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List of works by Patrick Emmet Duffy

A Malaria-Resistant Phenotype with Immunological Correlates in a Tanzanian Birth Cohort Exposed to Intense Malaria Transmission

scientific article published on May 2017

A Method for Producing Protein Nanoparticles with Applications in Vaccines

scientific article

A Plasma Survey Using 38 PfEMP1 Domains Reveals Frequent Recognition of the Plasmodium falciparum Antigen VAR2CSA among Young Tanzanian Children ⬇️

scientific article published on January 25, 2012

A high-throughput-sequence analysis infrastructure technology investigation framework for the evaluation of next-generation sequencing software.

scientific article published on 19 September 2011

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

scientific article published on 19 March 2021

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

scientific article published on 22 May 2017

A novel histological grading scheme for placental malaria applied in areas of high and low malaria transmission

scientific article

A primate model of severe malarial anaemia: a comparative pathogenesis study

scientific article published on 12 December 2019

ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells

scientific article published on 19 December 2017

Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.

scientific article published on 4 May 2017

Acute splenic infarction

scientific article published on August 2006

Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate

scientific article published on 16 January 2017

Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium

scientific article published on 30 November 2017

Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors

scholarly article published by Patrick E. Duffy in 2019

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An unusual presentation of placental malaria: a single persisting nidus of sequestered parasites

scientific article

Analysis of CSA-binding parasites and antiadhesion antibodies

scientific article published in January 2002

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria

scientific article published on 22 April 2020

Antibodies that inhibit Plasmodium falciparum adhesion to chondroitin sulfate A are associated with increased birth weight and the gestational age of newborns

scientific article

Antibodies to Escherichia coli-Expressed C-Terminal Domains of Plasmodium falciparum Variant Surface Antigen 2-Chondroitin Sulfate A (VAR2CSA) Inhibit Binding of CSA-Adherent Parasites to Placental Tissue ⬇️

scientific article published on January 14, 2013

Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection

scientific article (publication date: 23 May 2014)

Antibodies to PfsEGXP, An Early Gametocyte Enriched Phosphoprotein, Predict Decreased Plasmodium falciparum Gametocyte Density In Humans

article published in 2018

Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity ⬇️

scientific article published on January 1, 2011

Antibodies to rhoptry-associated membrane antigen predict resistance to Plasmodium falciparum

scientific article published on 29 July 2005

Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

scientific article

Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection

scientific article published on 6 February 2017

Antigen-presenting phagocytic cells ingest malaria parasites and increase HIV replication in a tumor necrosis factor α-dependent manner

scientific article

Are we losing artemisinin combination therapy already?

scientific article published in December 2005

Artemisinin combination therapies

scientific article

Bacteremia and malaria in Tanzanian children hospitalized for acute febrile illness

scientific article

CXC Ligand 9 Response to Malaria during Pregnancy Is Associated with Low-Birth-Weight Deliveries ⬇️

scientific article published on June 11, 2012

Catheter-directed thrombectomy and thrombolysis for symptomatic lower-extremity deep vein thrombosis: review of current interventional treatment strategies

scientific article published on September 1, 2010

Characterization of follicle and CL development in beef heifers using high resolution three-dimensional ultrasonography.

scientific article

Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model

scientific article

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

scientific article published on 15 November 2010

Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice

article

Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

scientific article published on 17 September 2016

Cloacal exstrophy: morbidity associated with abnormalities of the gastrointestinal tract and spine

scientific article published in August 2004

Comparisons between nulliparous heifers and cows as oocyte donors for embryo production in vitro

scientific article published in February 2005

Cord Blood Hepcidin: Cross-Sectional Correlates and Associations with Anemia, Malaria, and Mortality in a Tanzanian Birth Cohort Study

scientific article published on 27 June 2016

Corrigendum to “Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer” [Vaccine 30 (2012) 189–194]

scholarly article by Daming Zhu et al published May 2013 in Vaccine

Cross-Species Immune Recognition Between Plasmodium vivax Duffy Binding Protein Antibodies and the Plasmodium falciparum Surface Antigen VAR2CSA

scientific article published in 2019

Current challenges in Wilms' tumor management

scientific article

Cytokine profiles at birth predict malaria severity during infancy

scientific article

Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency

scientific article

Defending the Use of Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment for Malaria in Pregnancy: A Short-Sighted Strategy

scientific article published on 19 August 2015

Designing a VAR2CSA-based vaccine to prevent placental malaria

scientific article

Determination of protein concentration for protein-protein conjugates using ultraviolet absorption

scientific article

Development of a bivalent conjugate vaccine candidate against malaria transmission and typhoid fever.

