List of works - Otto Hannes Vogel

A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome.

scientific article published on 3 July 2013

Abnormal hepatocellular mitochondria in methylmalonic acidemia

scientific article published on 16 June 2014

Allelic phasing of a mouse chromosome 11 deficiency influences p53 tumorigenicity

scientific article published on 01 May 2003

Arterial spin-labeled perfusion of pediatric brain tumors.

scientific article published in August 2013

Atypical and rare variants of central neurocytomas

scientific article published on 18 October 2014

Atypical teratoid/rhabdoid tumor with ganglioglioma-like differentiation: case report and review of the literature

scientific article published on 10 September 2013

Brain abscess caused by Phaeoacremonium parasiticum in an immunocompromised patient.

scientific article published on 29 December 2010

Burden of proof in the postmortem diagnosis of mitochondrial disease: Leigh disease

scientific article published on 01 November 2004

CHD5 is a tumor suppressor at human 1p36

scientific journal article

CNS T-cell lymphoma: an under-recognized entity?

scientific article

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast

scientific journal article

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

scientific article (publication date: December 2000)

Central nervous system stem cell transplantation for children with neuronal ceroid lipofuscinosis.

scientific article published on 12 April 2013

Characterization of the integrin alpha v beta3 in arteriovenous malformations and cavernous malformations.

scientific article published on 30 May 2005

Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease.

scientific article published in October 2004

Composite pleomorphic xanthoastrocytoma-epithelioid glioneuronal tumor with BRAF V600E mutation - report of three cases

scientific article

Congenital glioblastoma multiforme: case report and review of the literature.

scientific article

Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations

scientific article

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

scientific article published on 01 October 2003

Cytogenetic analysis of 120 primary pediatric brain tumors and literature review ⬇️

scientific article published on August 1, 1997

Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study

scientific article published on 13 August 2020

Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer.

scientific article

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.

scientific article

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

scientific article published on April 2003

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

scientific article

Deletion of Ku86 causes early onset of senescence in mice

scientific article (publication date: 14 September 1999)

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma

scientific article published on 13 February 2014

Diffusion-weighted MRI: distinction of skull base chordoma from chondrosarcoma.

scientific article

Distinctive MRI features of pediatric medulloblastoma subtypes.

scientific article

Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.

scientific article

EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.

scientific article

Effects of genetic background on tumorigenesis in p53-deficient mice

scientific article published on 01 September 1995

Embryonic Lethality and Tumorigenesis Caused by Segmental Aneuploidy on Mouse Chromosome 11 ⬇️

scientific article published on November 1, 1998

Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models.

scientific article

Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.

scientific article

G1 arrest and differentiation can occur independently of Rb family function ⬇️

scientific article published on November 8, 2010

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

scientific article published on 07 February 2022

Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport.

scientific article published on 24 March 2006

Gene-protein correlation in single cells ⬇️

scientific article published on August 1, 2011

Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway

scientific article

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

scientific article

Hematopoietic cells maintain hematopoietic fates upon entering the brain.

scientific article

Highly proliferative sellar chordoma with unusually rapid recurrence.

scientific article

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

scientific article

Input-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brain

scientific journal article

Intraventricular metaplastic meningioma in a child: case report and review of the literature.

scientific article

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

scientific article

Late profound muscle weakness following heart transplantation due to Danon disease.

scientific article published on 21 November 2012

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

scientific article

Liposomal cytarabine for central nervous system embryonal tumors in children and young adults

scientific article published on 22 September 2010

Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis ⬇️

scientific article published on October 21, 2010

MRI surrogates for molecular subgroups of medulloblastoma.

scientific article published on 15 May 2014

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

scientific article (publication date: 11 July 2006)

Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance.

scientific article

Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.

scientific article

Muscle lymphocytic infiltrates in thymoma-associated myasthenia gravis are phenotypically different from those in polymyositis.

scientific article

NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs.

scientific article

NFKBIADeletion in Glioblastomas ⬇️

scientific article published on December 22, 2010

Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system

scientific article published on 01 March 1995

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.

scientific article

Novel homoplasmic mutation in the mitochondrial tRNATyr gene associated with atypical mitochondrial cytopathy presenting with focal segmental glomerulosclerosis ⬇️

scientific article published on 01 December 2003

Occult pigmented ganglioglioma in an adult male with chronic posttraumatic epilepsy.

scientific article published in May 2013

Pilocytic astrocytoma with IDH1 mutation in the cerebellum of an elderly patient.

scientific article

Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA.

scientific article published on 27 January 2015

Pituitary stalk Langerhans cell histiocytosis treated with CyberKnife radiosurgery.

scientific article published on 25 July 2012

Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis

scientific article published on 11 April 2016

Primary pediatric skull tumors.

scientific article published on January 2011

Progressive cerebral vascular degeneration with mitochondrial encephalopathy.

