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List of works by Nguan Soon Tan

A STAT3-based gene signature stratifies glioma patients for targeted therapy

scientific article published on 09 August 2019

ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a

scientific article published on 07 July 2020

ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract

scientific article

An aPPARent Functional Consequence in Skeletal Muscle Physiology via Peroxisome Proliferator-Activated Receptors.

scientific article published on 10 May 2018

Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression.

scientific article published on 24 July 2017

Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice

scientific article (publication date: September 2014)

Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages

scientific article

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

scientific article

Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia

scientific article published on 04 June 2019

C-reactive protein collaborates with plasma lectins to boost immune response against bacteria

scientific article

CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms.

scientific article published on 15 April 2013

Comparative Study of Adipose-Derived Stem Cells From Abdomen and Breast

scientific article published in May 2016

Comparative study of adipose-derived stem cells and bone marrow-derived stem cells in similar microenvironmental conditions.

scientific article published on 19 September 2016

Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases.

scientific article

Critical roles of PPARβ/δ in keratinocyte response to inflammation ⬇️

scientific article published on December 15, 2001

Culturing fibroblasts in 3D human hair keratin hydrogels.

scientific article

Cutting Edge: Synchronization of IRF1, JunB, and C/EBPβ Activities during TLR3-TLR7 Cross-Talk Orchestrates Timely Cytokine Synergy in the Proinflammatory Response

scientific article published on 24 June 2015

Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice

scientific article published on 20 April 2020

Depletion of Gram-Positive Bacteria Impacts Hepatic Biological Functions During the Light Phase

scientific article published on 14 February 2019

Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex

scientific article (publication date: 14 November 2016)

Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment

scientific article

Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework

scientific article published on 20 June 2019

Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.

scientific article

Erratum to "The first contiguous estrogen receptor gene from a fish, Oreochromis aureus: evidence for multiple transcripts" [Mol. Cell. Endocrinol. 120 (1996) 186-188]

scientific article published on 01 October 1996

Evidence for the ancient origin of the NF-kappaB/IkappaB cascade: its archaic role in pathogen infection and immunity

scientific article

Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment

scientific article published on 30 March 2019

Fabrication and characterization of a novel crosslinked human keratin-alginate sponge

scientific article published on 25 April 2016

Fabrication and drug release study of double-layered microparticles of various sizes

scientific article published on 09 May 2012

Feeding Angptl4-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites

scientific article published on 15 April 2017

From flab to fab: transforming surgical waste into an effective bioactive coating material

scientific article

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer

scientific article published on 17 March 2021

High therapeutic index of factor C Sushi peptides: potent antimicrobials against Pseudomonas aeruginosa.

scientific article

Highly selective anti-cancer properties of ester functionalized enantiopure dinuclear gold(I)-diphosphine.

scientific article published on 19 May 2015

Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists

scientific article

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

scholarly article by Hwee Ying Lim et al published August 2018 in Immunity

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

scientific article published on 01 December 2018

Imparting electroactivity to polycaprolactone fibers with heparin-doped polypyrrole: Modulation of hemocompatibility and inflammatory responses

scientific article published on 14 May 2015

Insights into the Role of PPARβ/δ in NAFLD

scientific article published on 27 June 2018

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice

scientific article published on 20 June 2020

Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation

scientific article published on 05 March 2021

Materials Stiffness-Dependent Redox Metabolic Reprogramming of Mesenchymal Stem Cells for Secretome-Based Therapeutic Angiogenesis

scientific article published on 18 September 2019

Modular arrangement and secretion of a multidomain serine protease. Evidence for involvement of proline-rich region and N-glycans in the secretion pathway.

scientific article published on 27 June 2002

Molecular cloning and sequencing of the hormone-binding domain of Oreochromis aureus estrogen receptor gene.

scientific article published in January 1995

Multi-Drug-Loaded Microcapsules with Controlled Release for Management of Parkinson's Disease.

scientific article published on 2 June 2016

Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy.

scientific article published on 22 May 2017

Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multidrug-Resistant Bacteria

scientific article published on 13 October 2017

Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.

scientific article published on 03 September 2013

Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells ⬇️

scientific article published on March 21, 2013

Nuclear Hormone Receptors and Mouse Skin Homeostasis: Implication of PPARβ

scientific article published on 01 January 2000

Nuclear receptor peroxisome proliferator activated receptor (PPAR) β/δ in skin wound healing and cancer

scientific article published on April 2015

Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4

scientific article published on 05 December 2018

Overexpression of angiopoietin-like protein 4 protects against atherosclerosis development

scientific article

PPARalpha governs glycerol metabolism

scientific journal article

PPARβ/δ Agonism Upregulates Forkhead Box A2 to Reduce Inflammation in C2C12 Myoblasts and in Skeletal Muscle

scientific article published on 04 March 2020

Perylene-derived single-component organic nanoparticles with tunable emission: efficient anticancer drug carriers with real-time monitoring of drug release.

scientific article published on 16 May 2014

Polymer-Enriched 3D Graphene Foams for Biomedical Applications

scientific article published on 8 April 2015

ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response.

scientific article

Reactive oxygen species: a volatile driver of field cancerization and metastasis

scientific article published on 30 March 2019

Recellularization of decellularized adipose tissue-derived stem cells: role of the cell-secreted extracellular matrix in cellular differentiation.

scientific article published on 23 November 2017

Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.

scientific article published on 23 March 2006

Respiratory protein-generated reactive oxygen species as an antimicrobial strategy.

scientific article

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

scientific article

Selective Cooperation between Fatty Acid Binding Proteins and Peroxisome Proliferator-Activated Receptors in Regulating Transcription.

scientific article published in September 2002

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

scientific article published on 3 April 2018

Soft Material Approach to Induce Oxidative Stress in Mesenchymal Stem Cells for Functional Tissue Repair.

scientific article published on 9 September 2016

Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms ⬇️

scientific article published on 07 September 2011

Studying Wound Repair in the Mouse

scientific article

Surface modification of PVDF using non-mammalian sources of collagen for enhancement of endothelial cell functionality.

scientific article

Sustained-releasing hollow microparticles with dual-anticancer drugs elicit greater shrinkage of tumor spheroids.

scientific article

Synergistic effects of nuclear factors--GATA, VBP and ER in potentiating vitellogenin gene transcription

scientific article published on 01 October 1999

T-cell death following immune activation is mediated by mitochondria-localized SARM ⬇️

scientific article published on November 23, 2012

Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs

scientific article published on 20 October 2018

Targeting vascular leakage in lung inflammation.

scientific article published in August 2015

The G0/G1 switch gene 2 is a novel PPAR target gene.

scientific article

The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver.

scientific article published on 26 December 2006

The Potential of the FSP1cre-Pparb/d-/- Mouse Model for Studying Juvenile NAFLD

scientific article published on 15 October 2019

The anti-apoptotic role of PPARβ contributes to efficient skin wound healing

scientific article published on 01 June 2003

The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment

scientific article

The emerging role of Nrf2 in dermatotoxicology

scientific article

The first contiguous estrogen receptor gene from a fish, Oreochromis aureus: evidence for multiple transcripts.

scientific article published in July 1996

The hormone-binding domain of Oreochromis aureus estrogen receptor gene: homology comparison with other steroid binding receptors

scientific article published on 01 January 1995

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration

scientific article

The polyamine putrescine promotes human epidermal melanogenesis

scientific article published on 28 February 2020

Transcription regulatory signals in the 5' and 3' regions of Oreochromis aureus ER gene

scientific article published on 01 October 1996

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.

scientific article published on 22 September 2016

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