scientific article published on 19 April 2018

Diagnosing malaria in pregnancy: an update ⬇️

scientific article published on October 1, 2012

Drug combinations for malaria: time to ACT?

scientific article

Drugs for malaria: something old, something new, something borrowed ⬇️

scientific article published on January 1, 2011

Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia ⬇️

scientific article published on December 29, 2011

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

scientific article

Effects of sex, parity, and sequence variation on seroreactivity to candidate pregnancy malaria vaccine antigens

scientific article published on 23 May 2007

Efficient extraction of vaccines formulated in aluminum hydroxide gel by including surfactants in the extraction buffer

scientific article published on 19 November 2011

Evaluation of Pregnancy Malaria Vaccine Candidates: The Binding Inhibition Assay

scientific article published on January 2015

Evaluation of patients with pain following total hip replacement.

scientific article published on January 2006

Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA.

scientific article published on 4 February 2008

Expanding the antimalarial toolkit: Targeting host-parasite interactions

scientific article

Fetal origins of malarial disease: cord blood cytokines as risk markers for pediatric severe malarial anemia

scientific article

Fetal responses during placental malaria modify the risk of low birth weight

scientific article published on 22 January 2008

Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection

scientific article published in July 2007

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines Against Malaria

scientific article published on 23 January 2017

HIV Nef protein causes endothelial dysfunction in porcine pulmonary arteries and human pulmonary artery endothelial cells

scientific article published on 04 March 2009

HIV Treatments Have Malaria Gametocyte Killing and Transmission Blocking Activity ⬇️

scientific article published on March 28, 2013

HIV nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages

scientific article

HIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivo

scientific article

Hemoglobin variants shape the distribution of malaria parasites in human populations and their transmission potential

scientific article published on 27 October 2017

Heterologous Infection of Pregnant Mice Induces Low Birth Weight and Modifies Offspring Susceptibility to Malaria

scientific article

Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

scientific article

High throughput functional assays of the variant antigen PfEMP1 reveal a single domain in the 3D7 Plasmodium falciparum genome that binds ICAM1 with high affinity and is targeted by naturally acquired neutralizing antibodies

scientific article

High-throughput screening platform identifies small molecules that prevent sequestration of Plasmodium falciparum-infected erythrocytes

scientific article

Host factors that modify Plasmodium falciparum adhesion to endothelial receptors

scientific article published on 24 October 2017

Hydrolytically degradable hyperbranched PEG-polyester adhesive with low swelling and robust mechanical properties

scientific article published on 8 September 2015

Hypertension and maternal-fetal conflict during placental malaria

scientific article (publication date: November 2006)

Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein

scientific article (publication date: 2016)

Identification of Protective B-Cell Epitopes within the Novel Malaria Vaccine Candidate Plasmodium falciparum Schizont Egress Antigen 1.

scientific article published on 3 May 2017

Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay

scientific article published on 23 January 2013

Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes

scientific article

Implications of Malaria On Iron Deficiency Control Strategies ⬇️

scientific article published on July 1, 2012

Incidence of Deflux® calcification masquerading as distal ureteric calculi on ultrasound

scientific article

Independent lineages of highly sulfadoxine-resistant Plasmodium falciparum haplotypes, eastern Africa

scientific article

Integrating Scientific English into Biological Sciences PhD Programs in Developing Countries: Strategies from Trainees and Mentor

scientific article published on 03 March 2019

Intermittent Preventive Treatment in Pregnant Women Is Associated with Increased Risk of Severe Malaria in Their Offspring ⬇️

scientific article published on February 25, 2013

Intermittent Treatment to Prevent Pregnancy Malaria Does Not Confer Benefit in an Area of Widespread Drug Resistance ⬇️

scientific article published on August 1, 2011

Intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine: the times they are a-changin'.