scientific article published in February 2008

Recessive dystrophic epidermolysis bullosa associated with mesangioproliferative glomerulonephritis and multifocal necrotizing leucoencephalopathy of the pons

scientific article published on 01 December 2004

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

scientific article

Retrosellar intracranial extracerebral glioneuronal heterotopion: case report

scientific article published on 01 September 2010

Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9

scientific article

Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure.

scientific article published on 08 May 2008

Smad5 is essential for left-right asymmetry in mice.

scientific article published in March 2000

Spinal pilocytic astrocytoma in an elderly patient.

scientific article published in November 2011

Subventricular spread of diffuse intrinsic pontine glioma

scientific article

Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.

scientific article published on 23 December 2013

Tectal pineal cyst in a 1-year-old girl.

scientific article

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

scientific article

Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.

scientific article

Vascular-type disruptive defects in fetuses with homozygous alpha-thalassemia: report of two cases and review of the literature.

scientific article

Visual genotyping of a coat color tagged p53 mutant mouse line

scientific article published on 01 July 2002

Wnt-mediated self-renewal of neural stem/progenitor cells.

scholarly article

alpha(v)beta(3) Integrin in central nervous system tumors.

scientific article published in June 2005

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

scholarly article

List of works by Otto Hannes Vogel

A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome.

Abnormal hepatocellular mitochondria in methylmalonic acidemia

Allelic phasing of a mouse chromosome 11 deficiency influences p53 tumorigenicity

Arterial spin-labeled perfusion of pediatric brain tumors.

Atypical and rare variants of central neurocytomas

Atypical teratoid/rhabdoid tumor with ganglioglioma-like differentiation: case report and review of the literature

Brain abscess caused by Phaeoacremonium parasiticum in an immunocompromised patient.

Burden of proof in the postmortem diagnosis of mitochondrial disease: Leigh disease

CHD5 is a tumor suppressor at human 1p36

CNS T-cell lymphoma: an under-recognized entity?

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

Central nervous system stem cell transplantation for children with neuronal ceroid lipofuscinosis.

Characterization of the integrin alpha v beta3 in arteriovenous malformations and cavernous malformations.

Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease.

Composite pleomorphic xanthoastrocytoma-epithelioid glioneuronal tumor with BRAF V600E mutation - report of three cases

Congenital glioblastoma multiforme: case report and review of the literature.

Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

Cytogenetic analysis of 120 primary pediatric brain tumors and literature review ⬇️

Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study

Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer.

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

Deletion of Ku86 causes early onset of senescence in mice

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma

Diffusion-weighted MRI: distinction of skull base chordoma from chondrosarcoma.

Distinctive MRI features of pediatric medulloblastoma subtypes.

Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.

EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.

Effects of genetic background on tumorigenesis in p53-deficient mice

Embryonic Lethality and Tumorigenesis Caused by Segmental Aneuploidy on Mouse Chromosome 11 ⬇️

Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models.

Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.

G1 arrest and differentiation can occur independently of Rb family function ⬇️

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport.

Gene-protein correlation in single cells ⬇️

Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Hematopoietic cells maintain hematopoietic fates upon entering the brain.

Highly proliferative sellar chordoma with unusually rapid recurrence.

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

Input-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brain

Intraventricular metaplastic meningioma in a child: case report and review of the literature.

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

Late profound muscle weakness following heart transplantation due to Danon disease.

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

Liposomal cytarabine for central nervous system embryonal tumors in children and young adults

Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis ⬇️

MRI surrogates for molecular subgroups of medulloblastoma.

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance.

Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.

Muscle lymphocytic infiltrates in thymoma-associated myasthenia gravis are phenotypically different from those in polymyositis.

NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs.

NFKBIADeletion in Glioblastomas ⬇️

Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.

Novel homoplasmic mutation in the mitochondrial tRNATyr gene associated with atypical mitochondrial cytopathy presenting with focal segmental glomerulosclerosis ⬇️

Occult pigmented ganglioglioma in an adult male with chronic posttraumatic epilepsy.

Pilocytic astrocytoma with IDH1 mutation in the cerebellum of an elderly patient.

Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA.

Pituitary stalk Langerhans cell histiocytosis treated with CyberKnife radiosurgery.

Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis

Primary pediatric skull tumors.

Progressive cerebral vascular degeneration with mitochondrial encephalopathy.

Recessive dystrophic epidermolysis bullosa associated with mesangioproliferative glomerulonephritis and multifocal necrotizing leucoencephalopathy of the pons

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

Retrosellar intracranial extracerebral glioneuronal heterotopion: case report

Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9

Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure.

Smad5 is essential for left-right asymmetry in mice.

Spinal pilocytic astrocytoma in an elderly patient.

Subventricular spread of diffuse intrinsic pontine glioma

Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.

Tectal pineal cyst in a 1-year-old girl.

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.