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List of works by Rafael Pelaez Lamamie De Clairac Arroyo

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

scientific article

A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

scientific article published on 12 November 2014

A versatile approach to the synthesis of combretastatins

scientific article published on 01 August 1994

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

scientific article published on 18 May 2016

Anti-human herpesvirus 6A/B IgG correlates with relapses and progression in multiple sclerosis

scientific article (publication date: 2014)

Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target

scientific article published on 25 October 2018

CD40: novel association with Crohn's disease and replication in multiple sclerosis susceptibility

scientific article

CD46 in a Spanish cohort of multiple sclerosis patients: genetics, mRNA expression and response to interferon-beta treatment

scientific article published on 21 December 2010

Correction: CD40: Novel Association with Crohn's Disease and Replication in Multiple Sclerosis Susceptibility

scientific article published on 18 August 2010

DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands

scientific article

Design of New Chemoinformatic Tools for the Analysis of Virtual Screening Studies: Application to Tubulin Inhibitors

Design, synthesis and cytotoxic activities of naphthyl analogues of combretastatin A-4

scientific article published on 01 November 2000

Environment-gene interaction in multiple sclerosis: human herpesvirus 6 and MHC2TA

scientific article published on 21 June 2007

Fine mapping and functional analysis of the multiple sclerosis risk gene CD6

scientific article

Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1

scientific article (publication date: 2012)

HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV.

scientific article published on 09 January 2014

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

scientific article published on 19 April 2014

Herpesvirus active replication in multiple sclerosis

scientific article published on 01 October 2011

Heterolignanolides: antitumor activity of furyl-, thienyl-, and pyridyl analogs of lignanolides

scientific article published on 01 May 1995

Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis

scientific article

Human herpesvirus 6 and multiple sclerosis: a one-year follow-up study.

scientific article

Human herpesvirus-6 and multiple sclerosis: relapsing-remitting versus secondary progressive

scientific article published on 16 February 2007

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

scientific article published on 17 November 2012

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.

scientific article

Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.

scientific article

JC virus in cerebrospinal fluid samples of multiple sclerosis patients at the first demyelinating event.

scientific article

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

scientific article

MHC2TA mRNA levels and human herpesvirus 6 in multiple sclerosis patients treated with interferon beta along two-year follow-up.

scientific article

Multiple sclerosis retrovirus-like envelope gene: Role of the chromosome 20 insertion

scientific article

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles.

scientific article

New ligands of the tubulin colchicine site based on X-ray structures.

scientific article published on January 2014

Open analogues of arcyriaflavin A. Synthesis through Diels-Alder reaction between maleimides and 1-aryl-3-tert-butyldimethylsiloxy-1, 3-butadienes

scientific article published on 01 June 2000

Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk

scientific article

Pyridine Based Antitumour Compounds Acting at the Colchicine Site.

scientific article published on January 2016

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

article

Role of the MHC2TA gene in autoimmune diseases.

scientific article published on 29 September 2006

Role of the human endogenous retrovirus HERV-K18 in autoimmune disease susceptibility: study in the Spanish population and meta-analysis.

scientific article

Study of the anti-JCV antibody levels in a Spanish multiple sclerosis cohort.

scientific article published on 30 December 2016

Synthesis and cytotoxic activities of analogues of thuriferic acid

scientific article published in February 2002

Synthesis and pharmacological activity of diarylindole derivatives. Cytotoxic agents based on combretastatins

scientific article published on 01 August 1999

Synthesis of imidazo[4,5-d]oxazolo[3,4-a]pyridines. New heterocyclic analogues of lignans

scientific article published in May 2001

Synthesis, antitumoral and antiviral evaluation of halo- and demethyl-yatein derivatives

scientific article published on 01 September 1995

Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.

scientific article published on 28 April 2010

Visual Evaluation of Clustered Molecules in the Process of New Drugs Design

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