scientific article published on 19 June 2012

Investigation of Taper Failure in a Contemporary Metal-on-Metal Hip Arthroplasty System Through Examination of Unused and Explanted Prostheses

scientific article

Iron Deficiency Protects Against Severe Plasmodium falciparum Malaria and Death in Young Children ⬇️

scientific article published on February 21, 2012

Iron, anemia and hepcidin in malaria

scientific article

Kohn–Sham orbitals and orbital energies: fictitious constructs but good approximations all the same

Large screen approaches to identify novel malaria vaccine candidates

scientific article published on 28 September 2015

Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults

scholarly article published by Patrick E. Duffy in 2019

Malaria Infection and Gametocyte Carriage Rates in Preparation for Transmission Blocking Vaccine Trials in Bancoumana, Mali

scientific article published in July 2017

Malaria during Pregnancy

scientific article

Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060.

scientific article

Malaria in pregnancy: pathogenesis and immunity

scientific article published on February 2007

Malaria is related to decreased nutritional status among male adolescents and adults in the setting of intense perennial transmission

scientific article published on 15 July 2003

Malaria liver stage culture: in vitro veritas?

scientific article published in May 2006

Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes

scientific article

Malaria sporozoite proteome leaves a trail

scientific article published on 21 April 2009

Malaria vaccines since 2000: progress, priorities, products

scientific article published on 09 June 2020

Malaria vaccines: using models of immunity and functional genomics tools to accelerate the development of vaccines against Plasmodium falciparum

scientific article published in March 2005

Malaria: new diagnostics for an old problem.

scientific article published in September 2005

Malaria: progress, perils, and prospects for eradication

scientific article

Mass spectrometric analysis of Plasmodium falciparum erythrocyte membrane protein-1 variants expressed by placental malaria parasites

scientific article published in April 2004

Maternal Microchimerism Predicts Increased Infection but Decreased Disease due to Plasmodium falciparum During Early Childhood

scientific article published on 15 March 2017

Maternal immunization and malaria in pregnancy

scientific article

Maternal malaria and gravidity interact to modify infant susceptibility to malaria

scientific article

Maternal peripheral blood level of IL-10 as a marker for inflammatory placental malaria

scientific article

Maternally derived antibodies to Schizont Egress Antigen-1 and protection of infants from severe malaria

scientific article published on 01 May 2019

Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria

scientific article published on 3 December 2012

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

scientific article

NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children

scientific article

Natural selection of FLT1 alleles and their association with malaria resistance in utero

scholarly article

Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates

scientific article

New interventions for malaria: mining the human and parasite genomes

scientific article published on December 2007

Optimal mode for delivery of seasonal malaria chemoprevention in Ouelessebougou, Mali: A cluster randomized trial

scientific article published on 5 March 2018

Optimizing Direct Membrane and Direct Skin Feeding Assays for Plasmodium falciparum Transmission-Blocking Vaccine Trials in Bancoumana, Mali

scientific article published on 26 June 2017

P. falciparum enhances HIV replication in an experimental malaria challenge system

scientific article (publication date: 2012)

Parasite burden and severity of malaria in Tanzanian children

scientific article

Parasite burden and severity of malaria in Tanzanian children.

scientific article

Placental malaria vaccine candidate antigen VAR2CSA displays atypical domain architecture in some Plasmodium falciparum strains

scientific article published on 06 December 2019

Plant-produced transmission blocking Plasmodium falciparum Pfs25 subunit and VLP based vaccine candidates.

