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List of works by Rob Pieters

A cost analysis of individualized asparaginase treatment in pediatric acute lymphoblastic leukemia

scientific article

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

scientific article published on 21 January 2014

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

scientific article

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial

scientific article published in July 2007

Abdominal Radiotherapy: A Major Determinant of Metabolic Syndrome in Nephroblastoma and Neuroblastoma Survivors ⬇️

scientific article published on December 14, 2012

Abl-interactor 2 (ABI2): a novel MLL translocation partner in acute myeloid leukemia

scientific article published in February 2012

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia

scientific article published on 28 November 2012

Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.

scientific article

Acute Activation of Metabolic Syndrome Components in Pediatric Acute Lymphoblastic Leukemia Patients Treated with Dexamethasone

scientific article

Acute lymphoblastic leukaemia in children and adolescents: chance of cure now higher than 80%

scientific article published on January 1, 2010

Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis

scientific article published on 15 June 2017

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

scientific article

Adrenal function in adult long-term survivors of nephroblastoma and neuroblastoma ⬇️

scientific article published on April 16, 2012

Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia

scientific article

Allergic-like reactions to asparaginase: Atypical allergies without asparaginase inactivation

scientific article published on 4 July 2016

Alterations in epithelial and mesenchymal intestinal gene expression during doxorubicin-induced mucositis in mice

scientific article published on 6 April 2007

Anaplastic lymphoma kinase (ALK) inhibitor response in neuroblastoma is highly correlated with ALK mutation status, ALK mRNA and protein levels ⬇️

scientific article published on May 31, 2011

Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia

scientific article

Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia

scientific article published on 4 December 2009

Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1 driven B-cell precursor acute lymphoblastic leukemia

scholarly article by Roel Polak et al published 31 October 2018 in Haematologica

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

scientific article published on 21 August 2015

BCOR and BCORL1 mutations in pediatric acute myeloid leukemia

scientific article published on 16 January 2015

BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures

scientific article published on 4 June 2015

Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective

scientific article

Biology and treatment of acute lymphoblastic leukemia

scientific article published on February 2008

Biology and treatment of acute lymphoblastic leukemia

scientific article published on February 2010

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

scientific article

Bone mineral density at diagnosis determines fracture rate in children with acute lymphoblastic leukemia treated according to the DCOG-ALL9 protocol

scientific article published on 25 November 2013

Bone mineral density, growth, and thyroid function in long-term survivors of pediatric Hodgkin's lymphoma treated with chemotherapy only

scientific article published on 17 March 2009

CD34 expression is associated with poor survival in pediatric T-cell acute lymphoblastic leukemia.

scientific article

Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities

scientific article published in November 2002

Changes in hypercoagulability by asparaginase: a randomized study between two asparaginases

scientific article published in March 2006

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

scientific article

Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements ⬇️

scientific article published on November 4, 2011

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

scientific article

Clinical and molecular genetic characterization of wild-type MLL infant acute lymphoblastic leukemia identifies few recurrent abnormalities

scientific article published on 17 December 2015

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

scientific article

Clustering of hypermethylated genes in neuroblastoma ⬇️

scientific article published on November 1, 2003

Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation

scientific article published on March 2016

Contributions of mucosal immune cells to methotrexate-induced mucositis.

scientific article

Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia

Cost-analysis of treatment of childhood acute lymphoblastic leukemia with asparaginase preparations: the impact of expensive chemotherapy ⬇️

scientific article published on February 12, 2013

D-HPLC analysis of the entire FLT3 gene in MLL rearranged and hyperdiploid acute lymphoblastic leukemia.

scientific article published in November 2007

Dasatinib in children and adolescents with relapsed or refractory leukemia: results of the CA180-018 phase I dose-escalation study of the Innovative Therapies for Children with Cancer Consortium

scientific article published on 28 May 2013

Decrease in motor performance in children with cancer is independent of the cumulative dose of vincristine

scientific article published on March 2006

Decrease in peripheral muscle strength and ankle dorsiflexion as long-term side effects of treatment for childhood cancer

scientific article published in April 2008

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia

scientific article

Decreased induction morbidity and mortality following modification to induction therapy in infants with acute lymphoblastic leukemia enrolled on AALL0631: a report from the Children's Oncology Group

scientific article published on 18 November 2014

Defects in the DNA Mismatch Repair System Do Not Contribute to the Development of Childhood Wilms Tumors ⬇️

scientific article published on January 1, 2013

Desensitization protocol should not be used in acute lymphoblastic leukemia patients with silent inactivation of PEGasparaginase

scientific article published on 28 March 2014

Determinants of quality of life during induction therapy in pediatric acute lymphoblastic leukemia

scientific article published on 11 July 2014

Diagnosis and management of neonatal leukaemia ⬇️

scientific article published on April 15, 2012

Diagnostic tool for the identification of MLL rearrangements including unknown partner genes

scientific article

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

scientific article published in January 2002

Different outcome in older children with acute lymphoblastic leukemia with different treatment protocols in the Netherlands ⬇️

scientific article published on January 19, 2011

Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis

scientific article

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia

scientific article

Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia ⬇️

scientific article published on August 4, 2011

Disturbed CXCR4/CXCL12 axis in paediatric precursor B-cell acute lymphoblastic leukaemia.

