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List of works by Francesco Annunziato

A case report of long-term remission of ulcerative colitis after lymphocyto-plasmapheresis

scientific article published in February 2007

Activation of HIV expression by CD30 triggering in CD4+ T cells from HIV-infected individuals

scientific article published on 01 August 1995

Activation of p38(MAPK) mediates the angiostatic effect of the chemokine receptor CXCR3-B.

scientific article

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

scientific article

An update on human Th1 and Th2 cells.

scientific article published on May 1997

Antigen-driven PD-1+TOX+BHLHE40+ and PD-1+TOX+EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ

scientific article published on 09 December 2020

Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells.

scientific article published on 16 December 2004

Biological and clinical significance of T helper 17 cell plasticity

scientific article published on 14 October 2019

Biologicals targeting type 2 immunity: Lessons learned from asthma, chronic urticaria and atopic dermatitis

scientific article published on 12 August 2019

Brief report: etanercept inhibits the tumor necrosis factor α-driven shift of Th17 lymphocytes toward a nonclassic Th1 phenotype in juvenile idiopathic arthritis

scientific article published on 01 May 2014

CD14+CD34 low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors

scientific article published on 14 July 2005

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

scientific article published on 01 August 2010

CD4+CD161+ T lymphocytes infiltrate Crohn's disease-associated perianal fistulas and are reduced by anti-TNF-α local therapy

scientific article published on 15 December 2012

CXC chemokines: the regulatory link between inflammation and angiogenesis.

scientific article published on April 2004

CXCR3 and its binding chemokines in myeloma cells: expression of isoforms and potential relationships with myeloma cell proliferation and survival

scientific article published on November 2006

CXCR3-mediated opposite effects of CXCL10 and CXCL4 on T1 or T2 cytokine production

scientific article published on 01 December 2005

Cell therapy for cardiac regeneration after myocardial infarct: which cell is the best?

scientific article published on October 2010

Cell-mediated and humoral adaptive immune responses to SARS-CoV-2 are lower in asymptomatic than symptomatic COVID-19 patients

scientific article published on 20 October 2020

Characterization of human adult stem-cell populations isolated from visceral and subcutaneous adipose tissue

scientific article published on 7 July 2009

Chemoattractant receptors expressed on type 2 T cells and their role in disease.

scientific article

Chemokines and lymphopoiesis in human thymus.

scientific article

Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

scientific article published on 8 November 2016

Compassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study

scientific article published on 19 August 2020

Connecting with the immunological community.

scientific article published in January 2018

Cytokines and chemokines in T lymphopoiesis and T-cell effector function

scientific article published on 01 September 2000

Defining the human T helper 17 cell phenotype.

scientific article published on 07 June 2012

Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells.

scientific article published on 4 March 2015

Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals

scientific article published on 02 July 2007

Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes

scientific article published on 01 February 2003

Detection by flow cytometry of ESAT-6- and PPD-specific circulating CD4+ T lymphocytes as a diagnostic tool for tuberculosis.

scientific article

Disseminated Mycobacterium xenopi in an Adult with IL-12Rβ1 Deficiency

scientific article published on 27 August 2020

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

scientific article published on 25 October 2012

Do studies in humans better depict Th17 cells?

scientific article published on 03 June 2009

Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound.

scientific article

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.

scientific article

Efficacy and Safety of Mepolizumab (Anti-Interleukin-5) Treatment in Gleich's Syndrome.

scientific article

Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells.

scientific article published on 27 March 2008

Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury.

scientific article published on 9 April 2018

Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression.

scientific article published on April 2008

Enhanced expression of the CXCR4 co-receptor in HIV-1-infected individuals correlates with the emergence of syncytia-inducing strains

scientific article published on 01 March 2000

Eomes controls the development of Th17-derived (non-classic) Th1 cells during chronic inflammation

article

Evidence for a cross-talk between human neutrophils and Th17 cells

article

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

scientific article published on 01 August 2011

Expression of the chemokine CCL21 during chronic hepatitis C: potential role in inflammation and fibrosis

Facilitating Processes and Extending Boundaries at EJI

scientific article published on 01 January 2017

Frequency of regulatory T cells in peripheral blood and in tumour-infiltrating lymphocytes correlates with poor prognosis in renal cell carcinoma.

scientific article published on 24 August 2010

Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria

scholarly article

Functional features of human CD25+ regulatory thymocytes

scientific article

Group 2 Innate Lymphoid Cells Are the Earliest Recruiters of Eosinophils in Lungs of Patients with Allergic Asthma

scientific article published on 01 September 2017

Group 2 Innate Lymphoid Cells: A Double-Edged Sword in Cancer?

scientific article published on 20 November 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

Heterogeneity of human effector CD4+ T cells.

scientific article published on 09 December 2009

High intracytoplasmatic levels of Il-4 and Il-5 in a patient with Gleichs syndrome: case report

scientific article published on 01 October 2006

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

scientific article published on 31 July 2003

Human T cells interacting with HNSCC-derived mesenchymal stromal cells acquire Tissue-Resident memory like properties

scientific article published on 22 May 2020

Human Th1 dichotomy: origin, phenotype and biologic activities

scientific article published on 05 October 2014

Human Th17 cells: are they different from murine Th17 cells?

scientific article published in March 2009

Human and murine Th17.

scientific article published on March 2010

Human circulating group 2 innate lymphoid cells can express CD154 and promote IgE production

scientific article published on 27 July 2016

Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction

scientific article published on 04 March 2008

Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

scientific article published on 28 July 2008

Human neutrophils activated via TLR8 promote Th17 polarization through IL-23

scientific article published on 28 February 2019

Hypergravity speeds up the development of T-lymphocyte motility

article

IL-1 and T Helper Immune Responses

scientific article published on 15 July 2013

IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes.

scientific article published in August 2007

IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells.

scientific article

IP-10 and Mig production by glomerular cells in human proliferative glomerulonephritis and regulation by nitric oxide

scientific article published in January 2002

Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4.

scientific article published in January 2010

Immune Regulation by Mesenchymal Stem Cells Derived from Adult Spleen and Thymus

scientific article published on 01 October 2007

Immunomodulation: a new approach to the therapy of cirrhosis?

scientific article published on 01 July 2010

Immunosuppression in cardiac graft rejection: a human in vitro model to study the potential use of new immunomodulatory drugs.

scientific article

Immunosuppressive Activity of Abatacept on Circulating T Helper Lymphocytes from Juvenile Idiopathic Arthritis Patients.

scientific article published on 8 November 2016

Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

scientific article published on 28 May 2020

In vitro effects of etanercept on the development of different T cell subsets in patients with juvenile idiopathic arthritis

Increased risk of lymphoid neoplasms in patients with Philadelphia chromosome-negative myeloproliferative neoplasms.

scientific article published on 16 June 2009

Infection with SARS-CoV-2 Variants Is Associated with Different Long COVID Phenotypes

scientific article published in 2022

Influence of both TCR repertoire and severity of the atopic status on the cytokine secretion profile of Parietaria officinalis-specific T cells

scientific article published on 01 January 1998

Inhibitors of the PI3K/mTOR pathway prevent STAT5 phosphorylation in JAK2V617F mutated cells through PP2A/CIP2A axis

scientific article published on 22 May 2017

Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta+ CD8+ single-positive T cells, [...]

scientific article (publication date: February 2001)

Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys

scientific article

Kaposi sarcoma in a patient treated with ruxolitinib

scientific article published on 01 July 2017

Letters to the editor: Publish fast.

scientific article published in February 2018

Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-γ memory in human CD4(+) T lymphocytes.

scientific article published in March 2013

MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells.

scientific article published on 2 May 2012

Macrophage-derived chemokine production by activated human T cellsin vitro andin vivo: preferential association with the production of type 2 cytokines

article

Main features of human T helper 17 cells.

scientific article published in May 2013

Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis

scientific article published on 01 October 2004

Mesenchymal stem cells are enriched in head neck squamous cell carcinoma, correlates with tumour size and inhibit T-cell proliferation

scientific article

Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab

scientific article

Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes

scientific article

Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7.

scientific article

Molecular mechanisms underlying the pro-inflammatory synergistic effect of tumor necrosis factor alpha and interferon gamma in human microvascular endothelium

scientific article published on 26 September 2009

Mouse T helper 17 phenotype: not so different than in man after all.

scientific article published on 02 August 2011

Multilineage Dysplasia as Assessed by Immunophenotype in Acute Myeloid Leukemia: A Prognostic Tool in a Genetically Undefined Category

scientific article published on 30 October 2020

Multiorgan infiltration by CD8+ T cells and 1p;16p translocation in a patient with hypogammaglobulinemia and a reduced number of B cells.

scientific article published on 26 January 2012

Musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity

scientific article published on 14 June 2017

Myelodysplasia as assessed by multiparameter flow cytometry refines prognostic stratification provided by genotypic risk in systemic mastocytosis

scientific article published on 21 May 2019

Omalizumab dampens type 2 inflammation in a group of long-term treated asthma patients and detaches IgE from FcεRI

scientific article published on 09 October 2018

Opposite role for interleukin-4 and interferon-gamma on CD30 and lymphocyte activation gene-3 (LAG-3) expression by activated naive T cells.

scientific article

Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium

scientific article published on 15 August 2016

PF-4/CXCL4 and CXCL4L1 exhibit distinct subcellular localization and a differentially regulated mechanism of secretion

scientific article published on 11 January 2007

Perianal Crohn's disease and hidradenitis suppurativa: a possible common immunological scenario.

scientific article published on 22 July 2015

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

scientific article

Plasticity and regulatory mechanisms of human ILC2 functions

scientific article published on 18 August 2020

Polyinosinic acid: polycytidylic acid promotes T helper type 1-specific immune responses by stimulating macrophage production of interferon-alpha and interleukin-12

scientific article published on 01 September 1995

Prompt predicting of early clinical deterioration of moderate-to-severe COVID-19 patients: usefulness of a combined score using IL-6 in a preliminary study

scientific article published on 18 June 2020

Properties and origin of human Th17 cells

scientific article published on 03 February 2009

Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab

scientific article published on 05 November 2020

Quantitative and qualitative alterations of circulating myeloid cells and plasmacytoid DC in SARS-CoV-2 infection

scientific article published on 01 September 2020

Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

scientific article published on 09 February 2012

Reasons for rarity of Th17 cells in inflammatory sites of human disorders.

scientific article

Redirection of allergen-specific TH2 responses by a modified adenine through Toll-like receptor 7 interaction and IL-12/IFN release.

scientific article published on August 2006

Regenerative Potential of Embryonic Renal Multipotent Progenitors in Acute Renal Failure

scientific article published on 31 October 2007

Regenerative and immunomodulatory potential of mesenchymal stem cells

scientific article published on 13 June 2006

Research needs in allergy: an EAACI position paper, in collaboration with EFA.

scientific article published on 2 November 2012

Reversal of human allergen-specific CRTH2+ T(H)2 cells by IL-12 or the PS-DSP30 oligodeoxynucleotide.

scientific article

Role for CD30 in HIV expression.

scientific article published on June 1996

Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.

scientific article published on 25 August 2005

Role of IL12 in the development of human Th1 type cells.

scientific article published on September 1995

Role of TH1/TH2 cytokines in HIV infection.

scientific article published on August 1994

Role of Type 2 Innate Lymphoid Cells in Allergic Diseases

scientific article published on 11 September 2017

Sphingosine Kinases promote IL-17 expression in human T lymphocytes

scientific article published in Scientific Reports

Strategies for T Helper Cell Subset Differentiation from Naïve Precursors.

scientific article published in January 2017

T cell subpopulations in juvenile idiopathic arthritis and their modifications after biotherapies

scientific article published on 15 September 2016

T helper cells plasticity in inflammation.

scientific article published on 05 September 2013

T-cell clones from Th1, Th17 or Th1/17 lineages and their signature cytokines have different capacity to activate endothelial cells or synoviocytes.

scientific article published on 28 September 2016

TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells.

scientific article

Th1-Induced CD106 Expression Mediates Leukocytes Adhesion on Synovial Fibroblasts from Juvenile Idiopathic Arthritis Patients.

scientific article

Th17 and Th1 Lymphocytes in Oligoarticular Juvenile Idiopathic Arthritis

scientific article published on 14 March 2019

Th17 and non-classic Th1 cells in chronic inflammatory disorders: two sides of the same coin

scientific article published on 12 July 2014

Th17 cells: new players in asthma pathogenesis ⬇️

scientific article published on 06 March 2011

Th17 lymphocyte-dependent degradation of joint cartilage by synovial fibroblasts in a humanized mouse model of arthritis and reversal by secukinumab

scientific article published on 20 July 2020

Th17 plasticity: pathophysiology and treatment of chronic inflammatory disorders.

scientific article published on 28 June 2014

Th17 regulating lower airway disease.

scientific article

Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines

scientific article

The 3 major types of innate and adaptive cell-mediated effector immunity

scientific article published on 18 December 2014

The COVID-19 infection: lessons from the Italian experience

scientific article published on 29 May 2020

The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.

scientific article

The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection ⬇️

scientific article published on 26 November 2020

The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.

scientific article published in October 2003

The global response to the COVID-19 pandemic: how have immunology societies contributed?

scientific article published on 10 September 2020

The intestinal expansion of TCRγδ+ and disappearance of IL4+ T cells suggest their involvement in the evolution from potential to overt celiac disease

scientific article published on 25 October 2019

The management of paediatric allergy

scientific article published on 01 March 2013

The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells.

scientific article published on February 2003

The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation.

scientific article published on 26 September 2008

The protease systems and their pathogenic role in juvenile idiopathic arthritis

scientific article published on 08 June 2019

The transient nature of the Th17 phenotype.

scientific article published in December 2010

Therapeutic Efficacy of Autologous Non-Mobilized Enriched Circulating Endothelial Progenitors in Patients With Critical Limb Ischemia　- The SCELTA Trial

scientific article published on 23 March 2018

Thymic regulatory T cells

scientific article

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

scientific article published on 25 October 2007

Type 17 T helper cells-origins, features and possible roles in rheumatic disease

scientific article published on June 2009

Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.

scientific article published on July 2002

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