇️

scientific article published on 01 May 1983

Prazosin, an alpha1-adrenoceptor antagonist, partially inhibits exercise-induced asthma ⬇️

scientific article published on 01 December 1981

Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative

scientific article published on 11 July 2018

Probiotics in the management of lung diseases

scientific article published on 8 May 2013

Professor Neil B. Pride (1931-2016)

scientific article published on 03 January 2017

Professor Neil Pride

scientific article published on 11 January 2017

Prospects for new drugs for chronic obstructive pulmonary disease

scientific article published in September 2004

Prostaglandin E2 suppression of acetylcholine release from parasympathetic nerves innervating guinea‐pig trachea by interacting with prostanoid receptors of the EP3‐subtype ⬇️

scientific article published on March 1, 1998

Protective effect of loop diuretics, piretanide and frusemide, against sodium metabisulphite-induced bronchoconstriction in asthma ⬇️

scientific article published on 01 November 1992

Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity.

scientific article published on 24 March 2016

Pulmonary Diseases and Ageing

scientific article published on 01 January 2019

Pulmonary α-adrenoceptors: Autoradiographic localization using [3H]prazosin ⬇️

scientific article published on March 18, 1983

Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor

scientific article published on December 1, 1992

Quercetin restores corticosteroid sensitivity in cells from patients with chronic obstructive pulmonary disease

scientific article published on 11 December 2017

Questions about inhaled beta 2-adrenoceptor agonists in asthma

scientific article published on January 1, 1992

Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study

scientific article published on 10 April 2008

Rapid effects of extrafine beclomethasone dipropionate/formoterol fixed combination inhaler on airway inflammation and bronchoconstriction in asthma: a randomised controlled trial

scientific article

Rebuttal From Dr Barnes

scientific article published on 13 October 2016

Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response.

scientific article

Reduced Clearance of Fungal Spores by Chronic Obstructive Pulmonary Disease GM-CSF- and M-CSF-derived Macrophages.

scientific article published in February 2018

Reduced HDAC2 in skeletal muscle of COPD patients

scientific article

Reduced denitration activity in peripheral lung of chronic obstructive pulmonary disease.

scientific article

Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size

scientific article published on 28 September 2005

Regulation of IL-17 in chronic inflammation in the human lung

scientific article published on 01 June 2011

Regulation of NANC neural bronchoconstriction in vivo in the guinea‐pig: involvement of nitric oxide, vasoactive intestinal peptide and soluble guanylyl cyclase ⬇️

scientific article published on January 1, 1993

Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3.

scientific article published on February 2007

Regulation of Wnt4 in chronic obstructive pulmonary disease

scientific article published on 5 March 2013

Regulation of m2 Muscarinic Receptor Gene Expression by Platelet-Derived Growth Factor: Involvement of Extracellular Signal-Regulated Protein Kinases in the Down-Regulation Process ⬇️

scientific article published on 01 December 1997

Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma

scientific article published on 13 April 2006

Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease

scientific article published on 01 May 2002

Repeatability of standardised nasal nitric oxide measurements in healthy and asthmatic adults and children

scientific article

Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase δ pathway

scientific article published on 28 July 2016

Reply

Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule I B Kinase Inhibitors

article

Rescue treatment in asthma. More than as-needed bronchodilation

scientific article published on June 2009

Respiratory diseases in the world: one voice "united for lung health"

article

Response

Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists

scientific article

Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin

scientific article published on October 2015

Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma

scientific article (publication date: 2012)

Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation.

scientific article published on 18 July 2013

Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease

scientific article

Role for platelet-activating factor in asthma ⬇️

scientific article published on December 1, 1991

Role of CBP in glucocorticoid-induced gene repression ⬇️

scientific article published on 01 August 1998

Role of K+ channels in the modulation of cholinergic neural responses in guinea-pig and human airways ⬇️

scientific article published on September 1, 1992

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

scientific article published on 13 December 2017

Role of inflammatory mediators in asthma ⬇️

scientific article published on January 1, 1992

Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries ⬇️

scientific article published on November 1, 1992

Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness

scientific article published in September 2002

Role of potassium channels in bronchodilator responses in human airways

scientific article published on 01 July 1992

Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation ⬇️

scientific article published on 01 October 1998

STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects.

scientific article

Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: a randomized, double-blind, placebo-controlled trial

scientific article published on 14 April 2008

Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis

scientific article

Senescence in COPD and Its Comorbidities.

scientific article published on 9 December 2016

Senotherapy: A New Horizon for COPD Therapy

scientific article published on 10 February 2020

Sensory neuropeptides and hypoxic pulmonary vasoconstriction in the rat ⬇️

scientific article published on May 1, 1993

Severe asthma: Advances in current management and future therapy ⬇️

scientific article published on January 1, 2012

Sex Differences in Chronic Obstructive Pulmonary Disease Mechanisms

scientific article

Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD.

scientific article

Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanism

scientific article published on 24 August 2016

Small airway fibrosis in COPD

scientific article published on 06 September 2019

Smoking cessation in COPD causes a transient improvement in spirometry and decreases micronodules on high-resolution CT imaging.

scientific article

Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.

scientific article published on 20 May 2004

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

scientific article

Sputum myeloperoxidase in chronic obstructive pulmonary disease.

