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List of works by Brad D. Jones

A high-throughput genetic system for assessing the inhibition of proteins: identification of antibiotic resistance and virulence targets and their cognate inhibitors in Salmonella.

scientific article

An in vitro model system used to study adherence and invasion of Francisella tularensis live vaccine strain in nonphagocytic cells.

scientific article

Bacterial lipoproteins and other factors released by Francisella tularensis modulate human neutrophil lifespan: Effects of a TLR1 SNP on apoptosis inhibition

scientific article published on 23 October 2017

Biofilm formation by Salmonella enterica serovar Typhimurium and Escherichia coli on epithelial cells following mixed inoculations.

scientific article published on August 2005

Characterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficiencies

scientific article published on 5 May 2015

Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence

scientific article published on 2 August 2010

Differential binding to and biofilm formation on, HEp-2 cells by Salmonella enterica serovar Typhimurium is dependent upon allelic variation in the fimH gene of the fim gene cluster.

scientific article published on September 2002

Early epithelial invasion by Salmonella enterica serovar Typhimurium DT104 in the swine ileum.

scientific article published in November 2002

Exopolysaccharide sugars contribute to biofilm formation by Salmonella enterica serovar typhimurium on HEp-2 cells and chicken intestinal epithelium.

scientific article published on May 2005

Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.

scientific article

Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.

scientific article published on 31 October 2012

Hha is a negative modulator of transcription of hilA, the Salmonella enterica serovar Typhimurium invasion gene transcriptional activator ⬇️

scientific article

HilE interacts with HilD and negatively regulates hilA transcription and expression of the Salmonella enterica serovar Typhimurium invasive phenotype. ⬇️

scientific article

Host responses to pathogenic Salmonella infection.

scientific article published on March 1997

Identification of Listeria monocytogenes in vivo-induced genes by fluorescence-activated cell sorting

scientific article

Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants ⬇️

scientific article published on March 1, 1992

Identification of differentially regulated francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system.

scientific article published on 14 March 2008

Identification of diminished tissue culture invasiveness among multiple antibiotic resistant Salmonella typhimurium DT104.

scientific article

Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages.

scientific article published on 06 April 2009

Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

scientific article

Immunization with outer membrane vesicles displaying conserved surface polysaccharide antigen elicits broadly antimicrobial antibodies.

scientific article published on 19 March 2018

Inclusion of Epitopes That Expand High-Avidity CD4+ T Cells Transforms Subprotective Vaccines to Efficacious Immunogens against Virulent Francisella tularensis

scientific article published on 19 August 2016

Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium.

scientific article published on 26 May 2015

Lon protease activity causes down-regulation of Salmonella pathogenicity island 1 invasion gene expression after infection of epithelial cells.

scientific article published on April 2004

Metabolic Reprogramming of Host Cells by Virulent Francisella tularensis for Optimal Replication and Modulation of Inflammation.

scientific article published on 30 March 2016

Metabolic engineering of Salmonella vaccine bacteria to boost human Vγ2Vδ2 T cell immunity.

scientific article

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis.

scientific article

Mutation of the htrB gene in a virulent Salmonella typhimurium strain by intergeneric transduction: strain construction and phenotypic characterization

scientific article published on September 1997

Salmonella enterica serovar Typhimurium requires nonsterol precursors of the cholesterol biosynthetic pathway for intracellular proliferation

scientific article published on February 2004

Salmonella enterica serovar Typhimurium requires the Lpf, Pef, and Tafi fimbriae for biofilm formation on HEp-2 tissue culture cells and chicken intestinal epithelium.

scientific article published on June 2006

Salmonella enterica serovars gallinarum and pullorum expressing Salmonella enterica serovar typhimurium type 1 fimbriae exhibit increased invasiveness for mammalian cells. ⬇️

scientific article published on August 2000

Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system

scientific journal article

Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane.

scientific article published in May 2001

Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches.

scientific article

Salmonellosis: host immune responses and bacterial virulence determinants.

scientific article published on January 1996

Secretion of a putative cytotoxin in multiple antibiotic resistant Salmonella enterica serotype Typhimurium phagetype DT104.

scientific article published in October 2001

The Ability to Acquire Iron Is Inversely Related to Virulence and the Protective Efficacy of Francisella tularensis Live Vaccine Strain.

scientific article published on 4 April 2018

The Francisella tularensis migR, trmE, and cphA genes contribute to F. tularensis pathogenicity island gene regulation and intracellular growth by modulation of the stress alarmone ppGpp

scientific article published on 28 May 2013

Transcription of the Salmonella invasion gene activator, hilA, requires HilD activation in the absence of negative regulators.

scientific article published on January 2003

Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes

scientific article

Two-component regulators control hilA expression by controlling fimZ and hilE expression within Salmonella enterica serovar Typhimurium.

scientific article published on 29 December 2014

Uncovering the components of the Francisella tularensis virulence stealth strategy

scientific article published on 07 March 2014

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