scientific article published on 4 April 2014

Downregulation of Axl in non-MYCN amplified neuroblastoma cell lines reduces migration ⬇️

scientific article published on March 21, 2013

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

scientific article published on 15 April 2007

Eating behavior during dexamethasone treatment in children with acute lymphoblastic leukemia

scientific article published on 9 June 2017

Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia

scientific article published on 29 March 2005

Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

scientific article

Efficacy and safety of recombinant E. coli asparaginase in children with previously untreated acute lymphoblastic leukemia: A randomized multicenter study of the Dutch Childhood Oncology Group.

scientific article

Electroejaculation as a method of fertility preservation in boys diagnosed with cancer: a single-center experience and review of the literature

scientific article published on 26 April 2014

Emotional distress in 652 Dutch very long-term survivors of childhood cancer, using the hospital anxiety and depression scale (HADS).

scientific article published in October 2013

End-of-Life Decisions in Pediatric Cancer Patients

scientific article published on August 2015

Endocrine sequelae and metabolic syndrome in adult long-term survivors of childhood acute myeloid leukemia

scientific article published on 9 January 2013

Epigenetic drug combination induces genome-wide demethylation and altered gene expression in neuro-ectodermal tumor-derived cell lines

scientific article

Erroneous Exchange of Asparaginase Forms in the Treatment of Acute Lymphoblastic Leukemia ⬇️

scientific article published on April 1, 2011

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia

scientific article

Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

scientific article

Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.

scientific article

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols

scientific article

FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance

scientific article

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia

scientific article published in Scientific Reports

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).

scientific article published on April 2004

Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1).

scientific article published on 5 March 2014

Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants ⬇️

scientific article published on February 12, 2013

Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study

scientific article published on 30 December 2011

Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia

scientific article published on November 2005

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

scientific article published on 23 December 2009

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]

scientific article published on September 2008

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

scientific article published on 28 September 2006

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

scientific article

Genetic Biomarkers to Identify the Risk of Osteonecrosis in Children with Acute Lymphoblastic Leukemia

scientific article published on 30 June 2016

Genetic variation and bone mineral density in long-term adult survivors of childhood cancer

scientific article

Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia

scientific article published in August 2005

Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL.

scientific article

Gonadal function in boys with newly diagnosed cancer before the start of treatment

scientific article published on 28 September 2016

Gonadal function recovery in very long-term male survivors of childhood cancer ⬇️

scientific article published on January 5, 2013

HOXA-activated early T-cell progenitor acute lymphoblastic leukemia: predictor of poor outcome?

scientific article published on June 2016

Health-related fitness in very long-term survivors of childhood cancer: A cross-sectional study

scientific article published on 22 December 2017

High Anaplastic Lymphoma Kinase Immunohistochemical Staining in Neuroblastoma and Ganglioneuroblastoma Is an Independent Predictor of Poor Outcome ⬇️

scientific article published on December 25, 2011

High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).

scientific article published on 2 November 2010

High PDGFRA expression does not serve as an effective therapeutic target in ERG-deleted B-cell precursor acute lymphoblastic leukemia

scientific article published on 23 November 2017

High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia

scientific article published on 12 January 2018

High concordance of subtypes of childhood acute lymphoblastic leukemia within families: lessons from sibships with multiple cases of leukemia

scientific article published on 18 October 2011

High frequency of copy number alterations in myeloid leukaemia of Down syndrome.

scientific article

High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.

scientific article

Home-Based Palliative Care for Children With Incurable Cancer: Long-term Perspectives of and Impact on General Practitioners

scientific article published on 29 December 2016

Hydrocortisone as an Intervention for Dexamethasone-Induced Adverse Effects in Pediatric Patients With Acute Lymphoblastic Leukemia: Results of a Double-Blind, Randomized Controlled Trial

scientific article published on 9 May 2016

Hydrocortisone does not influence glucocorticoid sensitivity of acute lymphoblastic leukemia cells

scientific article published on 25 November 2014

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

scientific article

Identification of apolipoprotein A-II in cerebrospinal fluid of pediatric brain tumor patients by protein expression profiling

scientific article

Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia

scientific article

Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia

scientific article

Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteome-wide analysis

scientific article

Identification of tumor-related proteins by proteomic analysis of cerebrospinal fluid from patients with primary brain tumors

scientific article published in August 2003

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

scientific article

Immunophenotyping as a guide for targeted therapy ⬇️

scientific article published on December 1, 2003

Impact of reduced chemotherapy treatment for good risk childhood acute lymphoblastic leukaemia on infectious morbidity* ⬇️

scientific article published on January 11, 2011

Impact of two independent bone marrow samples on minimal residual disease monitoring in childhood acute lymphoblastic leukaemia.

scientific article

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study

scientific article published on 30 June 2010

In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties

scientific article

In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia ⬇️

scientific article published on July 5, 2011

In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia

scientific article published in January 2006

Increased total-Tau levels in cerebrospinal fluid of pediatric hydrocephalus and brain tumor patients

scientific article published on 22 October 2007

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

scientific article published on 23 August 2013

Infant acute lymphoblastic leukemia: Lessons learned and future directions

scientific article published on July 2009

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy

scientific article published on 11 January 2016

Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin's lymphoma with chemotherapy during childhood

scientific article published on 2 November 2007

Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells

scientific article published on 10 June 2013

Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification

scientific article published in February 2003

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

scientific article published on 31 October 2008

Initial Diagnostic Work-Up of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement of the College of American Pathologists and American Society of Hematology Guideline.

scientific article published on 3 December 2018

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia

scientific article published in April 2011

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

scientific article

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 16 September 2017

KIAA1524: A novel MLL translocation partner in acute myeloid leukemia.

scientific article

L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase

scientific article

Letter to the editor: gonadal function after childhood ovarian surgery

scientific article published in September 2013

Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells

scientific article published in February 2005

Long-Term Nephrotoxicity in Adult Survivors of Childhood Cancer ⬇️

scientific article published on February 14, 2013

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

scholarly article by Andrea Biondi et al published January 2019 in Haematologica

Loss of CD44dim Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus

scientific article published on 20 January 2017

Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique.

scientific article published on 16 March 2010

MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations

scientific article published on 31 August 2016

MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

scientific article published on January 2014

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

scientific article published on 03 December 2001

Management and treatment of osteonecrosis in children and adolescents with acute lymphoblastic leukemia

scientific article published on March 2014

Mapping epigenetic regulator gene mutations in cytogenetically normal pediatric acute myeloid leukemia

scientific article published on 9 May 2014

Medical end-of-life decisions for children in the Netherlands

scientific article published in September 2005

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

scientific article published on 29 May 2015

Methotrexate-induced mucositis in mucin 2-deficient mice.

scientific article published in January 2007

Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia

scientific article

MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

scientific article published on 17 January 2011

MicroRNA signature in BCR-ABL1-like and BCR-ABL1-positive childhood acute lymphoblastic leukemia: similarities and dissimilarities.

scientific article

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

scientific article published on 24 June 2016

Microarray-based identification of new targets for specific therapies in pediatric leukemia

scientific article published on June 2007

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

scientific article published on 07 August 2008

Mu class glutathione S-transferase mRNA isoform expression in acute lymphoblastic leukaemia

scientific article

NRIP3: a novel translocation partner of MLL detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements

scientific article published on 19 May 2009

New cellular markers at diagnosis are associated with isolated central nervous system relapse in paediatric B-cell precursor acute lymphoblastic leukaemia

scientific article

New genetic abnormalities and treatment response in acute lymphoblastic leukemia

scientific article published on January 2009

No difference between prednisolone and dexamethasone treatment in bone mineral density and growth in long term survivors of childhood acute lymphoblastic leukemia

scientific article published in January 2006

Novel murine B-cell lymphoma/leukemia model to study BCL2-driven oncogenesis.

scientific article

Obesity Is Underestimated Using Body Mass Index and Waist-Hip Ratio in Long-Term Adult Survivors of Childhood Cancer ⬇️

scientific article published on August 14, 2012

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

scientific article

Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.

scientific article

PHF6 mutations in T-cell acute lymphoblastic leukemia

scientific article (publication date: 14 March 2010)

Palliative care in children with cancer: implications for general practice

scientific article published in December 2016

Parenting stress as a mediator of parents' negative mood state and behavior problems in children with newly diagnosed cancer

scientific article published on 24 January 2014

Parents' Faith and Hope during the Pediatric Palliative Phase and the Association with Long-Term Parental Adjustment

scientific article

Parents' experiences of pediatric palliative care and the impact on long-term parental grief

scientific article

Participation in a clinical trial for a child with cancer is burdensome for a minority of children

scientific article

Pediatric Acute Lymphoblastic Leukemia: Efficacy and safety of recombinant E. coli-asparaginase in infants (less than one year of age) with acute lymphoblastic leukemia

scientific article published on 10 June 2013

Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature

scientific article

Peripheral stem cell harvest using regular chemotherapy schedules in childhood cancer ⬇️

scientific article published on August 9, 2012

Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia

scientific article

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

scientific article published in May 2009

Pharmacokinetics, pharmacodynamics, efficacy, and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia: a randomized phase 2 clinical trial

scientific article published on 19 September 2008

Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia

scientific article published on 19 November 2008

Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

scientific article

Population pharmacokinetics of native Escherichia coli asparaginase

scientific article published in March 2012

Predicting the neurobehavioral side effects of dexamethasone in pediatric acute lymphoblastic leukemia

scientific article published on 11 July 2016

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic l

scholarly article by Giovanni Cazzaniga et al published January 2018 in Haematologica

Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.

scientific article published in October 2007

Prospective Study on Incidence, Risk Factors, and Long-Term Outcome of Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia ⬇️

scientific article published on September 26, 2011

Protection against chemotherapy induced mucositis by TGF-beta(2) in childhood cancer patients: results from a randomized cross-over study.

scientific article

Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia

scientific article published on September 2009

Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study

scientific article

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

scientific article published on 11 June 2015

Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion

scientific article published on 26 November 2015

Reduced versus intensive chemotherapy for childhood acute lymphoblastic leukemia: impact on lymphocyte compartment composition

scientific article published on 3 November 2010

Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia

scientific article published on 14 August 2003

Role of mutation independent constitutive activation of FLT3 in juvenile myelomonocytic leukemia

scientific article published in November 2007

STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia

scientific article published on 5 June 2013

Second malignant neoplasms after treatment of childhood acute lymphoblastic leukemia

scientific article published on 20 May 2013

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

scientific article published on 14 November 2002

Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

scientific article published on 23 October 2009

Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group

scientific article published on 6 June 2016

Sustaining innovation and improvement in the treatment of childhood cancer: lessons from high-income countries

scientific article published on 20 February 2013

TELAML1-positive ALL: a discordant genotype.

scientific article published on 23 August 2005

Talking about Death with Children with Incurable Cancer: Perspectives from Parents.

scientific article

Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia

scientific article

The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis.

scientific article

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

scientific article published on April 2016

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney

scientific article published on 6 November 2015

The effect of cytostatic drug treatment on intestine-specific transcription factors Cdx2, GATA-4 and HNF-1alpha in mice.

scientific article published on 15 September 2005

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

scientific article published on 27 September 2005

The limited screening value of insulin‐like growth factor‐i as a marker for alterations in body composition in very long‐term adult survivors of childhood cancer ⬇️

scientific article published on December 11, 2011

The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97) ⬇️

scientific article published on February 17, 2011

The metabolic syndrome in adult survivors of childhood cancer, a review

scientific article published on April 2010

The negative impact of being underweight and weight loss on survival of children with acute lymphoblastic leukemia

scientific article

The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.

scientific article published in September 2006

The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia

scientific article published on 15 July 2015

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

scientific article published on 25 February 2008

The role of constitutive activation of FMS-related tyrosine kinase-3 and NRas/KRas mutational status in infants with KMT2A-rearranged acute lymphoblastic leukemia

scientific article published on 24 August 2017

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia ⬇️

scientific article published on April 4, 2012

The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

scientific article published on 18 October 2013

The toxicity of very prolonged courses of PEGasparaginase or Erwinia asparaginase in relation to asparaginase activity, with a special focus on dyslipidemia

scientific article

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance

scientific article published on 5 December 2014

Towards targeted therapy for infant acute lymphoblastic leukaemia

scientific article

Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo

scientific article

Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors

scientific article published in October 2012

TropicALL study: Thromboprophylaxis in Children treated for Acute Lymphoblastic Leukemia with Low-molecular-weight heparin: a multicenter randomized controlled trial

scientific article

Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

scientific article

Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia.

scientific article published on 22 November 2016

Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia

scientific article published on 23 February 2006

Various components of the insulin-like growth factor system in tumor tissue, cerebrospinal fluid and peripheral blood of pediatric medulloblastoma and ependymoma patients

scientific article

Venous thromboembolism in a large cohort of children with acute lymphoblastic leukemia: Risk factors and effect on prognosis

Versican expression is an adverse prognostic factor in MLL-rearranged infant acute lymphoblastic leukaemia

scientific article published on 19 February 2016

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