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List of works by Francisco Javier Otero Espinar

3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease

scientific article published on 02 December 2020

A multicentre prospective study evaluating the impact of proton-pump inhibitors omeprazole and pantoprazole on voriconazole plasma concentrations

scientific article published on 28 February 2020

Acrylic/cyclodextrin hydrogels with enhanced drug loading and sustained release capability.

scientific article published on 7 February 2006

Anticryptosporidial activity of furan derivative G1 and its inclusion complex with beta-cyclodextrin.

scientific article

Bioadhesive emulsions for control release of progesterone resistant to vaginal fluids clearance.

scientific article published in November 2014

Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery

scientific article published on 30 July 2020

Characterization of New Proteomic Biomarker Candidates in Mucopolysaccharidosis Type IVA

scientific article published on 28 December 2020

Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation.

scientific article

Chitosan and chondroitin microspheres for oral-administration controlled release of metoclopramide

scientific article published on 01 September 1999

Competitive displacement of drugs from cyclodextrin inclusion complex by polypseudorotaxane formation with poloxamer: implications in drug solubilization and delivery

scientific article published on 13 December 2011

Curcumin–Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders

scientific article published in 2021

Cyclodextrin based rotaxanes, polyrotaxanes and polypseudorotaxanes and their biomedical applications

scientific article published on January 2014

Cyclodextrin-based polysaccharidic polymers: an approach for the drug delivery.

scientific article published on January 2014

Cyclodextrin-polysaccharide-based, in situ-gelled system for ocular antifungal delivery.

scientific article published on 8 December 2014

Cyclodextrins: more than pharmaceutical excipients.

scientific article published on July 2010

Cysteamine ophthalmic hydrogel for the treatment of ocular cystinosis

scientific article

Cysteamine polysaccharide hydrogels: Study of extended ocular delivery and biopermanence time by PET imaging.

scientific article published on 17 June 2017

Development and characterization of anti-inflammatory activity of curcumin-loaded biodegradable microspheres with potential use in intestinal inflammatory disorders

scientific article published on 28 December 2016

Development, Characterization, and In Vitro Evaluation of Resveratrol-Loaded Poly-(ε-caprolactone) Microcapsules Prepared by Ultrasonic Atomization for Intra-Articular Administration

scientific article published on 28 May 2019

Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations

scientific article published on 16 March 2020

Drug loading optimization and extended drug delivery of corticoids from pHEMA based soft contact lenses hydrogels via chemical and microstructural modifications.

scientific article published on 17 April 2015

Effect of Penetration Enhancers on Drug Nail Permeability from Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers

scientific article published on 13 December 2018

Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer

scientific article published on 11 September 2018

Enzyme-Loaded Gel Core Nanostructured Lipid Carriers to Improve Treatment of Lysosomal Storage Diseases: Formulation and In Vitro Cellular Studies of Elosulfase Alfa-Loaded Systems

scientific article published on 11 October 2019

Evaluation of the in vitro ocular toxicity of the fortified antibiotic eye drops prepared at the Hospital Pharmacy Departments.

scientific article published in September 2016

Evaluation of the promoting effect of soluble cyclodextrins in drug nail penetration

scientific article published on 06 March 2018

Evaluation of the therapeutic activity of melatonin and resveratrol in Inflammatory Bowel Disease: A longitudinal PET/CT study in an animal model

scientific article published on 05 October 2019

Formulation of triamcinolone acetonide pellets suitable for coating and colon targeting

scientific article published on 01 March 1999

Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof: implications for drug delivery

scientific article published on 23 August 2011

Hydrocortisone loaded poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) nanoparticles for topical ophthalmic administration: Preparation, characterization and evaluation of ophthalmic toxicity

scientific article published on 13 July 2019

Hydrosoluble cyclodextrin/poloxamer polypseudorotaxanes at the air/water interface, in bulk solution, and in the gel state.

scientific article published in March 2009

Image analysis of the shape of granulated powder grains

scientific article published on 01 March 2004

Impact of CYP2C19 Genotype and Drug Interactions on Voriconazole Plasma Concentrations: A Spain Pharmacogenetic-Pharmacokinetic Prospective Multicenter Study

scientific article published on 01 January 2020

Improved release of triamcinolone acetonide from medicated soft contact lenses loaded with drug nanosuspensions

scientific article published on 12 April 2017

In Vitro Evaluation of the Ophthalmic Toxicity Profile of Chlorhexidine and Propamidine Isethionate Eye Drops.

