Data from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Data from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Data from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Data from Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer

Data from Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer

Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Evolution of kinase polypharmacology across HSP90 drug discovery

Figure 1 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure 2 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure 3 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure 4 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure 5 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure 6 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Figure S1 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S1 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S2 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S2 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S3 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S3 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S4 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S4 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S5 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Figure S5 from HER3 Is an Actionable Target in Advanced Prostate Cancer

Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome

R-loop editing by DNA cytosine deaminase APOBEC3B determines the activity of estrogen receptor enhancers

Supplementary Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Supplementary Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Supplementary Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Supplementary Data from HER3 Is an Actionable Target in Advanced Prostate Cancer

Supplementary Data from Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer

Supplementary Data from Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer

Supplementary Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Supplementary Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Supplementary Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Supplementary Data from Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Supplementary Figure S1 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S10 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S2 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S3 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S4 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S5 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S6 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S7 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S8 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figure S9 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Supplementary Figures 1-12 from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Supplementary Figures 1-12 from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Supplementary Tables 1-5 from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Supplementary Tables 1-5 from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Supplementary Tables S1-S13 from NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth