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List of works by Lukasz Lebioda

Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using “Peroxidase-like” Myoglobin Mutants and “Myoglobin-like” DHP Mutants ⬇️

scientific article published on August 30, 2011

An X-ray absorption spectroscopy study of the interactions of Ni2+ with yeast enolase

scientific article published on 01 May 1995

An enzymatic globin from a marine worm

scientific article published on 01 September 1999

Bio–incorporation of telluromethionine into buried residues of dihydrofolate reductase ⬇️

scientific article published on May 1, 1994

Calculated effects of the chemical environment of 2-phospho-D-glycerate on the pKa of its carbon-2 and correlations with the proposed mechanism of action of enolase

scientific article published on 01 June 1995

Catalytic cysteine of thymidylate synthase is activated upon substrate binding

scientific article

Catalytic metal ion binding in enolase: the crystal structure of an enolase-Mn2+-phosphonoacetohydroxamate complex at 2.4-A resolution

scientific article

Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica

scientific article

Characterization and inactivation of an agmatine deiminase from Helicobacter pylori

scientific article

Comparison of the folding of 2-keto-3-deoxy-6-phosphogluconate aldolase, triosephosphate isomerase and pyruvate kinase. Implications in molecular evolution

scientific article

Complex of myoglobin with phenol bound in a proximal cavity ⬇️

scientific article published on November 19, 2012

Complexes of dual-function hemoglobin/dehaloperoxidase with substrate 2,4,6-trichlorophenol are inhibitory and indicate binding of halophenol to compound I

scientific article

Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors

scientific article

Crystal structure of a covalent intermediate of endogenous human arylsulfatase A

scientific article

Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding

scientific article

Crystal structure of enolase indicates that enolase and pyruvate kinase evolved from a common ancestor

scientific article published in Nature

Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site

scientific article

Crystal structure of human prostatic acid phosphatase

scientific article

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

scientific article

Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design

scientific article

Crystallization and crystallographic data for new forms of thymidylate synthase from Lactobacillus casei

scientific article

Crystallization and initial spectroscopic characterization of the heme-containing dehaloperoxidase from the marine polychaete Amphitrite ornata

scientific article published on 01 November 1996

Crystallization and preliminary crystallographic data for a tetragonal form of yeast enolase

scientific article published on November 1984

Crystallization and preliminary crystallographic data for formyltetrahydrofolate synthetase from Clostridium thermoaceticum

scientific article published on February 1993

Crystallization at low salt concentration and alkaline pH and preliminary crystallographic data for a monoclinic form of yeast enolase

scientific article

Crystallization of alcohol oxidase from Pichia pastoris. Secondary structure predictions indicate a domain with the eightfold beta/alpha-barrel fold

Data mining of metal ion environments present in protein structures

scientific article

Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254

scientific article

Effect of site-directed mutagenesis of His373 of yeast enolase on some of its physical and enzymatic properties ⬇️

scientific article published on June 20, 1997

Effects of ligand binding and conformational switching on intracellular stability of human thymidylate synthase.

scientific article published on January 2004

Enzymatic function of loop movement in enolase: preparation and some properties of H159N, H159A, H159F, and N207A enolases

scientific article published in May 2003

Evolution of Metamorphism in Thymidylate Synthases Within the Primate Lineages ⬇️

scientific article published on February 12, 2011

Expression, characterization and crystallographic analysis of telluromethionyl dihydrofolate reductase

scientific article published in September 1995

Expression, purification and the 1.8 angstroms resolution crystal structure of human neuron specific enolase

scientific article

Fluoride inhibition of enolase: crystal structure and thermodynamics

scientific article published on January 2006

Fluoride inhibition of yeast enolase: crystal structure of the enolase-Mg(2+)-F(-)-Pi complex at 2.6 A resolution

scientific article

Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug

scientific article

Human thymidylate synthase with loop 181–197 stabilized in an inactive conformation: Ligand interactions, phosphorylation, and inhibition profiles ⬇️

scientific article published on January 1, 2011

Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin

scientific article published on 01 March 1993

Influence of heme environment structure on dioxygen affinity for the dual function Amphitrite ornata hemoglobin/dehaloperoxidase. Insights into the evolutional structure-function adaptations

scientific article

Inhibition of enolase: the crystal structures of enolase-Ca2(+)- 2-phosphoglycerate and enolase-Zn2(+)-phosphoglycolate complexes at 2.2-A resolution

scientific article

Ion binding induces closed conformation in Pseudomonas 7A glutaminase-asparaginase (PGA): crystal structure of the PGA-SO4(2-)-NH4+ complex at 1.7 A resolution

scientific article

Mapping of isozymic differences in enolase

scientific article published on 01 April 1991

Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors

scientific article

Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution

scientific article

Mechanism of enolase: the crystal structure of enolase-Mg2(+)-2-phosphoglycerate/phosphoenolpyruvate complex at 2.2-A resolution

scientific article

Molecular Characterization of a Novel Short-chain Dehydrogenase/Reductase That Reduces All-trans-retinal ⬇️

scientific article published on August 21, 1998

Preparation and characterization of the E168Q site-directed mutant of yeast enolase 1

scientific article published on 01 December 1993

Preparation by site-directed mutagenesis and characterization of the E211Q mutant of yeast enolase 1 ⬇️

scientific article published on August 16, 1995

Prostatic acid phosphatase: structural aspects of inhibition by L-(+)-tartrate ions

scientific article published on 01 January 1997

Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu

scientific article

Refined structure of yeast apo-enolase at 2.25 A resolution

scientific article

Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability,

scientific article

Response to boguslaw stec's letter to the editor of protein science ⬇️

scientific article published on April 29, 2013

Significance of the enzymatic properties of yeast S39A enolase to the catalytic mechanism ⬇️

scientific article published on 01 April 1998

Structural Origins of l(+)-Tartrate Inhibition of Human Prostatic Acid Phosphatase ⬇️

scientific article published on November 13, 1998

Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis

scientific article

Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family

scientific article

Structure of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Pseudomonas putida

scientific article

Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase at 2 . 8 A resolution

scientific article

Structure of Human C8 Protein Provides Mechanistic Insight into Membrane Pore Formation by Complement ⬇️

scientific article published on March 25, 2011

Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors

scientific article

Structure of human thymidylate synthase under low-salt conditions

scientific article published on 20 April 2005

Structure of the thioredoxin-like domain of yeast glutaredoxin 3

scientific article

Structures of K42N and K42Y sperm whale myoglobins point to an inhibitory role of distal water in peroxidase activity

scientific article

Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity ⬇️

scientific article published on February 24, 2012

Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding ⬇️

scientific article published on December 16, 2010

Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins

scientific article published on March 2006

Telluromethionine in structural biochemistry.

scientific article

The H159A mutant of yeast enolase 1 has significant activity

scientific article published on 01 October 2000

The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195 † ‡

scientific article

The X-ray structural investigation of 6-(n,n-1,6-hexyleneformamidine)-penicillanic acid (mecillinam)

scientific article published on 01 March 1981

The crystal structure and amino acid sequence of dehaloperoxidase from Amphitrite ornata indicate common ancestry with globins

scientific article

The crystal structure of N(10)-formyltetrahydrofolate synthetase from Moorella thermoacetica

scientific article

The honorary enzyme haemoglobin turns out to be a real enzyme

scientific article published on 01 December 2000

The structure of yeast enolase at 2.25-A resolution. An 8-fold beta + alpha-barrel with a novel beta beta alpha alpha (beta alpha)6 topology

scientific article

Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation

scientific article

X-ray crystal structure of sangivamycin, a potent inhibitor of protein kinases

scientific article published on 01 June 1990

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