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List of works by Paola Sebastiani

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

scientific article

A Bayesian dynamic model for influenza surveillance

A Bayesian dynamic model for influenza surveillance.

scientific article

A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells

scientific article

A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants

scientific article published on 21 December 2022

A SERUM PROTEIN SIGNATURE OF APOE GENOTYPES IN CENTENARIANS

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

A Simple Strategy for Identifying Conserved Features across Non-independent Omics Studies

scientific article published on 23 July 2024

A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia

scientific article published on 7 August 2016

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment

scientific article

A family longevity selection score: ranking sibships by their longevity, size, and availability for study.

scientific article

A gene-diet interaction-based score predicts response to dietary fat in the Women's Health Initiative

scientific article published on 01 April 2020

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia

scientific article

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

scientific article

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

A metabolomic signature of the APOE2 allele

scientific article published in February 2023

A network model to predict the risk of death in sickle cell disease

scientific article

A note on D-optimal designs for a logistic regression model

scholarly article

A novel healthy blood pressure phenotype in the Long Life Family Study.

scientific article

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity

scientific article published on 30 January 2019

A phased SNP-based classification of sickle cell anemia HBB haplotypes

scientific article published on 11 August 2017

A prediction model for lung cancer diagnosis that integrates genomic and clinical features

scientific article

A serum protein signature of APOE genotypes in centenarians

scientific article published on 05 August 2019

APOE Alleles and Extreme Human Longevity

scientific article published on 01 January 2019

Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.

scientific article published on 26 October 2016

Age validation in the long life family study through a linkage to early-life census records

scientific article published on 23 May 2013

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

article

Altered Inflammatory Gene Expression Occurs In Peripheral Blood Mononuclear Cells Of Sickle Cell Disease Patients With An Elevated Tricuspid Regurgitant Jet Velocity And Pulmonary Hypertension

article

An efficient technique for Bayesian modeling of family data using the BUGS software

scientific article

Ancestry of African Americans with sickle cell disease

scientific article

Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study

scientific article published on 17 November 2020

Association between wind speed and the occurrence of sickle cell acute painful episodes: results of a case-crossover study

scientific article

Association of Genetic Polymorphisms In NEDD4L With Pulmonary Hypertension Of Sickle Cell Disease

Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis

scientific article published on 22 March 2005

Assortative Mating by Ethnicity in Longevous Families

scientific article

BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.

scientific article

BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies

scientific article published on 8 August 2008

BCL2L1 is associated with γ-globin gene expression

scientific article published on 01 October 2019

BET bromodomain inhibition as a novel strategy for reactivation of HIV-1

scientific article

Bayesian Clustering by Dynamics

Bayesian Clustering of Gene Expression Dynamics

article

Bayesian Clustering of Gene Expression Dynamics: An Application

article

Bayesian Correction for SNP Ascertainment Bias

article

Bayesian Inference with Missing Data Using Bound and Collapse

article by Paola Sebastiani & Marco Ramoni published December 2000 in Journal of Computational and Graphical Statistics

Bayesian Inference with Missing Data Using Bound and Collapse

scientific article published in December 2000

Bayesian Methods

Bayesian Polynomial Regression Models to Fit Multiple Genetic Models for Quantitative Traits ⬇️

scientific article published on March 2015

Bayesian Selection of Decomposable Models With Incomplete Data

Bayesian analysis of comparative microarray experiments by model averaging

article

Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks.

scientific article

Bayesian estimates of linkage disequilibrium

scientific article

Bayesian methods for multivariate modeling of pleiotropic SNP associations and genetic risk prediction.

scientific article

Biomarker signatures of aging

scientific article

Biomarker signatures of sickle cell disease severity

scientific article published on 16 May 2018

Book reviews

Building chromosome-wide LD maps

scientific article

Burden of disease variants in participants of the Long Life Family Study

scientific article

CLONAL HEMATOPOIESIS IN A CENTENARIAN COHORT

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

CaDrA: A Computational Framework for Performing Candidate Driver Analyses Using Genomic Features

scientific article published on 19 February 2019

CaDrA: A computational framework for performing candidate driver analyses using binary genomic features

Can we use linear Gaussian networks to model dynamic interactions among genes? Results from a simulation study

article

Cancer Diagnosis, Polygenic Risk, and Longevity-Associated Variants

scientific article published on 22 September 2020

Cluster analysis of gene expression dynamics

scientific article

Clustering by genetic ancestry using genome-wide SNP data

scientific article

Complex Genetic Models

Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity

scientific article published on 5 July 2016

Conditional clustering of temporal expression profiles

scientific article

Correction: RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans.

scientific article published on 15 December 2009

D-optimal designs for generalised linear models with variance proportional to the square of the mean

DNA methylation modules associate with incident cardiovascular disease and cumulative risk factor exposure

scientific article published on 15 October 2019

Designing Microarray Experiments

Detection of Significant Groups in Hierarchical Clustering by Resampling

scientific article

Differential gene expression in pulmonary artery endothelial cells exposed to sickle cell plasma

scientific article published in March 2005

Discovering Dynamics Using Bayesian Clustering

Disentangling the roles of disability and morbidity in survival to exceptional old age.

scientific article

Early dysregulation of cell adhesion and extracellular matrix pathways in breast cancer progression

scientific article published on 21 August 2009

Educating translational researchers in research informatics principles and methods: an evaluation of a model online course and plans for its dissemination

scientific article published on 18 March 2013

Effect of longevity genetic variants on the molecular aging rate

scientific article published on 04 May 2021

Effecting the culture: Impact of changing urinalysis with reflex to culture criteria on culture rates and outcomes

scientific article published on 4 August 2022

Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.

scientific article

Efforts to Characterize Host Response to HIV-1 Infection

article

Epigenomic Assessment of Cardiovascular Disease Risk and Interactions With Traditional Risk Metrics

scientific article published on 20 April 2020

Estimating the Relative Probability of Direct Transmission between Infectious Disease Patients

scientific article published on 27 April 2019

Estimating the relative probability of direct transmission between infectious disease patients

scientific article published on 24 March 2020

Evaluation of an ensemble of genetic models for prediction of a quantitative trait

scientific article

Evidence for cross-regulated cytokine response in human peripheral blood mononuclear cells exposed to whole gonococcal bacteria in vitro

article

Evolution and challenges in the design of computational systems for triage assistance.

scientific article

Experimental designs for mean and variance estimation in variance components models

Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer

scientific article

Extended maternal age at birth of last child and women's longevity in the Long Life Family Study

scientific article

Factors affecting automated syndromic surveillance

scientific article

Familial Risk for Exceptional Longevity ⬇️

scientific article published on 7 October 2015

Families Enriched for Exceptional Longevity also have Increased Health-Span: Findings from the Long Life Family Study

scientific article published on 30 September 2013

Fetal hemoglobin in sickle cell anemia

scientific article

Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations

scientific article

Fetal hemoglobin in sickle cell anemia: a glass half full?

scientific article published on 12 November 2013

Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype

scientific article

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

scientific article

Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans.

scientific article published on 3 December 2011

Fetal hemoglobin per erythrocyte ( HbF /F‐cell) after gene therapy for sickle cell anemia

scientific article published on 30 November 2022

First-order optimal designs for non-linear models

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants

scientific article published on 15 March 2017

GENOME-WIDE ASSOCIATION STUDY OF EXTREME HUMAN LONGEVITY DISCOVERS UNCOMMON LONGEVITY VARIANTS

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

scientific article

Genetic associations with age of menopause in familial longevity

scientific article published on 01 October 2019

Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemia

scientific article published on 13 June 2017

Genetic determinants of haemolysis in sickle cell anaemia

scientific article

Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia

scientific article

Genetic modifiers of sickle cell disease

scientific article

Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study

scientific article

Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease

scientific article

Genetic signatures of exceptional longevity in humans

scientific article (publication date: 2012)

Genetic studies of fetal hemoglobin in the Arab-Indian haplotype sickle cell-β0thalassemia

scientific article published on 02 May 2013

Genome-wide association studies and the genetic dissection of complex traits

scientific article published on August 2009

Genome-wide association study of personality traits in the long life family study

scientific article published on 8 May 2013

HIV-1 burden influences host response to co-infection with Neisseria gonorrhoeae in vitro

article

Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

scientific article published on 23 September 2019

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

scientific article

Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span

scientific article published on 4 January 2012

Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism

scientific article published on 22 July 2019

Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia

scientific article published on 28 April 2016

Human Genome Project

Human longevity and common variations in the LMNA gene: a meta-analysis

scientific article

Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease

scientific article

Identification Of Lung Disease-Associated Novel Transcripts And Alternative Splicing By RNA-Sequencing

Identification of candidate cancer drivers by integrative Epi-DNA and Gene Expression (iEDGE) data analysis

scientific article published on 15 November 2019

Identification of serum biomarkers for aging and anabolic response

scientific article

Identifying Novel Transcripts And Alternative Splicing Associated With The ILD And COPD Lung Transcriptome Using MRNA-Seq

scholarly article published May 2011

Impact of provider-selected indication requirement on urine test utilization and positivity

scientific article published in 2022

Implementing syndromic surveillance: a practical guide informed by the early experience.

scientific article

Imputation of missing genotypes: an empirical evaluation of IMPUTE.

scientific article

Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".

scientific article published on 26 March 2015

Induction of Graphical Models from Incomplete Samples

Inflammatory signatures distinguish metabolic health in African American women with obesity.

