List of works - Y Yang

1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists.

scientific article published on 26 October 2010

A novel adipokine CTRP1 stimulates aldosterone production

scientific article

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

scientific article published on 18 July 2006

Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production.

scientific article

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

scientific article published on 27 December 2007

Adiponectin is a negative regulator of NK cell cytotoxicity.

scientific article

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

scientific article published on 14 April 2009

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

scientific article published on 30 March 2018

Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase

scientific article published on 01 July 2016

Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. ⬇️

scientific article published in August 2008

Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway.

scientific article

Antiobesity effects of a sulfur compound thiacremonone mediated via down-regulation of serum triglyceride and glucose levels and lipid accumulation in the liver of db/db mice.

scientific article published on 6 January 2012

Apolipoprotein A-I induces IL-10 and PGE2 production in human monocytes and inhibits dendritic cell differentiation and maturation.

scientific article published on 21 October 2005

Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g)

scientific article

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.

scientific article

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

scientific article

C1q/TNF-α-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions

scientific article published on 01 August 2018

CTRP1 protects against diet-induced hyperglycemia by enhancing glycolysis and fatty acid oxidation

scientific article published on 28 August 2015

Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity.

scientific article

Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g).

scientific article published on 27 September 2013

Circulating CTRP1 Levels in Type 2 Diabetes and Their Association with FGF21

scientific article published on 23 May 2016

Cloning and characterization of bovine interleukin-32 beta isoform.

scientific article published on 7 May 2010

Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells

scientific journal article

Combined Treatment of Herbal Mixture Extract H9 with Trastuzumab Enhances Anti-tumor Growth Effect

scientific article

Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells.

scientific article

Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

scientific article published on 19 December 2013

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

scientific article published on 23 August 2014

Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases

scientific article

Development of suspension cell culture model to mimic circulating tumor cells

scientific article published on 7 December 2017

Dexamethasone reverses TGF-beta-mediated inhibition of primary rat preadipocyte differentiation

scientific journal article

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

scientific article published on 28 April 2014

Effects of acupuncture on chronic corticosterone-induced depression-like behavior and expression of neuropeptide Y in the rats.

scientific article published on 4 February 2009

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

scientific article published on 03 June 2009

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

scientific article

Estradiol enhances CIP2A expression by the activation of p70 S6 kinase.

scientific article published on 30 January 2014

Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5.

scientific article published on 15 September 2017

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

scientific article

Hypoxia-induced IL-32β increases glycolysis in breast cancer cells.

scientific article published on 6 November 2014

IFITM6 expression is increased in macrophages of tumor-bearing mice.

scientific article published on 10 December 2010

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

scientific article

IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells.

scientific article

Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.

scientific article published on 2 October 2009

Identification of differentially-expressed genes by DNA methylation in cervical cancer.

scientific article

Increase in CIP2A expression is associated with doxorubicin resistance.

scientific article published on 18 January 2011

Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes.

scientific article

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

scientific article published on 24 March 2016

Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function

scientific article published on 6 September 2016

Interleukin 4-induced proliferation in normal human keratinocytes is associated with c-myc gene expression and inhibited by genistein

scientific article published on 01 September 1996

Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.

scientific article

Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase Cɛ-dependent sumoylation

scientific article

Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway.

scientific article published on 10 October 2013

Interleukin-32δ interacts with IL-32β and inhibits IL-32β-mediated IL-10 production

scientific article

KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus.

scientific article published on 02 August 2011

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer.

scientific article

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMP kinase activation

scientific article published on 28 January 2019

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

scientific article

Luteolin supplementation modulates mammary tumor growth in C3H mice fed diet with high- and low-fat content.

scientific article published on 27 September 2013

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.

scientific article published on 6 February 2008

MiR-146a Regulates Migration and Invasion by Targeting NRP2 in Circulating-Tumor Cell Mimicking Suspension Cells

scientific article published on 30 December 2020

Molecular Mechanisms and Emerging Therapeutics for Osteoporosis

scientific article published on 15 October 2020

Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase

scientific article

N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial-mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling

scientific article published on 19 August 2014

NDRG2 controls COX-2/PGE₂-mediated breast cancer cell migration and invasion.

scientific article

NDRG2 gene expression in B16F10 melanoma cells restrains melanogenesis via inhibition of Mitf expression.

scientific article

Neuronatin Is Associated with an Anti-Inflammatory Role in the White Adipose Tissue.

scientific article published on 24 March 2017

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

scientific article published on April 2015

Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.

scientific article published on 28 February 2018

Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha.

scientific article published in January 2009

Osteopontin promotes the development of natural killer cells from hematopoietic stem cells.

scientific article published on 5 June 2008

Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

scientific article published on 07 June 2016

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

scientific article published on 13 January 2015

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

scientific article published on 14 September 2007

SUMOylation of RORalpha potentiates transcriptional activation function.

scientific article published on 28 November 2008

Serum BAFF expression in patients with myasthenia gravis.

scientific article published on 30 June 2008

Shikonin inhibits adipogenesis by modulation of the WNT/β-catenin pathway.

scientific article published on 10 December 2010

Silent mating-type information regulation 2 homolog 1 overexpression is an important strategy for the survival of adapted suspension tumor cells

scientific article published on 11 August 2019

Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9

scientific article published in Scientific Reports

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

scientific article published on 21 August 2015

The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.

scientific article published on 15 July 2014

The biflavonoid amentoflavone induces apoptosis via suppressing E7 expression, cell cycle arrest at sub-G₁ phase, and mitochondria-emanated intrinsic pathways in human cervical cancer cells.

scientific article published on 11 June 2011

The expression of BAFF in the muscles of patients with dermatomyositis.

scientific article published on 09 May 2012

The functional roles of PML nuclear bodies in genome maintenance.

scientific article

The interferon-inducible 9-27 gene modulates the susceptibility to natural killer cells and the invasiveness of gastric cancer cells.

scientific article

The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

scientific article

Thiacremonone, a sulfur compound isolated from garlic, attenuates lipid accumulation partially mediated via AMPK activation in 3T3-L1 adipocytes.

scientific article published on 8 March 2012

Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.

scientific article

UVB-induced interleukin-18 production is downregulated by tannic acids in human HaCaT keratinocytes.

scientific article published on August 2006

Upregulation and secretion of macrophage inhibitory cytokine-1 (MIC-1) in gastric cancers.

scientific article

VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

scientific article (publication date: 26 June 2003)

Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function

scientific journal article

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells.

scientific article published on 17 July 2017

List of works by Y Yang

1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists.

A novel adipokine CTRP1 stimulates aldosterone production

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production.

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

Adiponectin is a negative regulator of NK cell cytotoxicity.

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase

Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. ⬇️

Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway.

Antiobesity effects of a sulfur compound thiacremonone mediated via down-regulation of serum triglyceride and glucose levels and lipid accumulation in the liver of db/db mice.

Apolipoprotein A-I induces IL-10 and PGE2 production in human monocytes and inhibits dendritic cell differentiation and maturation.

Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g)

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

C1q/TNF-α-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions

CTRP1 protects against diet-induced hyperglycemia by enhancing glycolysis and fatty acid oxidation

Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity.

Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g).

Circulating CTRP1 Levels in Type 2 Diabetes and Their Association with FGF21

Cloning and characterization of bovine interleukin-32 beta isoform.

Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells

Combined Treatment of Herbal Mixture Extract H9 with Trastuzumab Enhances Anti-tumor Growth Effect

Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells.

Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases

Development of suspension cell culture model to mimic circulating tumor cells

Dexamethasone reverses TGF-beta-mediated inhibition of primary rat preadipocyte differentiation

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

Effects of acupuncture on chronic corticosterone-induced depression-like behavior and expression of neuropeptide Y in the rats.

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

Estradiol enhances CIP2A expression by the activation of p70 S6 kinase.

Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5.

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

Hypoxia-induced IL-32β increases glycolysis in breast cancer cells.

IFITM6 expression is increased in macrophages of tumor-bearing mice.

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells.

Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.

Identification of differentially-expressed genes by DNA methylation in cervical cancer.

Increase in CIP2A expression is associated with doxorubicin resistance.

Inhibition of osteoclast differentiation by overexpression of NDRG2 in monocytes.

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function

Interleukin 4-induced proliferation in normal human keratinocytes is associated with c-myc gene expression and inhibited by genistein

Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.

Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase Cɛ-dependent sumoylation

Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway.

Interleukin-32δ interacts with IL-32β and inhibits IL-32β-mediated IL-10 production

KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus.

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer.

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMP kinase activation

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

Luteolin supplementation modulates mammary tumor growth in C3H mice fed diet with high- and low-fat content.

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.

MiR-146a Regulates Migration and Invasion by Targeting NRP2 in Circulating-Tumor Cell Mimicking Suspension Cells

Molecular Mechanisms and Emerging Therapeutics for Osteoporosis

Molecular cloning and chromosomal localization of a human gene homologous to the murine R-PTP-kappa, a receptor-type protein tyrosine phosphatase

N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial-mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling

NDRG2 controls COX-2/PGE₂-mediated breast cancer cell migration and invasion.

NDRG2 gene expression in B16F10 melanoma cells restrains melanogenesis via inhibition of Mitf expression.

Neuronatin Is Associated with an Anti-Inflammatory Role in the White Adipose Tissue.

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.

Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha.

Osteopontin promotes the development of natural killer cells from hematopoietic stem cells.

Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

SUMOylation of RORalpha potentiates transcriptional activation function.

Serum BAFF expression in patients with myasthenia gravis.

Shikonin inhibits adipogenesis by modulation of the WNT/β-catenin pathway.

Silent mating-type information regulation 2 homolog 1 overexpression is an important strategy for the survival of adapted suspension tumor cells

Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.