List of works - Helen Christian

Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.

scientific article

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

scientific article published in October 2002

Activation of the HPA axis by immune insults: roles and interactions of cytokines, eicosanoids, glucocorticoids.

scientific article

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis.

scientific article published on 29 November 2016

An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone

scientific journal article

An investigation into pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and mutant male mice.

scientific article

Annexin A1 in the brain--undiscovered roles?

scientific article published on 11 February 2008

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization

scientific article

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia.

scientific article

Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis

scientific article published on 01 January 2000

Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice.

scientific article published on February 2003

Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals

scientific article

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal

scientific article published on 20 April 2016

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.

scientific article

Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration

scientific article published in 2018

Characterisation of a mural cell network in the murine pituitary gland

scientific article published on 31 August 2020

Characterization and Localization of Lipocortin 1-Binding Sites on Rat Anterior Pituitary Cells by Fluorescence-Activated Cell Analysis/Sorting and Electron Microscopy* ⬇️

scientific article published on December 1, 1997

Circadian clock mechanism driving mammalian photoperiodism

scientific article published on 27 August 2020

Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals

scientific article published on November 2016

Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1.

scientific article

Disentangling juxtacrine from paracrine signalling in dynamic tissue

scientific article published on 13 June 2019

Dissociation of nitric oxide synthase immunoreactivity and NADPH-diaphorase enzyme activity in rat pituitary.

scientific article published in September 1997

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

scientific article published on 17 February 2016

Effects of exogenous and endogenous prostaglandins on the fast phase of contraction of the guinea-pig vas deferens produced by electrical field stimulation

scientific article published on 01 July 1994

Evidence for a role of the adenosine 5'-triphosphate-binding cassette transporter A1 in the externalization of annexin I from pituitary folliculo-stellate cells.

scientific article published on March 2003

Existence of long-lasting experience-dependent plasticity in endocrine cell networks.

scientific article

Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.

scientific article published on 19 July 2016

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

scientific article

Human kidney pericytes produce renin.

scientific article published on 24 September 2016

Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel

scientific article published in 2022

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications

scientific article

Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.

scientific article published on 13 May 2013

Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells.

scientific article published on September 1999

Localisation and semi-quantitative measurement of lipocortin 1 in rat anterior pituitary cells by fluorescence-activated cell analysis/sorting and electron microscopy.

scientific article published in September 1999

Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction.

scientific article published in January 2001

Non-classical actions of testosterone: an update.

scientific article published on 9 November 2007

Nongenomic actions of testosterone on a subset of lactotrophs in the male rat pituitary

scientific article published on 01 September 2000

Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells

scientific article published on 31 December 2014

P19 Sex dimorphism in anterior pituitary glucocorticoid feedback revealed by annexin 1 knockout in mice

scientific article published on 01 November 2002

Phenotypic dissection of the mouse Ren-1(d) knockout by complementation with human renin.

scientific article

Pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and follicle-stimulating hormone β knockout, follicle-stimulating hormone receptor knockout, luteinising hormone receptor knockout, hypogonada

scientific article published on November 2014

Rapid actions of 17beta-oestradiol on a subset of lactotrophs in the rat pituitary.

scientific article published in March 2002

Role of Annexin A1 in mouse myoblast cell differentiation.

scientific article published on September 2010

S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation

scientific article published on 02 July 2019

Spatially coordinated dynamic gene transcription in living pituitary tissue

scientific article

The SLC16 monocaboxylate transporter family

scientific article published in July 2008

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.

scientific article published in April 2008

The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia

scientific article published on 12 September 2013

Thyrotrophin-releasing hormone, vasoactive intestinal peptide, prolactin-releasing peptide and dopamine regulation of prolactin secretion by different lactotroph morphological subtypes in the rat.

scientific article

Ultrastructural changes in lactotrophs and folliculo-stellate cells in the ovine pituitary during the annual reproductive cycle.

scientific article published in April 2015

Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target cell-induced acylation

scientific article

Vascular endothelial growth factor secretion from pituitary folliculostellate cells: role of KATP channels.

scientific article published on February 2014

Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations

scientific article

List of works by Helen Christian

Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

Activation of the HPA axis by immune insults: roles and interactions of cytokines, eicosanoids, glucocorticoids.

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis.

An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone

An investigation into pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and mutant male mice.

Annexin A1 in the brain--undiscovered roles?

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia.

Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis

Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice.

Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.

Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration

Characterisation of a mural cell network in the murine pituitary gland

Characterization and Localization of Lipocortin 1-Binding Sites on Rat Anterior Pituitary Cells by Fluorescence-Activated Cell Analysis/Sorting and Electron Microscopy* ⬇️

Circadian clock mechanism driving mammalian photoperiodism

Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals

Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1.

Disentangling juxtacrine from paracrine signalling in dynamic tissue

Dissociation of nitric oxide synthase immunoreactivity and NADPH-diaphorase enzyme activity in rat pituitary.

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

Effects of exogenous and endogenous prostaglandins on the fast phase of contraction of the guinea-pig vas deferens produced by electrical field stimulation

Evidence for a role of the adenosine 5'-triphosphate-binding cassette transporter A1 in the externalization of annexin I from pituitary folliculo-stellate cells.

Existence of long-lasting experience-dependent plasticity in endocrine cell networks.

Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart

Human kidney pericytes produce renin.

Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications

Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.

Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells.

Localisation and semi-quantitative measurement of lipocortin 1 in rat anterior pituitary cells by fluorescence-activated cell analysis/sorting and electron microscopy.

Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction.

Non-classical actions of testosterone: an update.

Nongenomic actions of testosterone on a subset of lactotrophs in the male rat pituitary

Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells

P19 Sex dimorphism in anterior pituitary glucocorticoid feedback revealed by annexin 1 knockout in mice

Phenotypic dissection of the mouse Ren-1(d) knockout by complementation with human renin.

Pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and follicle-stimulating hormone β knockout, follicle-stimulating hormone receptor knockout, luteinising hormone receptor knockout, hypogonada

Rapid actions of 17beta-oestradiol on a subset of lactotrophs in the rat pituitary.

Role of Annexin A1 in mouse myoblast cell differentiation.

S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation

Spatially coordinated dynamic gene transcription in living pituitary tissue

The SLC16 monocaboxylate transporter family

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.

The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia

Thyrotrophin-releasing hormone, vasoactive intestinal peptide, prolactin-releasing peptide and dopamine regulation of prolactin secretion by different lactotroph morphological subtypes in the rat.

Ultrastructural changes in lactotrophs and folliculo-stellate cells in the ovine pituitary during the annual reproductive cycle.

Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target cell-induced acylation

Vascular endothelial growth factor secretion from pituitary folliculostellate cells: role of KATP channels.

Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations