List of works - Paul L. Modrich

12 Purification and properties of EcoRI endonuclease

scientific article published on 01 January 1980

A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype ⬇️

scientific article published on March 1, 1998

Christian Raetz: Scientist and Friend Extraordinaire ⬇️

scientific article published on March 7, 2013

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair ⬇️

scientific article published on September 16, 1997

Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation ⬇️

scientific article published on 09 July 2013

High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6 ⬇️

scientific article published on November 20, 2001

Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion

scientific article published on 03 February 2020

Hydrolytic function of Exo1 in mammalian mismatch repair.

scientific article

Hydrolytically Deficient MutS E694A Is Defective in the MutL-dependent Activation of MutH and in the Mismatch-dependent Assembly of the MutS · MutL · Heteroduplex Complex ⬇️

scientific article published on September 23, 2003

Increased transversions in a novel mutator colon cancer cell line ⬇️

scientific article published on March 5, 1998

Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair.

scientific article

Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα ⬇️

scientific article published on July 31, 1998

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells ⬇️

scientific article published on June 30, 1995

Mechanisms and biological effects of mismatch repair ⬇️

scientific article published on January 1, 1991

Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture).

scientific article published on 20 May 2016

Methyl-directed repair of DNA base-pair mismatches in vitro ⬇️

scientific article published on August 1, 1983

Mismatch Repair Deficiency in Phenotypically Normal Human Cells ⬇️

scientific article published on May 5, 1995

Mismatch-, MutS-, MutL-, and Helicase II-dependent Unwinding from the Single-strand Break of an Incised Heteroduplex ⬇️

scientific article published on April 10, 1998

MutS and MutL Activate DNA Helicase II in a Mismatch-dependent Manner ⬇️

scientific article published on April 10, 1998

MutS mediates heteroduplex loop formation by a translocation mechanism ⬇️

scientific article published on July 16, 1997

PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro ⬇️

scientific article published on September 25, 2011

Preliminary X-ray diffraction studies of EcoRI restriction endonuclease-DNA complex ⬇️

scientific article published on January 25, 1981

Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ ⬇️

scientific article published on July 26, 2011

Strand-specific Mismatch Repair in Mammalian Cells ⬇️

scientific article published on October 3, 1997

Structures and mechanisms of DNA restriction and modification enzymes ⬇️

scientific article published on August 1, 1979

Studies on Sequence Recognition By Type II Restriction and Modification Enzyme ⬇️

scientific article published on January 1, 1982

Substrate dependence of the mechanism of EcoRI endonuclease ⬇️

scientific article published on August 1, 1978

The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

scientific article published on 27 April 2016

The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease.

scientific article published on 25 June 2018

Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors ⬇️

scientific article published on January 1, 1998

List of works by Paul L. Modrich