scientific article published in April 2017

In vitro and in vivo ocular safety and eye surface permanence determination by direct and Magnetic Resonance Imaging of ion-sensitive hydrogels based on gellan gum and kappa-carrageenan.

scientific article published on 14 June 2015

In vivo eye surface residence determination by high-resolution scintigraphy of a novel ion-sensitive hydrogel based on gellan gum and kappa-carrageenan

scientific article published on 8 February 2017

Intravitreal anti-VEGF drug delivery systems for age-related macular degeneration

scientific article published on 26 October 2019

Kinetics of anhydride formation in xerogels of poly(acrylic acid).

scientific article published in September 1996

Longitudinal PET/CT evaluation of TNBS-induced inflammatory bowel disease rat model

scientific article published on 03 August 2018

Microstructural alterations in the onychomycotic and psoriatic nail: relevance in drug delivery.

scientific article published on 16 April 2018

Mucoadhesive Tablets for Controlled Release of Acyclovir

scientific article published on August 2, 2012

Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management

scientific article published on 23 February 2020

Natural & synthetically-modified cyclodextrins and polymers in drug delivery systems

scientific article published on 01 January 2014

Novel Polymeric Formulation for Removal of Gastrointestinal Polyps by Digestive Endoscopy

scientific article published on 02 April 2020

Ocular Biodistribution Studies using Molecular Imaging

scientific article published on 16 May 2019

Ocular safety comparison of non-steroidal anti-inflammatory eye drops used in pseudophakic cystoid macular edema prevention.

scientific article published on 28 September 2015

Ophthalmic econazole hydrogels for the treatment of fungal keratitis.

scientific article published on 3 January 2018

Optimization of Drug Permeation from 8% Ciclopirox Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers

scientific article published on 05 March 2020

PEGylated PLGA nanoparticles as a smart carrier to increase the cellular uptake of a coumarin-based monoamine oxidase B inhibitor

scientific article published on 09 November 2018

Pharmacokinetic model of florfenicol in turbot (Scophthalmus maximus): establishment of optimal dosage and administration in medicated feed.

scientific article published on 9 August 2016

Pharmacokinetics of Intravitreal Anti-VEGF Drugs in Age-Related Macular Degeneration

scientific article published on 31 July 2019

Polyurethanes as New Excipients in Nail Therapeutics

scientific article published on 13 December 2018

Positron Emission Tomography for the Development and Characterization of Corneal Permanence of Ophthalmic Pharmaceutical Formulations.

scientific article published on February 2017

Preclinical PET Study of Intravitreal Injections.

scientific article published in June 2017

Preclinical characterization and clinical evaluation of tacrolimus eye drops

scientific article published on 26 April 2018

Proteomic Analysis in Morquio A Cells Treated with Immobilized Enzymatic Replacement Therapy on Nanostructured Lipid Systems

scientific article published on 18 September 2019

Recent Research in Ocular Cystinosis: Drug Delivery Systems, Cysteamine Detection Methods and Future Perspectives

scientific article published on 03 December 2020

Review of Intraocular Pharmacokinetics of Anti-Infectives Commonly Used in the Treatment of Infectious Endophthalmitis.

scientific article published on 29 May 2018

Solid-state characterization of triamcinolone acetonide nanosuspensiones by X-ray spectroscopy, ATR Fourier transforms infrared spectroscopy and differential scanning calorimetry analysis.

scientific article published on 13 September 2017

Starch-dextrin mixtures as base excipients for extrusion-spheronization pellets.

scientific article published in April 2005

Thermogelling hydrogels of cyclodextrin/poloxamer polypseudorotaxanes as aqueous-based nail lacquers: application to the delivery of triamcinolone acetonide and ciclopirox olamine.

scientific article

Transungual Delivery, Anti-Inflammatory Activity, and In Vivo Assessment of a Cyclodextrin Polypseudorotaxanes Nail Lacquer

scientific article published on 04 August 2020

Vaginal residence and pharmacokinetic preclinical study of topical vaginal mucoadhesive W/S emulsions containing ciprofloxacin

scientific article published on 10 November 2018

[Analysis of ocular toxicity of fluconazole and voriconazole eyedrops using HET-CAM]

scientific article published on 01 July 2014

[Capsaicin topical cream (8%) for the treatment of myofascial pain syndrome]

scientific article published on 10 September 2019

[Ophthalmic formulations new goals]

scientific article published on 01 January 2016