scientific article published on 15 October 2012

Plasma levels of apolipoprotein A1 in malaria-exposed primigravidae are associated with severe anemia

scientific article

Plasmodium falciparum adhesion in the placenta

scientific article

Plasmodium falciparum: chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta

scientific article

Plasmodium in the placenta: parasites, parity, protection, prevention and possibly preeclampsia

scientific article published on January 2007

Poly(ethylene glycol)-Based Hyperbranched Polymer from RAFT and Its Application as a Silver-Sulfadiazine-Loaded Antibacterial Hydrogel in Wound Care.

scientific article

Pre-erythrocytic malaria vaccines: identifying the targets ⬇️

scientific article published on October 1, 2012

Preparing for future efficacy trials of severe malaria vaccines

scientific article published on 25 February 2016

Prevalence of Asymptomatic Parasitemia and Gametocytemia in HIV-Infected Children on Differing Antiretroviral Therapy

scientific article

Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy

scientific article

Profound bias in interferon-gamma and interleukin-6 allele frequencies in western Kenya, where severe malarial anemia is common in children

scientific article published on 13 September 2002

Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

scientific article published on 12 October 2015

Protective human immunity as a vaccine discovery tool for falciparum malaria

scientific article published in August 2005

Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity

scientific article

Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials

scientific article published on March 2012

Recent advances in malaria research: new tools to understand an old enemy

scholarly article by Ana Paula Freitas do Rosario et al published August 2010 in Expert Review of Anti-infective Therapy

Red blood cells that do and red blood cells that don't: how to resist a persistent parasite

scientific article published on 7 February 2006

Regarding the consensus statement on 21-hydroxylase deficiency from the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology

scientific article published in July 2003

Response to Comment on "γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations".

scientific article published in March 2018

Response without shrinkage in bilateral Wilms tumor: significance of rhabdomyomatous histology

scientific article published in January 2002

Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains

scientific article

Reviews

Role of Activins in Hepcidin Regulation during Malaria

scientific article published on 11 September 2017

Rolling back a malaria epidemic in South Africa

scientific article

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

scientific article

Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge

scientific article

Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults

article

Seroepidemiology of helminths and the association with severe malaria among infants and young children in Tanzania

scientific article

Six genes are preferentially transcribed by the circulating and sequestered forms of Plasmodium falciparum parasites that infect pregnant women

scientific article

Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.

scientific article

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

scientific article published on 15 January 2021

Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins

scientific article published on 24 July 2020

Structure-function-immunogenicity studies of PfEMP1 domain DBL2βPF11_0521, a malaria parasite ligand for ICAM-1.

scientific article

Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children

scientific article

Supramolecular Fluorescent Nanoparticles Constructed via Multiple Non-Covalent Interactions for the Detection of Hydrogen Peroxide in Cancer Cells

scientific article

Systemic Inflammatory Response to Malaria During Pregnancy Is Associated With Pregnancy Loss and Preterm Delivery

scientific article published on 20 July 2017

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.

scientific article

Testicular outcome following laparoscopic second stage Fowler-Stephens orchidopexy

scientific article

The March Toward Malaria Vaccines

scientific article

The distinct proteome of placental malaria parasites

scientific article

The effect of antiretrovirals on Plasmodium falciparum liver stages ⬇️

scientific article published on June 19, 2013

The iron trap: iron, malaria and anemia at the mother-child interface

scientific article published on 12 March 2009

The march toward malaria vaccines

scientific article published on 28 August 2015

The relevance of non-human primate and rodent malaria models for humans

scientific article

Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge

scientific article published on 17 October 2016

Two DBLgamma subtypes are commonly expressed by placental isolates of Plasmodium falciparum

scientific article

Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies

scientific article

Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study

scientific article

VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies to Plasmodium falciparum Placental Malaria

scientific article published on 18 May 2016

VAR2CSA domains expressed in Escherichia coli induce cross-reactive antibodies to native protein

scientific article published in April 2008

VCF-Miner: GUI-based application for mining variants and annotations stored in VCF files

scientific article published on 25 July 2015

Valence orbital response to pseudorotation of tetrahydrofuran: a snapshot using dual space analysis

scientific article published in March 2008

What is the risk of urinary tract infection in children with antenatally presenting dilating vesico-ureteric reflux?

scientific article

XXV.—On the constitution of stearine

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