List of works - Roland Liblau

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

scientific article

A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11

scientific article

Antigen-driven interactions with dendritic cells and expansion of Foxp3+ regulatory T cells occur in the absence of inflammatory signals

scientific article published on 01 January 2008

Antigen-specific Treg impair CD8(+) T-cell priming by blocking early T-cell expansion.

scientific article published in February 2010

Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells

scientific article published on 01 August 2006

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

scientific article

CCR5 blockade for neuroinflammatory diseases--beyond control of HIV.

scientific article

CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model

scientific article

CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice.

scientific article published on October 2007

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.

scientific article

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

scientific article published on 18 December 2019

CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model.

scientific article published on 6 September 2016

Cell-mediated autoimmunity in paraneoplastic neurological syndromes with anti-Hu antibodies.

scientific article published in February 1999

Chromosome 17q22–q24 and multiple sclerosis genetic susceptibility

article

Chronic intravenous injections of antigen induce and maintain tolerance in T cell receptor-transgenic mice

scientific article published on 01 January 1999

Circulating follicular helper T cells exhibit reduced ICOS expression and impaired function in narcolepsy type 1 patients

scientific article published on 06 August 2018

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

scientific article

Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.

scientific article published on 15 July 2010

Cumulative Autoimmunity: T Cell Clones Recognizing Several Self-Epitopes Exhibit Enhanced Pathogenicity ⬇️

scientific article published on October 5, 2011

Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes.

scientific article published on August 2008

Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice.

scientific article published on June 2002

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.

scientific article published on January 2000

Delayed and separate costimulation in vitro supports the evidence of a transient "excited" state of CD8+ T cells during activation.

scientific article published in May 2000

Demyelinating diseases: from pathogenesis to repair strategies

scientific article published on 01 March 2001

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

scientific article

Disturbed regulatory T cell homeostasis in multiple sclerosis.

scientific article published on February 2010

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis

scientific article

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

scientific article published on 19 January 2018

EFNS task force report: a questionnaire-based survey on the service provision and quality assurance for determination of diagnostic autoantibody tests in European neuroimmunology centres. European Federation of Neurological Societies

scientific article published on 01 November 2000

EVER Proteins, Key Elements of the Natural Anti-Human Papillomavirus Barrier, Are Regulated upon T-Cell Activation ⬇️

scientific article published on June 28, 2012

Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes.

scientific article published in May 2003

Endothelial cells and lymphatics at the interface between the immune and central nervous systems: implications for multiple sclerosis

scientific article published on 18 March 2017

Enrichment of antigen-specific T lymphocytes by panning on immobilized MHC-peptide complexes

scientific article published on 01 November 1997

Enterocolitis induced by autoimmune targeting of enteric glial cells: a possible mechanism in Crohn's disease?

scientific article

Experimental autoimmune encephalomyelitis in IL-4-deficient mice

scientific article published on 01 May 1997

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells.

scientific article published on 28 January 2016

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.

scientific article published on 11 October 2016

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

scholarly article

From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development.

scientific article published on 28 August 2014

Gene transfer to the central nervous system by transplantation of cerebral endothelial cells.

scientific article published on February 1997

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

scientific article published on 12 October 2017

Hepatitis B vaccination and central nervous system demyelination: an immunological approach

scientific article published on 18 January 2005

High-dimensional single-cell analysis reveals the immune signature of narcolepsy.

scientific article

Human CD4 Expression at the Late Single-Positive Stage of Thymic Development Supports T Cell Maturation and Peripheral Export in CD4-Deficient Mice

article

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy

scientific article

Hypothalamic immunopathology in anti-Ma-associated diencephalitis with narcolepsy-cataplexy.

scientific article published on October 2013

IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration

scientific article published on 04 April 2019

Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation.

scientific article

Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

scientific article published on 01 February 1998

Immunopathogenesis of paraneoplastic neurological syndromes associated with anti-Hu antibodies: A beneficial antitumor immune response going awry

scientific article published on 10 December 2013

Immunotherapy of AD: Alum Demain?

scientific article published in January 2015

In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS.

scientific article published on 21 March 2016

Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives

scientific article published on 6 November 2017

Innate and adaptive immune responses in the CNS.

scientific article published on September 2015

Insulin modulates protease-activated receptor 2 signaling: implications for the innate immune response.

scientific article published on 29 January 2010

Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells.

scientific article published on August 2005

Invariant NKT cells regulate the CD8 T cell response during Theiler's virus infection

scientific article published on 30 January 2014

Ito cells are liver-resident antigen-presenting cells for activating T cell responses

scientific article

LF 15-0195 treatment protects against central nervous system autoimmunity by favoring the development of Foxp3-expressing regulatory CD4 T cells.

scientific article published on January 2006

Lack of association between human leukocyte antigens and the anti-Hu syndrome in patients with small-cell lung cancer

scientific article published on 01 February 1998

Localized proton magnetic resonance spectroscopy in relapsing remitting versus secondary progressive multiple sclerosis.

scientific article

Migration and pathogenicity of CD8 T cells in central nervous system diseases

scientific article

Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin

scientific article

Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out

scientific article

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.

scholarly article

Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self-antigen in mice

scientific article published on 23 June 2016

Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway

scientific article published on 12 June 2008

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment

scientific article published on 19 July 2019

Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells.

scientific article

Narcolepsy Type 1 as an Autoimmune Disorder: Evidence, and Implications for Pharmacological Treatment.

scientific article published on 22 September 2017

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

scientific article published on 22 October 2015

Neuromyelitis optica: a positive appraisal of seronegative cases.

scientific article

Neurons and T cells: Understanding this interaction for inflammatory neurological diseases

scientific article published on 08 September 2015

Neurons are MHC class I-dependent targets for CD8 T cells upon neurotropic viral infection

scientific article

Neurons as targets for T cells in the nervous system.

scientific article published on 13 March 2013

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

scientific article published on 13 March 2014

Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.

scientific article published on August 2006

Phosphorus-Based Dendrimer ABP Treats Neuroinflammation by Promoting IL-10-Producing CD4+ T Cells

scientific article published on 07 October 2015

Prediction of natalizumab anti-drug antibodies persistency.

scientific article published in January 2018

Prevention of diabetes in NOD mice by a mutated I-Ab transgene.

scientific article published in October 1998

Quality Assurance for Cerebrospinal Fluid Protein Analysis: International Consensus by an Internet-Based Group Discussion

scientific article published on 01 March 2003

Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.

scientific article

Recent advances in immunology in multiple sclerosis ⬇️

scientific article published on August 1, 1998

Recognition of a high affinity MHC class I-restricted epitope of myelin oligodendrocyte glycoprotein by CD8⁺ T cells derived from autoantigen-deficient mice.

scientific article

Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system.

scientific article published on June 2008

Relative diabetogenic properties of islet-specific Tc1 and Tc2 cells in immunocompetent hosts

scientific article published on 01 December 2000

Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons

scientific article published on 01 June 2019

Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis

scientific article

Role of astrocytes in antigen presentation and naive T-cell activation

scientific article published on 01 July 2000

Role of co-stimulation in CD8+ T cell activation.

scientific article published in May 1998

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

scientific article

Schwann cell transplantation and myelin repair of the CNS.

scientific article published on April 1997

Shared T cell receptor chains in blood memory CD4+ T cells of narcolepsy type 1 patients

scientific article published on 02 April 2019

Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells.

scientific article

Systemic Administration of Agonist Peptide Blocks the Progression of Spontaneous CD8-Mediated Autoimmune Diabetes in Transgenic Mice Without Bystander Damage

scientific article published on 01 July 2000

Systemic antigen in the treatment of T-cell-mediated autoimmune diseases ⬇️

scientific article published on December 1, 1997

Systemic autoimmune features and multiple sclerosis: a 5-year follow-up study

scientific article published on 01 April 1998

T cell receptor V beta 5 and V beta 17 clonal diversity in cerebrospinal fluid and peripheral blood lymphocytes of multiple sclerosis patients

scientific article published on 01 June 1998

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

scientific article published on January 1995

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.

scientific article

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

scientific article

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

scientific article published in July 1996

Therapeutic manipulation of iNKT cells in autoimmunity: modes of action and potential risks.

scientific article published in September 2004

Therapeutic potential of self-antigen-specific CD4+ CD25+ regulatory T cells selected in vitro from a polyclonal repertoire

scientific article published on 01 April 2006

Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8+ T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome

scientific article published on 15 January 2015

Thymus-Derived Regulatory T Cells Are Positively Selected on Natural Self-Antigen through Cognate Interactions of High Functional Avidity.

scientific article published on May 2016

Treatment of Progressive Multifocal Leukoencephalopathy with Nivolumab

scientific article published on 10 April 2019

Unique effects of KIT D816V in BaF3 cells: induction of cluster formation, histamine synthesis, and early mast cell differentiation antigens.

scientific article

Vaccine-associated inflammatory diseases of the central nervous system: from signals to causation.

scientific article

[An autoimmune basis for narcolepsy type 1?]

scientific article published on 01 March 2019

[Editorial]

scientific article published on 01 October 2014

List of works by Roland Liblau

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11

Antigen-driven interactions with dendritic cells and expansion of Foxp3+ regulatory T cells occur in the absence of inflammatory signals

Antigen-specific Treg impair CD8(+) T-cell priming by blocking early T-cell expansion.

Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

CCR5 blockade for neuroinflammatory diseases--beyond control of HIV.

CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model

CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice.

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model.

Cell-mediated autoimmunity in paraneoplastic neurological syndromes with anti-Hu antibodies.

Chromosome 17q22–q24 and multiple sclerosis genetic susceptibility

Chronic intravenous injections of antigen induce and maintain tolerance in T cell receptor-transgenic mice

Circulating follicular helper T cells exhibit reduced ICOS expression and impaired function in narcolepsy type 1 patients

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.

Cumulative Autoimmunity: T Cell Clones Recognizing Several Self-Epitopes Exhibit Enhanced Pathogenicity ⬇️

Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes.

Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice.

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.

Delayed and separate costimulation in vitro supports the evidence of a transient "excited" state of CD8+ T cells during activation.

Demyelinating diseases: from pathogenesis to repair strategies

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

Disturbed regulatory T cell homeostasis in multiple sclerosis.

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

EFNS task force report: a questionnaire-based survey on the service provision and quality assurance for determination of diagnostic autoantibody tests in European neuroimmunology centres. European Federation of Neurological Societies

EVER Proteins, Key Elements of the Natural Anti-Human Papillomavirus Barrier, Are Regulated upon T-Cell Activation ⬇️

Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes.

Endothelial cells and lymphatics at the interface between the immune and central nervous systems: implications for multiple sclerosis

Enrichment of antigen-specific T lymphocytes by panning on immobilized MHC-peptide complexes

Enterocolitis induced by autoimmune targeting of enteric glial cells: a possible mechanism in Crohn's disease?

Experimental autoimmune encephalomyelitis in IL-4-deficient mice

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells.

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development.

Gene transfer to the central nervous system by transplantation of cerebral endothelial cells.

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

Hepatitis B vaccination and central nervous system demyelination: an immunological approach

High-dimensional single-cell analysis reveals the immune signature of narcolepsy.

Human CD4 Expression at the Late Single-Positive Stage of Thymic Development Supports T Cell Maturation and Peripheral Export in CD4-Deficient Mice

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy

Hypothalamic immunopathology in anti-Ma-associated diencephalitis with narcolepsy-cataplexy.

IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration

Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation.

Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

Immunopathogenesis of paraneoplastic neurological syndromes associated with anti-Hu antibodies: A beneficial antitumor immune response going awry

Immunotherapy of AD: Alum Demain?

In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS.

Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives

Innate and adaptive immune responses in the CNS.

Insulin modulates protease-activated receptor 2 signaling: implications for the innate immune response.

Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells.

Invariant NKT cells regulate the CD8 T cell response during Theiler's virus infection

Ito cells are liver-resident antigen-presenting cells for activating T cell responses

LF 15-0195 treatment protects against central nervous system autoimmunity by favoring the development of Foxp3-expressing regulatory CD4 T cells.

Lack of association between human leukocyte antigens and the anti-Hu syndrome in patients with small-cell lung cancer

Localized proton magnetic resonance spectroscopy in relapsing remitting versus secondary progressive multiple sclerosis.

Migration and pathogenicity of CD8 T cells in central nervous system diseases

Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin

Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.

Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self-antigen in mice

Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment

Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells.

Narcolepsy Type 1 as an Autoimmune Disorder: Evidence, and Implications for Pharmacological Treatment.

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

Neuromyelitis optica: a positive appraisal of seronegative cases.

Neurons and T cells: Understanding this interaction for inflammatory neurological diseases

Neurons are MHC class I-dependent targets for CD8 T cells upon neurotropic viral infection

Neurons as targets for T cells in the nervous system.

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.

Phosphorus-Based Dendrimer ABP Treats Neuroinflammation by Promoting IL-10-Producing CD4+ T Cells