scientific article published on 8 May 2018

Intelligent Data Analysis of Human Genetic Data

LONG-LIVED INDIVIDUALS PRESENTING WITH LARGE BREAST AND COLON TUMORS HAVE A LOWER RISK OF CONCURRENT METASTASIS

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Learning Bayesian Networks from Correlated Data

scientific article

Leg ulcers in sickle cell disease

scientific article

Limitations and risks of meta-analyses of longevity studies

scientific article

Manual and Automated Procedures for Compiling a Very Large Sample of Centenarian Pedigrees

scientific article published on 27 September 2018

Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans

scientific article published on August 2012

Meta‐analysis of genetic variants associated with human exceptional longevity

scientific article

Minimal haplotype tagging

scientific article published on 4 August 2003

Morphological and functional changes in the retinotectal system of the pigeon during the early posthatching period

scientific article published in February 1987

Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing.

scientific article published in October 2012

NEUROPROTECTIVE EFFECT OF APOE2: EVIDENCE AND IMPLICATION FOR COGNITIVE AGING

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Naïve Bayesian Classifier and Genetic Risk Score for Genetic Risk Prediction of a Categorical Trait: Not so Different after all!

scientific article published on 29 February 2012

Normative selection of Bayesian networks

Novel loci and pathways significantly associated with longevity

scientific article published on 25 February 2016

On the Derivatives of Matrix Powers

Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease

scientific article published on 27 March 2016

Patterns of multi-domain cognitive aging in participants of the Long Life Family Study

scientific article published on 08 June 2020

Personality factors in the Long Life Family Study

scientific article

Personality traits of centenarians' offspring

scientific article

PleioGRiP: genetic risk prediction with pleiotropy

scientific article

PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects

scientific article published on 01 September 2019

Population dynamics ofDaphnia galeataSars andBosmina longirostrisMuell in Lake Trasimeno, Italy

article

Prediction models that include genetic data

scientific article published on February 2010

Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models

scientific article published on March 2014

Premature expression of a muscle fibrosis axis in chronic HIV infection

scientific article

Prenatal buprenorphine versus methadone exposure and neonatal outcomes: systematic review and meta-analysis

scientific article

Prevalence, Incidence, and Risk Factors for Overall, Physical, and Cognitive Independence Among Those From Exceptionally Long-Lived Families: The Long Life Family Study

scientific article published on 14 May 2019

Profiling your customers using Bayesian networks

Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

scientific article published on 29 January 2021

Purpose in Life Among Centenarian Offspring.

scientific article published on 7 March 2018

REDUCED COGNITIVE DECLINE WITH THE APOE ε2/ε2 GENOTYPE IN THE LONG LIFE FAMILY STUDY AND NEW ENGLAND CENTENARIAN STUDY

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

RETRACTED: Genetic signatures of exceptional longevity in humans

retracted scientific article

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans

scientific article

Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring

scientific article published on 01 January 2019

Relationship between poor physical function, inflammatory markers, and comorbidities in HIV-infected women on antiretroviral therapy

scientific article

Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women

scientific article

Retraction

scientific article published on 01 July 2011

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression

scientific article published on January 2007

Robust Bayes classifiers

Robust Bayesian classification

Robust outcome prediction for intensive-care patients.

scientific article published on March 2001

Robust transmission/disequilibrium test for incomplete family genotypes

scientific article

Sequence Learning via Bayesian Clustering by Dynamics

article

Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1

scientific article

Sex Differences in Genetic Associations With Longevity

Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign.

scientific article

Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway

scientific article

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

scientific article

Single nucleotide polymorphisms associated with sporadic brain arteriovenous malformations: where do we stand?

scientific article published on 13 September 2012

Statistical Challenges in Functional Genomics

Telomere length is longer in women with late maternal age.

scientific article published on 5 December 2016

Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures

scientific article published on 26 May 2015

The comparative safety of buprenorphine versus methadone in pregnancy-what about confounding?

scientific article published on December 2016

The genetics of extreme longevity: lessons from the new England centenarian study

scientific article

The genetics of hemoglobin A2 regulation in sickle cell anemia

scientific article

The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy

scientific article published on 28 April 2009

The use of exogenous knowledge to learn Bayesian Networks from incomplete databases

Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes

scientific article

Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss

scientific article published on 17 April 2007

Upper Airway Gene Expression As A Biomarker Of Active And Secondhand Smoke Exposure

article

Uroplakin 3a+ Cells Are a Distinctive Population of Epithelial Progenitors that Contribute to Airway Maintenance and Post-injury Repair

scientific article published in April 2017

Using cure models to estimate the serial interval of tuberculosis with limited follow-up

scientific article published on 27 May 2020

Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia

article

Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities

scientific article published on 01 November 2019

Whole genome sequences of a male and female supercentenarian, ages greater than 114 years

scientific article published on January 2011

design

article by Paola Sebastiani & A. Philip Dawid published March 1999 in Annals of Statistics

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