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List of works by Michael Finley

A novel series of pyrazolylpiperidine N-type calcium channel blockers.

scientific article published on 2 May 2012

An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists.

scientific article

Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep).

scientific article published on 15 April 2015

Cell biology. Fusion without SNAREs?

scientific article published on 01 November 2001

Development of a Platform to Enable Fully Automated Cross-Titration Experiments

scientific article published on 19 November 2016

Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors

scientific article published on 28 March 2014

Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel

scientific article published on 27 March 2014

Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Ca 2.2) blockers for the treatment of pain

article

Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects

scientific article published on 24 October 2016

Functional validation of adult hippocampal organotypic cultures as an in vitro model of brain injury.

scientific article published in March 2004

High-Throughput Agonist Shift Assay Development for the Analysis of M1-Positive Allosteric Modulators

scientific article published on 20 April 2017

High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays.

scientific article published on 19 February 2015

Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening

scientific article published on 29 December 2016

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

scientific article published on 9 February 2016

Meeting Proceedings from ICBS 2018- Toward Translational Impact

scientific article published on 12 March 2019

Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.

scientific article

Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)

scientific article

Phosphorylated syntaxin 1 is localized to discrete domains along a subset of axons.

scientific article published on June 2000

Prospective Assessment of Virtual Screening Heuristics Derived Using a Novel Fusion Score

scientific article published on 20 April 2017

QPatch: the missing link between HTS and ion channel drug discovery.

scientific article published on January 2009

SNAP-25 Ser187 does not mediate phorbol ester enhancement of hippocampal synaptic transmission ⬇️

scientific article published on November 1, 2003

Synapse formation and establishment of neuronal polarity by P19 embryonic carcinoma cells and embryonic stem cells

scientific article published on February 1996

The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics.

scientific article published in February 2002

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