scientific article

Sputum plasminogen activator inhibitor-1 elevation by oxidative stress-dependent nuclear factor-κB activation in COPD.

scientific article published in August 2013

Statins as potential therapeutic drug for asthma?

scientific article

Statins enhance the effects of corticosteroids on the balance between regulatory T cells and Th17 cells.

scientific article

Steroid-resistant neutrophilic inflammation in a mouse model of an acute exacerbation of asthma

scientific article published on 12 May 2008

Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease

scientific article

Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications

scientific article published on 19 July 2019

TGF-β Signaling Pathways in Different Compartments of the Lower Airways of Patients With Stable COPD.

scientific article published on 28 December 2017

Targeting cytokines to treat asthma and chronic obstructive pulmonary disease

scientific article published on 01 July 2018

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

scientific article

Th2 cytokines and asthma: an introduction ⬇️

scientific article published on March 8, 2001

The Asthma Control Questionnaire as a clinical trial endpoint: past experience and recommendations for future use

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The Effect of Low Dose Corticosteroids and Theophylline on the Risk of Acute Exacerbations of COPD. The TASCS Randomised Controlled Trial

scientific article published on 17 December 2020

The European Respiratory Society plans its future: the 2013-2018 strategic plan

scientific article published in April 2014

The Hidden Burden of Severe Asthma: From Patient Perspective to New Opportunities for Clinicians

scientific article published on 27 July 2020

The Launch of a New COPD Journal

scientific article published on 6 May 2014

The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.

scientific article published on 11 January 2016

The Pressing Need to Redefine "COPD"

scientific article published on 01 November 2019

The acute effect of swimming on airway inflammation in adolescent elite swimmers

scientific article published on 01 February 2009

The burden of exacerbations in mild asthma: a systematic review

scientific article published on 01 July 2020

The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure.

scientific article published on 6 March 2018

The effect of body weight on distal airway function and airway inflammation.

scientific article published on 24 November 2015

The effect of sensory nerve depletion on cholinergic neurotransmission in guinea pig airways ⬇️

scientific article published on March 1, 1992

The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma

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The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma

scientific article published on 13 July 2006

The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

scientific article published on 29 June 2011

The effects of the novel SHIP1 activator AQX-1125 on allergen-induced responses in mild-to-moderate asthma.

scientific article published in September 2014

The electronic nose in respiratory medicine

scientific article published on 25 September 2012

The epithelial cell and lung cancer: Introduction ⬇️

scientific article published on December 15, 2010

The evolving algorithm of biological selection in severe asthma

scientific article published on 03 March 2020

The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease

scientific article published in 2021

The low-chloride cough response is not inhibited by a single, high dose of aspirin ⬇️

scientific article published on October 1, 1992

The management of newly identified asthma in primary care in England

scientific article published on 01 December 2002

The novel inhaled glucocorticoid receptor agonist GW870086X protects against adenosine-induced bronchoconstriction in asthma.

scientific article published on 14 March 2015

The prevalence of small airways disease in adult asthma: A systematic literature review

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The relationship between age and production of tumour necrosis factor-alpha in healthy volunteers and patients with chronic heart failure

scientific article published on 01 August 2003

The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells

scientific article published on November 2007

The role of oxidative stress in chronic obstructive pulmonary disease

scientific article published on January 2004

The third nervous system in the lung: physiology and clinical perspectives ⬇️

scientific article published on August 1, 1984

The trials and tribulations of anti-IL-5 em leader

scientific article published on 01 March 2002

Theophylline

scientific article published on 01 October 2013

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

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Theophylline.

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Theophylline: mechanism of action and use in asthma and chronic obstructive pulmonary disease

scientific article published on January 2004

Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes.

scientific article published on September 2015

Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD.

scientific article

Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma

scientific article published on October 22, 1992

Toll-like receptor 3 stimulation causes corticosteroid-refractory airway neutrophilia and hyperresponsiveness in mice.

scientific article published in July 2013

Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD.

scientific article

Triple inhalers for obstructive airways disease: will they be useful? ⬇️

scientific article published on 01 June 2011

Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects ⬇️

scientific article published on 01 July 1995

Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1.

scientific article

Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells.

scientific article published on 4 October 2002

Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer

scientific article

Update in chronic obstructive pulmonary disease 2011.

scientific article published on June 2012

Updates in Chronic Obstructive Pulmonary Disease for the Year 2014

scientific article published on 01 April 2015

Use of a fixed combination beta 2-agonist and steroid dry powder inhaler in asthma ⬇️

scientific article published on April 1, 1995

Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial

scientific article published on 10 June 2015

Using magnetic resonance imaging to quantify the inflammatory response following allergen challenge in allergic rhinitis

scientific article

VIP and asthma ⬇️

scientific article published on January 14, 1984

Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells.

scientific article

Validation of the Exhaled Breath Temperature Measure: Reference Values in Healthy Subjects.

scientific article published on 23 November 2016

Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle

Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach

scientific article published on 13 August 2020

What the Journal Would Like to Publish on Chronic Obstructive Pulmonary Disease

scientific article published on 01 July 2010

Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways ⬇️

scientific article published on September 1, 2003

p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma

scientific article

p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma

scientific article published on 14 September 2011

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