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List of works by Francoise Degoul

'Aberrant localisation of Annexin A1 is associated with metastatic outcome in thin melanomas'

scientific article published on 23 October 2019

(123)I-BZA2 as a melanin-targeted radiotracer for the identification of melanoma metastases: results and perspectives of a multicenter phase III clinical trial.

scientific article published on 21 November 2013

A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.

scientific article published on January 1998

A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.

scientific article published on 4 July 2016

A near homoplasmic T8993G mtDNA mutation in a patient with atypic Leigh syndrome not present in the mother's tissues.

scientific article published in March 1997

Alkylation of prohibitin by cyclohexylphenyl-chloroethyl urea on an aspartyl residue is associated with cell cycle G(1) arrest in B16 cells.

scientific article

Annexin A1 in primary tumors promotes melanoma dissemination.

scientific article published on 06 July 2014

Annexin A1 localization and its relevance to cancer

scientific article

Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models

scientific article published on 2 November 2017

Antibody Pretargeting Based on Bioorthogonal Click Chemistry for Cancer Imaging and Targeted Radionuclide Therapy

scientific article published on 06 January 2020

Antineoplastic potency of arylchloroethylurea derivatives in murine colon carcinoma.

scientific article published on November 2004

B16 melanoma secretomes and in vitro invasiveness: syntenin as an invasion modulator.

scientific article published in April 2010

CPOP: An open source C++ cell POPulation modeler for radiation biology applications

scientific article published in 2021

Characterization of pro-invasive mechanisms and N-terminal cleavage of ANXA1 in melanoma.

scientific article

Characterization of the Covalent Binding ofN-Phenyl-N′-(2-chloroethyl)ureas to β-Tubulin: Importance of Glu198 in Microtubule Stability

scientific article published on October 26, 2010

Clinical, biochemical, and molecular analysis of a maternally inherited case of Leigh syndrome (MILS) associated with the mtDNA T8993G point mutation

scientific article published on 01 January 1995

Determination of eumelanin and pheomelanin in melanomas using solid-phase extraction and high performance liquid chromatography-diode array detection (HPLC-DAD) analysis

scientific article published on 11 March 2019

Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing.

scientific article published on 13 July 2017

Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma

scientific article published on 13 July 2017

Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.

scientific article published on 16 June 2012

Evaluation of two (125)I-radiolabeled acridine derivatives for Auger-electron radionuclide therapy of melanoma.

scientific article published on 2 April 2014

Genetic dimorphism in superoxide dismutase and susceptibility to alcoholic cirrhosis, hepatocellular carcinoma, and death.

scientific article

Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy

scientific article published on 23 May 2020

In vivo efficacy of melanoma internal radionuclide therapy with a 131I-labelled melanin-targeting heteroarylcarboxamide molecule.

scientific article

Internal dosimetry through GATE simulations of preclinical radiotherapy using a melanin-targeting ligand.

scientific article published on 8 April 2014

Intrafamilial heterogeneous clinical presentation of the mitochondrial 3243 MELAS mutation; molecular investigations among four generations

scientific article published on 01 December 1995

Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.

scientific article published on March 2011

Kearns-Sayre syndrome with sideroblastic anemia: molecular investigations

scientific article published on August 1, 1992

Merrf family with 8344 mutation in tRNA (lys). Evidence of a mitochondrial vasculopathy in muscle biopsies

scientific article published on 01 September 1993

MnSOD overexpression prevents liver mitochondrial DNA depletion after an alcohol binge but worsens this effect after prolonged alcohol consumption in mice.

scientific article published on January 2010

Myo-leukoencephalopathy in twins: study of 3243-myopathy, encephalopathy, lactic acidosis, and strokelike episodes mitochondrial DNA mutation

scientific article published on 01 March 1994

N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.

scientific article published on 8 May 2007

Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept

scientific article published on 19 September 2019

Proteoglycan-targeting applied to hypoxia-activated prodrug therapy in chondrosarcoma: first proof-of-concept.

scientific article published on 27 September 2017

Proteoglycans as Target for an Innovative Therapeutic Approach in Chondrosarcoma: Preclinical Proof of Concept.

scientific article published on 29 August 2016

Radiation dosimetry of [131 I]ICF01012 in rabbits: Application to targeted radionuclide therapy for human melanoma treatment

scientific article published on 24 September 2018

Small rigid platforms functionalization with quaternary ammonium: targeting extracellular matrix of chondrosarcoma.

scientific article

Synthesis, radiolabeling and preliminary in vivo evaluation of multimodal radiotracers for PET imaging and targeted radionuclide therapy of pigmented melanoma

scientific article published on 21 January 2015

TIP60 Inhibitor TH1834 Reduces Breast Cancer Progression in Xenografts in Mice

scientific article published on 01 September 2019

TIP60: an actor in acetylation of H3K4 and tumor development in breast cancer

scientific article published on 16 October 2018

Targeted Radionuclide Therapy Decreases Melanoma Lung Invasion by Modifying Epithelial-Mesenchymal Transition-Like Mechanisms

scientific article published on 14 August 2019

Targeting DNA repair by coDbait enhances melanoma targeted radionuclide therapy

scientific article published on 12 February 2016

Targeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029

scientific article published on 03 February 2019

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

scientific article

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.

scientific article published on 04 February 2017

The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability.

scientific article

Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy

scientific article published on 14 December 2016

Third International Congress on Human Mitochondrial Pathology (Euromit III): towards a better understanding of energy metabolism disorders

scientific article published on 01 May 1996

Tspan8 Drives Melanoma Dermal Invasion by Promoting ProMMP-9 Activation and Basement Membrane Proteolysis in a Keratinocyte-Dependent Manner

scientific article published on 21 May 2020

Uneven distribution of mitochondrial DNA mutation in MERRF dizygotic twins

scientific article published on July 1, 1992

[Ageing, alcohol and mitochondria]

scientific article published on 01 March 2000

[¹²³I]ICF01012 melanoma imaging and [¹³¹I]ICF01012 dosimetry allow adapted internal targeted radiotherapy in preclinical melanoma models.

scientific article